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Article: Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique

TitleCorrecting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique
Authors
KeywordsAutoimmune anomalies
Modified vaccination technique
Prophylactic
Therapeutic
Tolerance to self
Issue Date2009
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/autrev
Citation
Autoimmunity Reviews, 2009, v. 8 n. 7, p. 552-557 How to Cite?
AbstractOur research group has developed a new vaccination technique in experimental animals that has the potential of correcting autoimmune anomalies in humans such as autoimmune disorders, cancer, and chronic infections, both prophylactically and therapeutically. The vaccination method is called Modified Vaccination Technique (MVT). The MVT necessitates the introduction of a purified target antigen (ag) and a specific antibody (ab) against the target ag in the form of immune complex (IC) to evoke the desired immune response outcome by ab information transfer in the injected recipient. The injected IC produces the same class of ab in the host, with the same specificity against the target ag, as resides in the inoculum. The MVT promises to provide a means of upregulating beneficial immune events and downregulating undesirable immune responses in individuals, thereby re-establishing normalcy/tolerance to self. © 2009 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/132548
ISSN
2023 Impact Factor: 9.2
2023 SCImago Journal Rankings: 2.677
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBarabas, AZen_HK
dc.contributor.authorCole, CDen_HK
dc.contributor.authorBarabas, ADen_HK
dc.contributor.authorGraeff, RMen_HK
dc.contributor.authorLafreniere, Ren_HK
dc.contributor.authorWeir, DMen_HK
dc.date.accessioned2011-03-28T09:26:11Z-
dc.date.available2011-03-28T09:26:11Z-
dc.date.issued2009en_HK
dc.identifier.citationAutoimmunity Reviews, 2009, v. 8 n. 7, p. 552-557en_HK
dc.identifier.issn1568-9972en_HK
dc.identifier.urihttp://hdl.handle.net/10722/132548-
dc.description.abstractOur research group has developed a new vaccination technique in experimental animals that has the potential of correcting autoimmune anomalies in humans such as autoimmune disorders, cancer, and chronic infections, both prophylactically and therapeutically. The vaccination method is called Modified Vaccination Technique (MVT). The MVT necessitates the introduction of a purified target antigen (ag) and a specific antibody (ab) against the target ag in the form of immune complex (IC) to evoke the desired immune response outcome by ab information transfer in the injected recipient. The injected IC produces the same class of ab in the host, with the same specificity against the target ag, as resides in the inoculum. The MVT promises to provide a means of upregulating beneficial immune events and downregulating undesirable immune responses in individuals, thereby re-establishing normalcy/tolerance to self. © 2009 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/autreven_HK
dc.relation.ispartofAutoimmunity Reviewsen_HK
dc.subjectAutoimmune anomaliesen_HK
dc.subjectModified vaccination techniqueen_HK
dc.subjectProphylacticen_HK
dc.subjectTherapeuticen_HK
dc.subjectTolerance to selfen_HK
dc.titleCorrecting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination techniqueen_HK
dc.typeArticleen_HK
dc.identifier.emailGraeff, RM: graeffr@hku.hken_HK
dc.identifier.authorityGraeff, RM=rp01464en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.autrev.2009.01.014en_HK
dc.identifier.pmid19393215-
dc.identifier.scopuseid_2-s2.0-67349172922en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67349172922&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume8en_HK
dc.identifier.issue7en_HK
dc.identifier.spage552en_HK
dc.identifier.epage557en_HK
dc.identifier.isiWOS:000267567300005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridBarabas, AZ=7005562572en_HK
dc.identifier.scopusauthoridCole, CD=8942475100en_HK
dc.identifier.scopusauthoridBarabas, AD=7005562583en_HK
dc.identifier.scopusauthoridGraeff, RM=7003614053en_HK
dc.identifier.scopusauthoridLafreniere, R=7006983863en_HK
dc.identifier.scopusauthoridWeir, DM=7202838101en_HK
dc.identifier.citeulike5468944-
dc.identifier.issnl1568-9972-

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