Collection View Count

Geo Map
Region#
AS - Asia67011
EU - Europe48857
NA - North America33691
AF - Africa9241
HKU - The University of Hong Kong4275
OC - Oceania3300
SA - South America85
UND - Undefined703
Total167163
Country#
CN - China36882
US - United States33399
GB - United Kingdom18528
IE - Ireland13759
SG - Singapore13352
KR - Republic of Korea7902
HK - Hong Kong7115
NL - Netherlands7014
ZA - South Africa6924
FR - France5619
OTH - Others16669
Total167163
City#
Dublin13702
Singapore13293
Beijing12601
Johannesburg6908
Ashburn5914
Amsterdam5424
London5020
The University of Hong Kong4275
Boydton3862
Sydney3151
Others93013
Total167163
PBL approach to teaching metabolism to B.Sc. Biochemistry students130
Roles of a novel splice variant of human IFI16 in innate immune response21
Towards remyelination therapy: derivation of oligodendrocyte precursor cells from bone marrow stromal cells33
Perlecan compartmentalizes collagen X in the mammalian growth plate140
Promoting deep learning in biochemistry by diversifying assessment strategies - experience at the University of Hong Kong77
Visualizing the Proteome Escherichia coli by Recombineering Technology91
Allelic variation of collagen IX as genetic predispositing factors for degenerative disc disease in Southern Chinese137
Activating ER-stress in differentiating osteocytes impairs maturation causing hyperostosis in mice168
Genetic and genomic analyses of chondrocyte adaptation to ER stress in vivo127
Emerging role of perineural chondroitin sulfates and semaphorin 3A in maturation of the central vestibular circuitry23
PRMT1 activates leukemic stem cell program in MLL-rearranged leukemia59
Investigating the effects of glucose levels on PDZD2 levels in rat insulinoma INS-1E cells24
Glycosaminoglycan composition of sciatic nerves of guinea pigs: effects of nerve crush87
Development of live recombinant salmonella oral vaccine against avian influenza viruses129
Impact of intracellular clearance of unfolded proteins on chondrocytes cell fate94
Construction of new DNA vectors based on promoters of Epstein-Barr Virus-encoded small RNAS for expression of small hairpin RNAS in mammalian cells83
Nitrogen Plasma Immersion Ion Implanted Nickel Titanium Alloys For Orthopedic Use97
Developmental plasticity of GABAergic synapses in medial vestibular nucleus of rats127
Reconstruction of the mouse Hoxb-3 gene expression pattern in transgenic mice108
Use of chondroitin sulphate lyases in combination for achieving maximal activity: implication for nerve regeneration85
Nucleic acid aptamers against aggrecanases: a novel method for Degenerative Disc Disease Therapy22
Fabrication and characterization of multi-channel chitosan nerve conduit and its potential application144
Kinesin-1 is necessary for chondrocyte cytokinesis173
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda88
Phylogenetic analysis of planarian collagens and their roles in regeneration30
Reconstitution of nucleus pulposus cell matrix niche in 3D collagen microsphere for mesenchymal stem cell discogenic differentiation51
Use of a bridge model to test the effect of neural glycosaminoglycans on regrowth of transected sciatic nerves in adult guinea pigs110
Deficiency of novel inhibitory neurotransmitter carbon monoxide in aganglionic bowel of Hirschsprung's disease.125
Use of tandem mass spectrometry as a tool for proteomics studies in aging and degeneration processes of the intervertebral disc136
BMI-1 negatively regulates JAK-STAT signaling in leukemia115
The role of hypoxia-inducible factor-1 in choroidal neovascularization92
Mechanism underlying fate commitment of human bone marrow stromal cells to Schwann cells30
Comparative analysis of bZIP transcription factors of the CREB3 subfamily111
Identification of novel serum metabolomic biomarkers related to the development of lumbar disc degeneration50
The Role of Chondroitin Sulfate Moieties on Cranial Motor Neuron Migration in the Developing Hindbrain of Rates90
Characterization of the specificity of Cre expression in cerebellar Purkinje cells97
sPDZD2: a novel negative modulator of hedgehog signaling40
Neuregulin 1 type III in the switch of bone marrow stromal cells to fate-committed Schwann cells37
Characterization of glycosaminoglycan-containing species synthesized by renal proximal tubular epithelial cells in culture88
Co-evolution of transcription factors and their binding sites108
Discovery and application of DNA aptamers which specifically bind and inhibit WWP1 ubiquitin ligase in the osteoblast53
Linkage analysis on familial early-onset degenerative disc disease (DDD)105
Roles of epstein-barr virus-encoded miR-BART microRNAs in nasopharyngeal epithelial tumorigenesis64
Phospho-JNK and phospho-jun are upregulated following hypoxic-ischaemic encephalopathy110
Defining the phenotype and molecular signatures of notochordal nucleus pulposus cells113
Transgenic mice expressing human epidermal growth factor show stunted growth76
