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Article: B cell-targeted therapy for rheumatoid arthritis
| Title | B cell-targeted therapy for rheumatoid arthritis 類風濕關節炎的B細胞靶向治療進展 |
|---|---|
| Authors | |
| Issue Date | 2011 |
| Publisher | 上海市免疫學院研究所. The Journal's web site is located at http://shmy.chinajournal.net.cn/ |
| Citation | 現代免疫學, 2011, v. 31 n. 3, p. 180-182 How to Cite? Current Immunology, 2011, v. 31 n. 3, p. 180-182 How to Cite? |
| Abstract | 類風濕關節炎(rheumatoid arthritis,RA)是以慢性滑膜炎癥、進行性骨質破壞和關節功能喪失為特征的自身免疫性疾病。目前針對RA的治療以免疫抑制劑為主。近年來生物制劑如TNF-α、IL-6單抗等應用于臨床,但均不能完全控制炎癥進展,且存在病人耐受性差、易發生結核等繼發感染的副作用。因此,深入探討RA的免疫病理機制及研發新型免疫治疗方法对于RA 的临床治疗有重要意义。 |
| Persistent Identifier | http://hdl.handle.net/10722/137629 |
| ISSN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lu, L | en_US |
| dc.date.accessioned | 2011-08-26T14:29:43Z | - |
| dc.date.available | 2011-08-26T14:29:43Z | - |
| dc.date.issued | 2011 | en_US |
| dc.identifier.citation | 現代免疫學, 2011, v. 31 n. 3, p. 180-182 | zh_HK |
| dc.identifier.citation | Current Immunology, 2011, v. 31 n. 3, p. 180-182 | - |
| dc.identifier.issn | 1001-2478 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/137629 | - |
| dc.description.abstract | 類風濕關節炎(rheumatoid arthritis,RA)是以慢性滑膜炎癥、進行性骨質破壞和關節功能喪失為特征的自身免疫性疾病。目前針對RA的治療以免疫抑制劑為主。近年來生物制劑如TNF-α、IL-6單抗等應用于臨床,但均不能完全控制炎癥進展,且存在病人耐受性差、易發生結核等繼發感染的副作用。因此,深入探討RA的免疫病理機制及研發新型免疫治疗方法对于RA 的临床治疗有重要意义。 | zh_HK |
| dc.language | chi | en_US |
| dc.publisher | 上海市免疫學院研究所. The Journal's web site is located at http://shmy.chinajournal.net.cn/ | zh_HK |
| dc.relation.ispartof | 現代免疫學 | zh_HK |
| dc.relation.ispartof | Current Immunology | - |
| dc.title | B cell-targeted therapy for rheumatoid arthritis | en_US |
| dc.title | 類風濕關節炎的B細胞靶向治療進展 | zh_HK |
| dc.type | Article | en_US |
| dc.identifier.email | Lu, L: liweilu@hkucc.hku.hk | en_US |
| dc.identifier.authority | Lu, L=rp00477 | en_US |
| dc.identifier.hkuros | 191300 | en_US |
| dc.identifier.volume | 31 | en_US |
| dc.identifier.issue | 3 | - |
| dc.identifier.spage | 180 | en_US |
| dc.identifier.epage | 182 | en_US |
| dc.publisher.place | China | - |
| dc.identifier.issnl | 1001-2478 | - |