Signal-to-noise ratio of intraoperative tibial nerve somatosensory-evoked potentials

Abstract

To reveal the intrinsic signal-to-noise ratio (SNR) of single-trial somatosensory-evoked potentials (SEP). SEP was recorded from 13 scoliosis patients during surgery. The power of SEP was estimated with least-square fitting to obtain the most accurate value and then to estimate the SNR of every trial of SEP. The SNR of cortical SEP from 13 cases presented individual difference among each other. According to the mean and standard deviation, the coefficients of variation of cortical and subcortical SEP were 4.2% and 23%, respectively. The SNR of SEP was estimated to be -24 ± 1 dB in cortical SEP and -22 ± 5 dB in subcortical SEP. The lowest SNR of individual case was found to be -30 dB in cortical SEP and -53 dB in subcortical SEP. The results showed that SNR of intraoperative SEP recordings varies from person to person and presents a higher variability in subcortical than that in cortical, with a broad range from -53 to -5 dB. The results from this study can be used to understand the nature of SEP signals, which could guide researchers and designers on SEP denoising method selection, extraction, and measurement, as well as equipment development. © 2010 by the American Clinical Neurophysiology Society.