Association of the cholesterol 24S-hydroxylase polymorphism with Alzheimer's disease in Chinese114
Development of heparin and heparan sulfate from recombinant syndecan-1 as a potential therapeutic for bronchiectasis93
Regulation of the tumour metastasis suppressor gene, NM23, by p21-activated protein kinase 5111
Roles and Regulation of MIPT3 in Interferon Signaling100
BAF250a-containing complex is required for secondary heart field development85
Neural-specific cis-acting and trans-acting regulation of the mouse Hoxb-3 gene during embryogenesis110
Acyl-CoA binding proteins from sunflower seeds58
Global landscape of histone modifications contributes to cellular identity determination by affecting gene expression dynamics43
Investigation of the lineage and tissue specificity of genes104
Histidine-rich protein, HPN and metallothionein: are they similar?116
The roles of Irx3 and Irx5 genes in inner ear sensorineural patterning30
IFI16β and STINGβ: negative regulators of innate immunity generated by alternative splicing54
Gli-mediated regulation of Sox9 in limb development45
Regulation of ubiquitination and degradation of CRTC1 transcriptional coactivator by salt-inducible kinase SIK138
Early postnatal disturbance of inhibitory transmission in the vestibular nucleus impacts on the thalamic spatial map and navigation behaviors36
Regulatory role of neuronal proheparanase in synaptic function of the central vestibular system139
Molecular and cellular consequences of Indian hedgehog mutations causing brachydactylies30
B Cell Development Defect in ZMPSTE24-/-Mice127
A Simple Novel Annular Puncture Model of Disc Degeneration in the Mouse Tail126
Genetic and genomic analyses of chondrocyte adaptation to ER stress134
A Novel Neural Response Algorithm for Protein Function Prediction137
In silico mapping of quantitative trait loci affecting bone mineral density in mice116
The Roles of CHOP and GADD34 in the Adaptation of Hypertrophic Chondrocytes to ER Stress90
Mesenchymal stromal cells rescue disc degeneration and function via suppression of fibrotic events59
The effects of cyclooxygenase -2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair90
Mapping of genetic modifier of congenital heart defects in type IIA procollagen deficient mice81
Understanding the molecular mechanisms of skeletal dysplasia through proteomics of mutant collagen X protein-expressing chondrocytes104
Characterization of human mesenchymal stem cells selected by collagen barrier94
Abnormal regulation of cartilage and bone growth in transgenic mice expressing mutant collagen X114
Epstein-Barr virus-encoded microRNA targets PUMA to promote tumor cell survival161
Peroxiredoxin-null yeast cells are hypersensitive to DNA-damaging agents79
Bismuth as an enzyme inhibitor: from antibacterium to antivirus140
Allogeneic mesenchymal stem cell transplanation into the intervertebral disc: effect of serverity of degernation and cell number on regeneratiion139
Decellularization of chondrocyte-encapsulated collagen microspheres114
Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs)94
Heparanse-syndecan-3 interaction in neurons of the adult spinal cord116
Development of an aptamer-based biosensing system for measuring luteinizing hormone pulsatility for infertility treatment26
Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation in osteoporosis spine127
A fast and accurate SNP detection algorithm for next-generation-sequencing data34
The function of kinesin-1 mediated intracellular transportation in long bone development135
The Regulatory Role of Heparanase in Synaptic Plasiticity at Hippocampus97
NRProF: Neural response based protein function prediction algorithm130
Abnormal chondrocyte differentiation in transgenic mice expressing a Schmid metaphyseal chondrodysplasia Col10a1 mutation143
ProteoMirExpress: inferring microRNA-centered regulatory networks from high-throughput proteomic and transcriptome data69
The regulation of FGF signaling by MT1-MMP in calvarial osteogenesis129
Epigenetic reprogramming of fibroblasts into osteo-chondroprogenitors120
Functional significance of the 3'-UTR in the mRNA of the stress-inducible protein CHOP/Gadd153101
Epigenetic dysregulation of leukemic Hox code in MLL-rearranged leukemia mouse model65
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation44
An Investigation of the Mutual Relationship between ER Stress and Oxidative Stress103
Understanding the biological role of UHRF130
Role of isthmin in chick spinal cord development41
Expression and Purification of Mutated hpn Protein, and Studies of Function of Cystein Residues in hpn93
Investigation of the Role of Kif5B in Pancreatic β-cells Function98
Mouse model with impaired collagen X degradation at the chondro-osseus junction115
Oxygen and sodium plasma-implanted nickel-titanium shape memory alloy: a novel method to promote hydroxyapatite formation and suppress nickel leaching149
