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Conference Paper: Replication and innate host response of influenza A virus in lung microvascular endothelial cells: new insights into systemic infection and pathogenesis

TitleReplication and innate host response of influenza A virus in lung microvascular endothelial cells: new insights into systemic infection and pathogenesis
Authors
KeywordsAvian H5N1 virus
Cytokine
Human seasonal H1N1 virus
Microvascular endothelial cells
Pandemic H1N1pdm virus
Issue Date2011
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1
Citation
The 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 suppl. 1, p. 287-288 How to Cite?
AbstractINTRODUCTION: Though influenza A virus replication kinetics and host responses have been previously studied in umbilical vein endothelial cell or transformed endothelial cell lines, the tropism of influenza A virus including H5N1 and pandemic H1N1pdm for primary human lung microvascular endothelial cell has not been well defined.1 In this study we employed primary human lung microvascular endothelial cells, which are more physiologically relevant for understanding pathogenesis of influenza in the lung as to obtain a better understanding of the links of endothelial cell infection to systematic virus dissemination and multiple organ involvement in severe human influenza …
Persistent Identifierhttp://hdl.handle.net/10722/135688
ISSN
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.485

 

DC FieldValueLanguage
dc.contributor.authorLi, ACLen_US
dc.contributor.authorChan, RWYen_US
dc.contributor.authorHui, CFFen_US
dc.contributor.authorKang, SSRen_US
dc.contributor.authorYu, WCLen_US
dc.contributor.authorNicholls, JMen_US
dc.contributor.authorChan, MCWen_US
dc.date.accessioned2011-07-27T01:39:26Z-
dc.date.available2011-07-27T01:39:26Z-
dc.date.issued2011en_US
dc.identifier.citationThe 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 suppl. 1, p. 287-288en_US
dc.identifier.issn1750-2640-
dc.identifier.urihttp://hdl.handle.net/10722/135688-
dc.description.abstractINTRODUCTION: Though influenza A virus replication kinetics and host responses have been previously studied in umbilical vein endothelial cell or transformed endothelial cell lines, the tropism of influenza A virus including H5N1 and pandemic H1N1pdm for primary human lung microvascular endothelial cell has not been well defined.1 In this study we employed primary human lung microvascular endothelial cells, which are more physiologically relevant for understanding pathogenesis of influenza in the lung as to obtain a better understanding of the links of endothelial cell infection to systematic virus dissemination and multiple organ involvement in severe human influenza …-
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1-
dc.relation.ispartofInfluenza and Other Respiratory Virusesen_US
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subjectAvian H5N1 virus-
dc.subjectCytokine-
dc.subjectHuman seasonal H1N1 virus-
dc.subjectMicrovascular endothelial cells-
dc.subjectPandemic H1N1pdm virus-
dc.titleReplication and innate host response of influenza A virus in lung microvascular endothelial cells: new insights into systemic infection and pathogenesisen_US
dc.typeConference_Paperen_US
dc.identifier.emailLi, ACL: alancl@hku.hken_US
dc.identifier.emailChan, RWY: reneechan@graduate.hku.hk, reneewy@hku.hken_US
dc.identifier.emailHui, CFF: celineh@hku.hken_US
dc.identifier.emailKang, SSR: sarakang@hku.hken_US
dc.identifier.emailYu, WCL: wendyucl@hkucc.hku.hken_US
dc.identifier.emailNicholls, JM: jmnichol@hkucc.hku.hken_US
dc.identifier.emailChan, MCW: mchan@hku.hken_US
dc.identifier.authorityChan, RWY=rp01596en_US
dc.identifier.authorityNicholls, JM=rp00364en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1750-2659.2011.00209.x-
dc.identifier.hkuros187330en_US
dc.identifier.hkuros170678-
dc.identifier.volume5en_US
dc.identifier.issuesuppl. 1en_US
dc.identifier.spage287en_US
dc.identifier.epage288en_US
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl1750-2640-

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