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- Publisher Website: 10.1517/14656566.2010.511613
- Scopus: eid_2-s2.0-78149421069
- PMID: 20707597
- WOS: WOS:000283871600008
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Article: Alpha-2 agonists in acute pain management
Title | Alpha-2 agonists in acute pain management |
---|---|
Authors | |
Keywords | Acute pain Alpha-2 agonist Analgesia Clonidine Dexmedetomidine Fadolmidine |
Issue Date | 2010 |
Publisher | Informa Healthcare. The Journal's web site is located at http://www.expertopin.com/loi/eop |
Citation | Expert Opinion On Pharmacotherapy, 2010, v. 11 n. 17, p. 2849-2868 How to Cite? |
Abstract | Importance of the field: This review explores the significance of alpha-2 agonists used clinically in acute pain management. Areas covered in this review: Although alpha-2 agonists have been reported to have an analgesic effect, they are not commonly used clinically for acute pain management. Clinical studies on use of alpha-2 agonists for acute pain management are reviewed and discussed. A literature search was done using Medline with the keywords 'alpha-2 agonist', 'clonidine', 'dexmedetomidine', 'fadolmidine', 'pharmacokinetics', 'pharmacodynamics', 'postoperative analgesia', 'epidural', 'intrathecal', 'peripheral nerve block' and various combinations with these keywords. The years 1977 2009 have been included, with particular focus on clinical studies from between 1990 and 2009. What the reader will gain: This article helps to clarify the clinical use of alpha-2 agonists in acute pain management according to current, up-to-date evidence. Clinically, available alpha-2 agonists, including clonidine and dexmedetomidine, are discussed in detail. Take home message: Alpha-2 agonists, especially clonidine, seem to be promising with regard to acute postoperative pain management. However, more clinical evidence on dexmedetomidine is necessary to confirm its definite role in acute postoperative pain control. © 2010 Informa UK, Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/133494 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.687 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, AKM | en_HK |
dc.contributor.author | Cheung, CW | en_HK |
dc.contributor.author | Chong, YK | en_HK |
dc.date.accessioned | 2011-05-16T07:30:43Z | - |
dc.date.available | 2011-05-16T07:30:43Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Expert Opinion On Pharmacotherapy, 2010, v. 11 n. 17, p. 2849-2868 | en_HK |
dc.identifier.issn | 1465-6566 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/133494 | - |
dc.description.abstract | Importance of the field: This review explores the significance of alpha-2 agonists used clinically in acute pain management. Areas covered in this review: Although alpha-2 agonists have been reported to have an analgesic effect, they are not commonly used clinically for acute pain management. Clinical studies on use of alpha-2 agonists for acute pain management are reviewed and discussed. A literature search was done using Medline with the keywords 'alpha-2 agonist', 'clonidine', 'dexmedetomidine', 'fadolmidine', 'pharmacokinetics', 'pharmacodynamics', 'postoperative analgesia', 'epidural', 'intrathecal', 'peripheral nerve block' and various combinations with these keywords. The years 1977 2009 have been included, with particular focus on clinical studies from between 1990 and 2009. What the reader will gain: This article helps to clarify the clinical use of alpha-2 agonists in acute pain management according to current, up-to-date evidence. Clinically, available alpha-2 agonists, including clonidine and dexmedetomidine, are discussed in detail. Take home message: Alpha-2 agonists, especially clonidine, seem to be promising with regard to acute postoperative pain management. However, more clinical evidence on dexmedetomidine is necessary to confirm its definite role in acute postoperative pain control. © 2010 Informa UK, Ltd. | en_HK |
dc.language | eng | - |
dc.publisher | Informa Healthcare. The Journal's web site is located at http://www.expertopin.com/loi/eop | en_HK |
dc.relation.ispartof | Expert Opinion on Pharmacotherapy | en_HK |
dc.rights | Expert Opinion on Pharmacotherapy. Copyright © Informa Healthcare. | - |
dc.subject | Acute pain | en_HK |
dc.subject | Alpha-2 agonist | en_HK |
dc.subject | Analgesia | en_HK |
dc.subject | Clonidine | en_HK |
dc.subject | Dexmedetomidine | en_HK |
dc.subject | Fadolmidine | en_HK |
dc.subject.mesh | Acute Disease | - |
dc.subject.mesh | Adrenergic alpha-2 Receptor Agonists - pharmacology - therapeutic use | - |
dc.subject.mesh | Analgesics - pharmacology - therapeutic use | - |
dc.subject.mesh | Humans | - |
dc.subject.mesh | Pain - drug therapy | - |
dc.title | Alpha-2 agonists in acute pain management | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1465-6566&volume=11&issue=17&spage=2849&epage=2868&date=2010&atitle=Alpha-2+agonists+in+acute+pain+management | - |
dc.identifier.email | Cheung, CW:cheucw@hku.hk | en_HK |
dc.identifier.authority | Cheung, CW=rp00244 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1517/14656566.2010.511613 | en_HK |
dc.identifier.pmid | 20707597 | - |
dc.identifier.scopus | eid_2-s2.0-78149421069 | en_HK |
dc.identifier.hkuros | 183245 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-78149421069&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 11 | en_HK |
dc.identifier.issue | 17 | en_HK |
dc.identifier.spage | 2849 | en_HK |
dc.identifier.epage | 2868 | en_HK |
dc.identifier.isi | WOS:000283871600008 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.citeulike | 8239534 | - |
dc.identifier.issnl | 1465-6566 | - |