Induction of osteo-chondroprogenitors formation during transcription factor-mediated reprogramming processes43
The role of Sox2 and Sox18 in hair cycle and specification137
Loss of yeast peroxiredoxin TSA1 induces genome instability through constitutive activation of DNA damage checkpoint and elevation of cellular dNTP levels102
Chinese patients with rasopathies: Detection of 29 known and novel variants using next-generation sequencing (NGS)62
DNA aptamers for molecular recognition in medical diagnostics32
Genetic Variations of the Cholesterol Metabolism Pathway Genes and the risk of Alzheimer's Disease82
Investigating the function of SOX9 in development82
In vivo analysis of the transactivation specificity of group E SOX proteins166
Phenotypic changes of stem cells after culture in the intervertebral disc niche41
How Has Genetics Changed Our Understanding of Disc Degeneration?142
In vivo analysis of the transactivation specificity of group E SOX proteins101
Mutations of SOX10 gene in Hirschsprung's disease patients with and without Waardenburg-Shah Syndrome112
The role of MT1-MMP in regulating lineage progression of chondrocytes130
Semaphorin 3A and chondroitin sulphate proteoglycan networks of perineuronal nets regulate the developing central vestibular circuitry34
Dysregulation of Aqp3 and endolymphatic hydrops in a mouse model of campomelic dysplasia56
Studying the roles of mouse Sox10 in Schwann cell development and Wallerian degeneration.113
ProF: neural response based protein function prediction algorithm99
Mapping of chondroitin sulfate glycoform and chondroitin 6-sulfotransferase in neuroepithelial boundaries of mouse embryos100
Mutations in collagen IX as genetic predisposing factors for degenerative disc disease in Southern Chinese124
Engineering tumor targeting salmonella116
Functions of suppressor of fused (Su(fu)) in mammalian midbrain and hindbrain neurogenesis100
Formation of CAPO4 and Suppression of Ni Leaching in Nitinol Using Oxygen and Sodium Plasma Immersion Ion Implantation165
Different mutations in sedlin cause X-linked spondyloepiphyseal dysplasia tarda via two distinct mechanisms: protein misfolding and protein-protein interaction Abrogation63
The engagement of glutamate and GABA receptors in central vestibular synapses for developmental acquisition of spatial recognition32
Tax-induced recruitment of TORC family coactivators is required for transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats114
Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres97
Tax-induced recruitment of TORC family coactivators is required for transcriptional activation of HTLV-I LTR102
The role of Irx3/5 in regulating lineage progression of hypertrophic chondrocyte to osteoblasts38
Targeted disruption of the mouse type X collagen gene111
FaSD: a efficient model to detect SNPs for NGS data35
Expression of heparanase and syndecan-3 are colocalized in mouse growth plate82
Alleviating ER stress in chondrocytes: survival strategies with double-edged developmental consequences122
Upregulation of NF-kB signaling pathway in hepatocellular carcinoma129
Sufu and Gli3 repressor mediate the temporal basal-to-apical progression of hair cell differentiation in mammalian cochleae30
Association of the asporin D14 allele with lumbar disc degeneration173
In vitro and in vivo studies of perineuronal glycosaminoglycans in synaptic functions85
Ectopic expression of Hoxb3 in otic vesicle causes abnormal ear development110
In vitro selection of DNA aptamers binding H5N1 Virus nucleoprotein96
Intervening intervertebral disc degeneration by small molecules that positively modulate proteoglycan production43
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H103
Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat92
Developmental Genomics and Skeletal Research99
Psr1p interacts with SUN/sad1p and EB1/mal3p to establish the bipolar spindle 49
Mechanistic study of salmonella-induced reduction of cancer metastasis42
The liver-enriched transcription factor creb-H is a growth suppressor under-expressed in hepatocellular carcinoma103
Epstein-Barr virus encodes an antiapoptotic microRNA to inhibit PUMA and promote tumor cell survival87
Anterior/Posterior-specific Properties of Adult Spinal Cord Neural Progenitor Cells123
Abnormal chondrocyte differentiation and chondrodysplasia in transgenic mice177
Association of Asporin D14 allele with lumber disc degeneration in asians140
Notch signaling in differentiation of bone marrow-derived Schwann cells31
Secretin is widely expressed during mouse embryonic development145
Towards aptamer-mediated malaria diagnostics: structural insight into discriminatory molecular recognition by a DNA aptamer56
Identification and characterization of TXBP151, a novel cellular target of HTLV-ITAX100
Increased vulnerability to liver injury is associated with decreased mitochondrial activities in adiponectin knockout mice: potential roles of UCP2 in the hepatoprotective functions of adiponectin99
