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Conference Paper: The abandonment of central executive? Fractionation of executive functions in patients with schizophrenia

TitleThe abandonment of central executive? Fractionation of executive functions in patients with schizophrenia
Authors
Issue Date2004
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
The 12th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 7-13 February 2004. In Schizophrenia Research, 2004, v. 67 n. 1 suppl., p. 243, abstract no. 517 How to Cite?
AbstractOBJECTIVE: The purpose of this study was to examine the phenomenon of fractionation of executive attention performance in schizophrenia. METHODS: A group of 90 schizophrenic patients (74 men, 16 women) were recruited. Patients were given a set of frontal executive function sensitive tests to assess initiation, sustained attention, switching and flexibility, impulsivity and disinhbition, strategy allocation and planning. They were also given information subscale and memory subtests of the WAIS-R and WMS-R. We analyzed individual patient’s executive attentional performance with the normative data from our laboratory. Summary scores for all specific executive attention components were computed. For each component, participants were classified as having impairment with their test performance below 1.5 standard deviations of the norms of the corresponding test. RESULTS: The findings showed that there were 27.8% (n = 25) cases demonstrated impaired performance in all executive components and 5.6% (n = 5) exhibited intact performance in all components. About 18.9% (n = 17), 16.7% (n = 15), 21.1% (n = 19), and 10% (n = 9) showed intact performance in 1 component, 2 components, 3 components, and 4 components, respectively. No significant differences were found among the groups in terms of education, gender, and duration of illness. Multiple univariate ANCOVA using age, information and medication as covariates indicated significant differences among the groups in terms of clinical symptoms and non-executive functions. CONCLUSION: These findings suggest there is a fractionation of central executive in this clinical group.
Persistent Identifierhttp://hdl.handle.net/10722/105484
ISSN
2023 Impact Factor: 3.6
2023 SCImago Journal Rankings: 1.374

 

DC FieldValueLanguage
dc.contributor.authorChan, RCKen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorCheung, EFCen_HK
dc.contributor.authorChen, RYLen_HK
dc.contributor.authorCheung, HKen_HK
dc.date.accessioned2010-09-25T22:36:02Z-
dc.date.available2010-09-25T22:36:02Z-
dc.date.issued2004en_HK
dc.identifier.citationThe 12th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 7-13 February 2004. In Schizophrenia Research, 2004, v. 67 n. 1 suppl., p. 243, abstract no. 517en_HK
dc.identifier.issn0920-9964en_HK
dc.identifier.urihttp://hdl.handle.net/10722/105484-
dc.description.abstractOBJECTIVE: The purpose of this study was to examine the phenomenon of fractionation of executive attention performance in schizophrenia. METHODS: A group of 90 schizophrenic patients (74 men, 16 women) were recruited. Patients were given a set of frontal executive function sensitive tests to assess initiation, sustained attention, switching and flexibility, impulsivity and disinhbition, strategy allocation and planning. They were also given information subscale and memory subtests of the WAIS-R and WMS-R. We analyzed individual patient’s executive attentional performance with the normative data from our laboratory. Summary scores for all specific executive attention components were computed. For each component, participants were classified as having impairment with their test performance below 1.5 standard deviations of the norms of the corresponding test. RESULTS: The findings showed that there were 27.8% (n = 25) cases demonstrated impaired performance in all executive components and 5.6% (n = 5) exhibited intact performance in all components. About 18.9% (n = 17), 16.7% (n = 15), 21.1% (n = 19), and 10% (n = 9) showed intact performance in 1 component, 2 components, 3 components, and 4 components, respectively. No significant differences were found among the groups in terms of education, gender, and duration of illness. Multiple univariate ANCOVA using age, information and medication as covariates indicated significant differences among the groups in terms of clinical symptoms and non-executive functions. CONCLUSION: These findings suggest there is a fractionation of central executive in this clinical group.-
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_HK
dc.relation.ispartofSchizophrenia Researchen_HK
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.en_HK
dc.titleThe abandonment of central executive? Fractionation of executive functions in patients with schizophreniaen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0920-9964&volume=67/1S&spage=243&epage=&date=2004&atitle=The+abandonment+of+central+executive?+Fractionation+of+executive+functions+in+patients+with+schizophreniaen_HK
dc.identifier.emailChan, RCK: ckrchan@graduate.hku.hken_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.emailCheung, EFC: cheungfc@ha.org.hken_HK
dc.identifier.emailChen, RYL: rylchen@hkucc.hku.hken_HK
dc.identifier.emailCheung, HK: cheung_hk@yahoo.comen_HK
dc.identifier.doi10.1016/j.schres.2003.10.001-
dc.identifier.hkuros88274en_HK
dc.identifier.volume67en_HK
dc.identifier.issue1 suppl.-
dc.identifier.spage243, abstract no. 517en_HK
dc.identifier.epage243, abstract no. 517-
dc.identifier.issnl0920-9964-

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