File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Seroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kong

TitleSeroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kong
Authors
KeywordsH1N1
Healthcare workers
Influenza
Pandemic
Seroprevalence
Issue Date2011
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhin
Citation
Journal Of Hospital Infection, 2011, v. 78 n. 4, p. 308-311 How to Cite?
AbstractDuring the first wave of an influenza pandemic prior to the availability of an effective vaccine, healthcare workers (HCWs) may be at particular risk of infection with the novel influenza strain. We conducted a cross-sectional study of the prevalence of antibody to pandemic influenza A (H1N1) 2009 (pH1N1) among HCWs in Hong Kong in February-March 2010 following the first pandemic wave. Sera collected from HCWs were tested for antibody to pH1N1 influenza virus by viral neutralisation (VN). We assessed factors associated with higher antibody titres, and we compared antibody titres in HCWs with those in a separate community study. In total we enrolled 703 HCWs. Among 599 HCWs who did not report receipt of pH1N1 vaccine, 12% had antibody titre ≥1:40 by VN. There were no significant differences in the age-specific proportions of unvaccinated HCWs with antibody titre ≥1:40 compared with the general community following the first wave of pH1N1. Under good adherence to infection control guidelines, potential occupational exposures in the hospital setting did not appear to be associated with any substantial excess risk of pH1N1 infection in HCWs. Most HCWs had low antibody titres following the first pandemic wave. © 2011 The Healthcare Infection Society.
Persistent Identifierhttp://hdl.handle.net/10722/135667
ISSN
2023 Impact Factor: 3.9
2023 SCImago Journal Rankings: 1.095
ISI Accession Number ID
Funding AgencyGrant Number
MedImmune Inc.
Roche
Hong Kong University Grants CommitteeAoE/M-12/06
Food and Health Bureau, Government of the Hong Kong SARPHE-20
Funding Information:

B.J.C. has received research funding from MedImmune Inc., a manufacturer of influenza vaccines. D.K.M.I. has received research funding from Roche. The authors report no other potential conflicts of interest.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorZhou, Yen_HK
dc.contributor.authorNg, DMWen_HK
dc.contributor.authorSeto, WHen_HK
dc.contributor.authorIp, DKMen_HK
dc.contributor.authorKwok, HKHen_HK
dc.contributor.authorMa, ESKen_HK
dc.contributor.authorNg, Sen_HK
dc.contributor.authorLau, LLHen_HK
dc.contributor.authorWu, JTen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorCowling, BJen_HK
dc.date.accessioned2011-07-27T01:39:00Z-
dc.date.available2011-07-27T01:39:00Z-
dc.date.issued2011en_HK
dc.identifier.citationJournal Of Hospital Infection, 2011, v. 78 n. 4, p. 308-311en_HK
dc.identifier.issn0195-6701en_HK
dc.identifier.urihttp://hdl.handle.net/10722/135667-
dc.description.abstractDuring the first wave of an influenza pandemic prior to the availability of an effective vaccine, healthcare workers (HCWs) may be at particular risk of infection with the novel influenza strain. We conducted a cross-sectional study of the prevalence of antibody to pandemic influenza A (H1N1) 2009 (pH1N1) among HCWs in Hong Kong in February-March 2010 following the first pandemic wave. Sera collected from HCWs were tested for antibody to pH1N1 influenza virus by viral neutralisation (VN). We assessed factors associated with higher antibody titres, and we compared antibody titres in HCWs with those in a separate community study. In total we enrolled 703 HCWs. Among 599 HCWs who did not report receipt of pH1N1 vaccine, 12% had antibody titre ≥1:40 by VN. There were no significant differences in the age-specific proportions of unvaccinated HCWs with antibody titre ≥1:40 compared with the general community following the first wave of pH1N1. Under good adherence to infection control guidelines, potential occupational exposures in the hospital setting did not appear to be associated with any substantial excess risk of pH1N1 infection in HCWs. Most HCWs had low antibody titres following the first pandemic wave. © 2011 The Healthcare Infection Society.en_HK
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhinen_HK
dc.relation.ispartofJournal of Hospital Infectionen_HK
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication inJournal of Hospital Infection. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Hospital Infection, 2011, v. 78 n. 4, p. 308-311. DOI: 10.1016/j.jhin.2011.02.017-
dc.subjectH1N1en_HK
dc.subjectHealthcare workersen_HK
dc.subjectInfluenzaen_HK
dc.subjectPandemicen_HK
dc.subjectSeroprevalenceen_HK
dc.titleSeroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0195-6701&volume=78&issue=4&spage=308&epage=311&date=2011&atitle=Seroprevalence+of+antibody+to+pandemic+influenza+A+(H1N1)+2009+among+healthcare+workers+after+the+first+wave+in+Hong+Kong-
dc.identifier.emailIp, DKM: dkmip@hku.hken_HK
dc.identifier.emailWu, JT: joewu@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailCowling, BJ: bcowling@hku.hken_HK
dc.identifier.authorityIp, DKM=rp00256en_HK
dc.identifier.authorityWu, JT=rp00517en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityCowling, BJ=rp01326en_HK
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.jhin.2011.02.017en_HK
dc.identifier.pmid21501896-
dc.identifier.scopuseid_2-s2.0-79960184071en_HK
dc.identifier.hkuros188109en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79960184071&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume78en_HK
dc.identifier.issue4en_HK
dc.identifier.spage308en_HK
dc.identifier.epage311en_HK
dc.identifier.isiWOS:000292682400013-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.relation.projectA detailed longitudinal study of infection attack rates among healthy adults in Hong Kong during the epidemic of the human swine influenza A/H1N1 virus in 2009-
dc.identifier.scopusauthoridZhou, Y=35319149100en_HK
dc.identifier.scopusauthoridNg, DMW=36497437400en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.scopusauthoridIp, DKM=35117701600en_HK
dc.identifier.scopusauthoridKwok, HKH=26644099900en_HK
dc.identifier.scopusauthoridMa, ESK=24725277400en_HK
dc.identifier.scopusauthoridNg, S=34977173400en_HK
dc.identifier.scopusauthoridLau, LLH=36010688600en_HK
dc.identifier.scopusauthoridWu, JT=7409256423en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridCowling, BJ=8644765500en_HK
dc.identifier.issnl0195-6701-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats