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- Publisher Website: 10.1100/tsw.2009.12
- Scopus: eid_2-s2.0-63649123792
- PMID: 19219377
- WOS: WOS:000263381800006
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Article: Mature miR-184 and squamous cell carcinoma of the tongue
Title | Mature miR-184 and squamous cell carcinoma of the tongue |
---|---|
Authors | |
Keywords | MicroRNA Post-transcriptional regulators Squamous cell carcinoma Tongue cancer |
Issue Date | 2009 |
Publisher | The ScientificWorld Ltd. The Journal's web site is located at http://www.hindawi.com/journals/tswj/ |
Citation | TheScientificWorldJournal, 2009, v. 9, p. 130-132 How to Cite? |
Abstract | Human microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly. The data suggested that miR-184 is linked to the pathogenesis of tongue SCC. Further studies are warranted to evaluate the use of microRNA-based serological markers in monitoring tongue SCC. |
Persistent Identifier | http://hdl.handle.net/10722/125445 |
ISSN | 2013 Impact Factor: 1.219 2023 SCImago Journal Rankings: 0.526 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, TS | en_HK |
dc.contributor.author | Ho, WK | en_HK |
dc.contributor.author | Chan, JYW | en_HK |
dc.contributor.author | Ng, RWM | en_HK |
dc.contributor.author | Wei, WI | en_HK |
dc.date.accessioned | 2010-10-31T11:31:49Z | - |
dc.date.available | 2010-10-31T11:31:49Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | TheScientificWorldJournal, 2009, v. 9, p. 130-132 | en_HK |
dc.identifier.issn | 1537-744X | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/125445 | - |
dc.description.abstract | Human microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly. The data suggested that miR-184 is linked to the pathogenesis of tongue SCC. Further studies are warranted to evaluate the use of microRNA-based serological markers in monitoring tongue SCC. | - |
dc.language | eng | en_HK |
dc.publisher | The ScientificWorld Ltd. The Journal's web site is located at http://www.hindawi.com/journals/tswj/ | en_HK |
dc.relation.ispartof | TheScientificWorldJournal | en_HK |
dc.subject | MicroRNA | en_HK |
dc.subject | Post-transcriptional regulators | en_HK |
dc.subject | Squamous cell carcinoma | en_HK |
dc.subject | Tongue cancer | en_HK |
dc.subject.mesh | Carcinoma, Squamous Cell - genetics | - |
dc.subject.mesh | Gene Expression Regulation, Neoplastic | - |
dc.subject.mesh | Humans | - |
dc.subject.mesh | MicroRNAs - genetics - metabolism | - |
dc.subject.mesh | Tongue Neoplasms - genetics | - |
dc.title | Mature miR-184 and squamous cell carcinoma of the tongue | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Wong, TS: thiansze@graduate.hku.hk | en_HK |
dc.identifier.email | Chan, JYW: jywchan1@hku.hk | en_HK |
dc.identifier.email | Wei, WI: hrmswwi@hku.hk | en_HK |
dc.identifier.authority | Wong, TS=rp00478 | en_HK |
dc.identifier.authority | Chan, JYW=rp01314 | en_HK |
dc.identifier.authority | Wei, WI=rp00323 | en_HK |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1100/tsw.2009.12 | en_HK |
dc.identifier.pmid | 19219377 | - |
dc.identifier.scopus | eid_2-s2.0-63649123792 | en_HK |
dc.identifier.hkuros | 182405 | en_HK |
dc.identifier.hkuros | 176171 | - |
dc.identifier.hkuros | 154666 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-63649123792&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 9 | en_HK |
dc.identifier.spage | 130 | en_HK |
dc.identifier.epage | 132 | en_HK |
dc.identifier.isi | WOS:000263381800006 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Wong, TS=7403531328 | en_HK |
dc.identifier.scopusauthorid | Ho, WK=7402968844 | en_HK |
dc.identifier.scopusauthorid | Chan, JYW=27171772200 | en_HK |
dc.identifier.scopusauthorid | Ng, RWM=7102153861 | en_HK |
dc.identifier.scopusauthorid | Wei, WI=7403321552 | en_HK |
dc.identifier.citeulike | 4066613 | - |
dc.identifier.issnl | 1537-744X | - |