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- Publisher Website: 10.4161/psb.5.8.12294
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- PMID: 20657176
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Article: Protein interactors of acyl-CoA-binding protein ACBP2 mediate cadmium tolerance in arabidopsis
Title | Protein interactors of acyl-CoA-binding protein ACBP2 mediate cadmium tolerance in arabidopsis |
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Authors | |
Keywords | Acyl-CoA-binding protein Cadmium Hydrogen peroxide Lysophospholipase Oxidative stress |
Issue Date | 2010 |
Publisher | Landes Bioscience. The Journal's web site is located at http://www.landesbioscience.com/journals/psb |
Citation | Plant Signaling And Behavior, 2010, v. 5 n. 8, p. 1025-1027 How to Cite? |
Abstract | In our recent paper in the Plant Journal, we reported that Arabidopsis thaliana lysophospholipase 2 (lysoPL2) binds acyl-CoA-binding protein 2 (ACBP2) to mediate cadmium [Cd(II)] tolerance in transgenic Arabidopsis. ACBP2 contains ankyrin repeats that have been previously shown to mediate protein-protein interactions with an ethylene-responsive element binding protein (AtEBP) and a farnesylated protein 6 (AtFP6). Transgenic Arabidopsis ACBP2- overexpressors, lysoPL2-overexpressors and AtFP6-overexpressors all display enhanced Cd(II) tolerance, in comparison to wild type, suggesting that ACBP2 and its protein partners work together to mediate Cd(II) tolerance. Given that recombinant ACBP2 and AtFP6 can independently bind Cd(II) in vitro, they may be able to participate in Cd(II) translocation. The binding of recombinant ACBP2 to [14C]linoleoyl-CoA and [14C]linolenoyl-CoA implies its role in phospholipid repair. In conclusion, ACBP2 can mediate tolerance to Cd(II)- induced oxidative stress by interacting with two protein partners, AtFP6 and lysoPL2. Observations that ACBP2 also binds lysophosphatidylcholine (lysoPC) in vitro and that recombinant lysoPL2 degrades lysoPC, further confirm an interactive role for ACBP2 and lysoPL2 in overcoming Cd(II)-induced stress. © 2010 Landes Bioscience. |
Persistent Identifier | http://hdl.handle.net/10722/127448 |
ISSN | 2023 Impact Factor: 2.8 2023 SCImago Journal Rankings: 0.725 |
PubMed Central ID | |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gao, W | en_HK |
dc.contributor.author | Li, HY | en_HK |
dc.contributor.author | Xiao, S | en_HK |
dc.contributor.author | Chye, ML | en_HK |
dc.date.accessioned | 2010-10-31T13:26:09Z | - |
dc.date.available | 2010-10-31T13:26:09Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Plant Signaling And Behavior, 2010, v. 5 n. 8, p. 1025-1027 | en_HK |
dc.identifier.issn | 1559-2316 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/127448 | - |
dc.description.abstract | In our recent paper in the Plant Journal, we reported that Arabidopsis thaliana lysophospholipase 2 (lysoPL2) binds acyl-CoA-binding protein 2 (ACBP2) to mediate cadmium [Cd(II)] tolerance in transgenic Arabidopsis. ACBP2 contains ankyrin repeats that have been previously shown to mediate protein-protein interactions with an ethylene-responsive element binding protein (AtEBP) and a farnesylated protein 6 (AtFP6). Transgenic Arabidopsis ACBP2- overexpressors, lysoPL2-overexpressors and AtFP6-overexpressors all display enhanced Cd(II) tolerance, in comparison to wild type, suggesting that ACBP2 and its protein partners work together to mediate Cd(II) tolerance. Given that recombinant ACBP2 and AtFP6 can independently bind Cd(II) in vitro, they may be able to participate in Cd(II) translocation. The binding of recombinant ACBP2 to [14C]linoleoyl-CoA and [14C]linolenoyl-CoA implies its role in phospholipid repair. In conclusion, ACBP2 can mediate tolerance to Cd(II)- induced oxidative stress by interacting with two protein partners, AtFP6 and lysoPL2. Observations that ACBP2 also binds lysophosphatidylcholine (lysoPC) in vitro and that recombinant lysoPL2 degrades lysoPC, further confirm an interactive role for ACBP2 and lysoPL2 in overcoming Cd(II)-induced stress. © 2010 Landes Bioscience. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Landes Bioscience. The Journal's web site is located at http://www.landesbioscience.com/journals/psb | en_HK |
dc.relation.ispartof | Plant Signaling and Behavior | en_HK |
dc.subject | Acyl-CoA-binding protein | en_HK |
dc.subject | Cadmium | en_HK |
dc.subject | Hydrogen peroxide | en_HK |
dc.subject | Lysophospholipase | en_HK |
dc.subject | Oxidative stress | en_HK |
dc.title | Protein interactors of acyl-CoA-binding protein ACBP2 mediate cadmium tolerance in arabidopsis | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Xiao, S: xiaoshi@graduate.hku.hk | en_HK |
dc.identifier.email | Chye, ML: mlchye@hkucc.hku.hk | en_HK |
dc.identifier.authority | Xiao, S=rp00817 | en_HK |
dc.identifier.authority | Chye, ML=rp00687 | en_HK |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.4161/psb.5.8.12294 | - |
dc.identifier.pmid | 20657176 | - |
dc.identifier.pmcid | PMC3115187 | - |
dc.identifier.scopus | eid_2-s2.0-77957727621 | en_HK |
dc.identifier.hkuros | 182340 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77957727621&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 5 | en_HK |
dc.identifier.issue | 8 | en_HK |
dc.identifier.spage | 1025 | en_HK |
dc.identifier.epage | 1027 | en_HK |
dc.identifier.isi | WOS:000214008800024 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Gao, W=36045713300 | en_HK |
dc.identifier.scopusauthorid | Li, HY=51061323000 | en_HK |
dc.identifier.scopusauthorid | Xiao, S=7402022635 | en_HK |
dc.identifier.scopusauthorid | Chye, ML=7003905460 | en_HK |
dc.identifier.issnl | 1559-2316 | - |