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Article: Genetic characterization and evolutionary analysis of 4 Newcastle disease virus isolate full genomes from waterbirds in South China during 2003-2007

TitleGenetic characterization and evolutionary analysis of 4 Newcastle disease virus isolate full genomes from waterbirds in South China during 2003-2007
Authors
Cai, SLi, JWong, MTJiao, PFan, HLiu, DLiao, MJiang, JShi, MLam, TTYRen, TLeung, FCC
KeywordsEvolutionary analysis
Newcastle disease virus
Phylogenetic tree
Phylogenomic tree
Phylogeographic
Selective pressure
Waterfowls
Issue Date2011
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/vetmic
Citation
Veterinary Microbiology, 2011, v. 152 n. 1-2, p. 46-54 How to Cite?
DOI: http://dx.doi.org/10.1016/j.vetmic.2011.04.014
AbstractComplete genomes of four Newcastle disease virus (NDV) strains, isolated from ducks and wild birds in Guangdong province of China from 2003 to 2007, were sequenced and analyzed in this study. Pathogenicity tests in chicken embryos and chickens illustrate that D3 and R8 are lentogenic, and W4 and P4 are mesogenic strains. Phylogenetic analysis using all six genes provides a high resolution profile for genotype designation as genotype I for D3 and R8 strains and genotype VI for W4 and P4 strains. In addition, molecular dating based on different genes suggests that D3 and R8 diverged from their common ancestor at around 1998; W4 and P4 diverged from their common ancestor at around 1999. Subsequent selective pressure analysis displayed specific traits of genes evolution in all 4 strains since their divergence from the recent common ancestor. Furthermore, the geographic origins of 4 strains were deduced to be from Europe via two independent introduction events by phylogeographical analysis. This provides insights to the potential influence of waterfowl migration on NDV epidemiology. © 2011 Elsevier B.V.
Persistent Identifierhttp://hdl.handle.net/10722/140928
ISSN
0378-1135
2023 Impact Factor: 2.4
2023 SCImago Journal Rankings: 0.653
ISI Accession Number ID
WOS:000294095000005
Funding AgencyGrant Number
Changjiang Scholars and Innovative Research Team in UniversityIRT0723
The National High Technology Research and Development Program of China2006AA10A205
Science and Technology Planning Project of Guangdong Province, China2005A20401003
Public Industry (Agriculture) Specific Research Program200803020-08
The University of Hong Kong
Funding Information:

This project was supported by Program for Changjiang Scholars and Innovative Research Team in University (IRT0723), The National High Technology Research and Development Program of China (2006AA10A205), Science and Technology Planning Project of Guangdong Province, China (2005A20401003), and Public Industry (Agriculture) Specific Research Program (200803020-08). This project is also partly supported by the Strategic Research Theme of Infection and Immunology, The University of Hong Kong.

References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorCai, Sen_HK
dc.contributor.authorLi, Jen_HK
dc.contributor.authorWong, MTen_HK
dc.contributor.authorJiao, Pen_HK
dc.contributor.authorFan, Hen_HK
dc.contributor.authorLiu, Den_HK
dc.contributor.authorLiao, Men_HK
dc.contributor.authorJiang, Jen_HK
dc.contributor.authorShi, Men_HK
dc.contributor.authorLam, TTYen_HK
dc.contributor.authorRen, Ten_HK
dc.contributor.authorLeung, FCCen_HK
dc.date.accessioned2011-09-23T06:21:31Z-
dc.date.available2011-09-23T06:21:31Z-
dc.date.issued2011en_HK
dc.identifier.citationVeterinary Microbiology, 2011, v. 152 n. 1-2, p. 46-54en_HK
dc.identifier.issn0378-1135en_HK
dc.identifier.urihttp://hdl.handle.net/10722/140928-
dc.description.abstractComplete genomes of four Newcastle disease virus (NDV) strains, isolated from ducks and wild birds in Guangdong province of China from 2003 to 2007, were sequenced and analyzed in this study. Pathogenicity tests in chicken embryos and chickens illustrate that D3 and R8 are lentogenic, and W4 and P4 are mesogenic strains. Phylogenetic analysis using all six genes provides a high resolution profile for genotype designation as genotype I for D3 and R8 strains and genotype VI for W4 and P4 strains. In addition, molecular dating based on different genes suggests that D3 and R8 diverged from their common ancestor at around 1998; W4 and P4 diverged from their common ancestor at around 1999. Subsequent selective pressure analysis displayed specific traits of genes evolution in all 4 strains since their divergence from the recent common ancestor. Furthermore, the geographic origins of 4 strains were deduced to be from Europe via two independent introduction events by phylogeographical analysis. This provides insights to the potential influence of waterfowl migration on NDV epidemiology. © 2011 Elsevier B.V.en_HK
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/vetmicen_HK
dc.relation.ispartofVeterinary Microbiologyen_HK
dc.subjectEvolutionary analysisen_HK
dc.subjectNewcastle disease virusen_HK
dc.subjectPhylogenetic treeen_HK
dc.subjectPhylogenomic treeen_HK
dc.subjectPhylogeographicen_HK
dc.subjectSelective pressureen_HK
dc.subjectWaterfowlsen_HK
dc.subject.meshEvolution, Molecular-
dc.subject.meshGenome, Viral-
dc.subject.meshNewcastle Disease - epidemiology - virology-
dc.subject.meshNewcastle disease virus - genetics - isolation and purification-
dc.subject.meshPhylogeny-
dc.titleGenetic characterization and evolutionary analysis of 4 Newcastle disease virus isolate full genomes from waterbirds in South China during 2003-2007en_HK
dc.typeArticleen_HK
dc.identifier.emailLam, TTY: ttylam@hku.hken_HK
dc.identifier.emailLeung, FCC: fcleung@hkucc.hku.hken_HK
dc.identifier.authorityLam, TTY=rp01733en_HK
dc.identifier.authorityLeung, FCC=rp00731en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.vetmic.2011.04.014en_HK
dc.identifier.pmid21565454-
dc.identifier.scopuseid_2-s2.0-79960403262en_HK
dc.identifier.hkuros195158en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79960403262&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume152en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage46en_HK
dc.identifier.epage54en_HK
dc.identifier.isiWOS:000294095000005-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridCai, S=54082780200en_HK
dc.identifier.scopusauthoridLi, J=36066643600en_HK
dc.identifier.scopusauthoridWong, MT=54379338400en_HK
dc.identifier.scopusauthoridJiao, P=8558834200en_HK
dc.identifier.scopusauthoridFan, H=8669644400en_HK
dc.identifier.scopusauthoridLiu, D=54179538800en_HK
dc.identifier.scopusauthoridLiao, M=7202371672en_HK
dc.identifier.scopusauthoridJiang, J=35310401200en_HK
dc.identifier.scopusauthoridShi, M=25951822000en_HK
dc.identifier.scopusauthoridLam, TTY=36775821700en_HK
dc.identifier.scopusauthoridRen, T=36139729300en_HK
dc.identifier.scopusauthoridLeung, FCC=7103078633en_HK
dc.identifier.citeulike9231305-
dc.identifier.issnl0378-1135-

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