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Conference Paper: Interacting protein of granulin-epithelin precursor in liver cancer

TitleInteracting protein of granulin-epithelin precursor in liver cancer
Authors
KeywordsMedical sciences
Oncology
Issue Date2010
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 101st Annual Meeting of the American Association for Cancer Research (AACR 2010), Washington, DC., 17-21 April 2010. In Cancer Research, 2010, v. 70 n. 8 suppl. 1, abstract 3130 How to Cite?
AbstractBACKGROUND AND OBJECTIVE: Granulin-epithelin precursor (GEP), a novel growth factor, has been identified as a potential therapeutic target from our earlier genome-wide expression profile study on liver cancer. GEP over-expressed in liver cancer, and regulated proliferation, invasion and tumorigenesis. We demonstrated the therapeutic approach of GEP targeted therapy in human cancer using the home-made GEP monoclonal antibody on animal model, and GEP antibody showed dose-dependent inhibitory effect on tumor growth. However, the exact mechanism on how GEP executes its biological function, and in particular its interacting protein partners, is largely unknown. The present study aims to identify and characterize the GEP interacting protein ...
DescriptionThis journal suppl. entitled: Proceedings: AACR 101st Annual Meeting 2010...
Poster Presentations - Oncogenes: Membrane and Cytoplasm 1: abstract 3130
Persistent Identifierhttp://hdl.handle.net/10722/108286
ISSN
2023 Impact Factor: 12.5
2023 SCImago Journal Rankings: 3.468
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, CYen_HK
dc.contributor.authorPoon, TCWen_HK
dc.contributor.authorCheng, KCen_HK
dc.contributor.authorCheung, STen_HK
dc.date.accessioned2010-09-26T00:33:16Z-
dc.date.available2010-09-26T00:33:16Z-
dc.date.issued2010en_HK
dc.identifier.citationThe 101st Annual Meeting of the American Association for Cancer Research (AACR 2010), Washington, DC., 17-21 April 2010. In Cancer Research, 2010, v. 70 n. 8 suppl. 1, abstract 3130en_HK
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/108286-
dc.descriptionThis journal suppl. entitled: Proceedings: AACR 101st Annual Meeting 2010...-
dc.descriptionPoster Presentations - Oncogenes: Membrane and Cytoplasm 1: abstract 3130-
dc.description.abstractBACKGROUND AND OBJECTIVE: Granulin-epithelin precursor (GEP), a novel growth factor, has been identified as a potential therapeutic target from our earlier genome-wide expression profile study on liver cancer. GEP over-expressed in liver cancer, and regulated proliferation, invasion and tumorigenesis. We demonstrated the therapeutic approach of GEP targeted therapy in human cancer using the home-made GEP monoclonal antibody on animal model, and GEP antibody showed dose-dependent inhibitory effect on tumor growth. However, the exact mechanism on how GEP executes its biological function, and in particular its interacting protein partners, is largely unknown. The present study aims to identify and characterize the GEP interacting protein ...-
dc.languageengen_HK
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/-
dc.relation.ispartofCancer Researchen_HK
dc.subjectMedical sciences-
dc.subjectOncology-
dc.titleInteracting protein of granulin-epithelin precursor in liver canceren_HK
dc.typeConference_Paperen_HK
dc.identifier.emailCheung, ST: stcheung@hku.hken_HK
dc.identifier.authorityCheung, ST=rp00457en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1158/1538-7445.AM10-3130-
dc.identifier.hkuros170223en_HK
dc.identifier.volume70en_HK
dc.identifier.issue8 suppl. 1-
dc.identifier.isiWOS:000209823901092-
dc.publisher.placeUnited States-
dc.identifier.issnl0008-5472-

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