miR-BART5 is an anti-apoptotic miRNA encoded by EBV and inhibits PUMA to promote host cell survival85
Utility of Hoxb2 enhancer - mediated Cre activity for functional studies in the developing inner ear98
Developmental modulation of long-term plasticity at vestibular GABAergic synapses73
Role of matrix remodeling in endochondral bone formation90
In vivo plasticity in terminal differentiation of hypertrophic chondrocytes induced by ER stress.115
KGG: a systematic biological knowledge-based mining system for genome-wide genetic studies134
The restrictive role of chondroitin sulfate moieties on the lateral migration of trigeminal motor neurons during hindbrain development in rats156
Prelamin A Regulates DNA Repair and Senescence via Histone Modifications78
Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma146
Correlation between the Compressive Macro-mechanical Properties of the Human Nucleus Pulposus and the Nano Structure of its Individual Collagen Fibrils104
Roles of yeast peroxiredoxins in cellular defence against DNA damage118
Abnormal chondrocyte differentiation in COL2A1-SV40 T-antigen chimeric mice135
Genetic variation in the Col9A2 gene and its association to intervertebral disc abnormalities in Southern Chinese149
A characterisation of the cellular toxicity induced by manganese137
Development Of Three-Dimensional System For Culturing Notochordal Cells50
Association between genetic polymorphisms and periodontitis In Hong Kong Population92
Assessment of next generation sequencing analysis tools shows lower coverage and poorer SNP-calling quality in the CpG islands and regulatory regions35
Phosphotransferase activity of bone alkaline phosphatase under physiological pH68
Expression of chondroitin sulfotransfgerases in relation to cranial motor neuron migration94
Context dependent impact of Sox9 campomelic dysplasia mutation79
Post-translational regulation of Sox9 in neural crest delamination69
Type IIA Procollagen: A Regulator of Nodal Signaling109
Heparanase expression in neurons and Schwann cells that emigrated from dorsal root ganglion explants in culture106
Prelamin A regulates DNA repair through histone modifications91
Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vivo study with peripheral nerve conduits137
ER stress in the growth plate89
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP cellular levels108
dbPSHP: a database of recent positive selection across human population47
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans42
Sulfated maltoheptaose reduces neutrophilic airway inflammation in a smoking rat model of chronic obstructive pulmonary disease122
Chondroitin sulfate proteoglycans produced by astrocytes modulate neuron adhesion and neurite outgrowth97
Fabrication and evaluation of chitosan devices for peripheral nerve regeneration: An initial study123
Perturbed SUFU-GLI-SOX10 regulatory network underlies defective enteric nervous system development and Hirschsprung disease66
Perinatal perturbation of NMDA receptor in the vestibular nucleus attenuates cerebellar function99
Derivation of human neural crest stem cells from human induced pluripotent stem cells40
Signal transduction mechanisms regulating transferin receptor gene expression during phorbol ester-induced human leukemic HK-60 cells140
Chondroitinase ABC isoforms cooperate to enhance axonal growth90
Generation of induced pluripotent stem (iPS) cells from bone-forming cells109
FaSD: a fast and accurate SNP detection algorithm for next-generation sequencing data94
A mutant gA-crystallin leads to cataractogenesis through the unfolded protein response108
The inhibitory effects of siRNAS targeting the replicase or structural genes of the sars-associated coronavirus (SCOV) on viral replication116
Determination of protein biomarkers by microflow injection aptamer-coated piezoelectric quartz crystal biosensor52
The Over-expression of Bcl-2 antagonizes the pro-apoptotic function of the Kappa-Opioid receptor129
A Systematic and Simple Scoring System for Histological Analysis of the Mouse Intervertebral Disc during Natural Ageing, Degeneration, and Regeneration69
Assessment of next generation sequencing analysis tools shows lower coverage and poorer SNP-calling quality in the CpG islands and regulatory regions in cancer genome88
A fast and accurate SNP detection algorithm for next-generation sequencing data42
Mitotic checkpoint control through phosphorylation and degradation79
The molecular and cellular changes underlying increased bone formation in a mouse model with generalized progressive hyperostosis100
The growth plate abnormality in transgenic mice expressing type X collagen with a mutation in the NCI domain in dosage dependent103
Over-expression of Hoxb3 affects sensory neuron differentiation and inner ear morphogenesis119
Role of heparanase in synaptic plasticity at the hippocampus and the vestibular nucleus116
Collagen X function and regulation of gene expression145
Three dimensional culture and chondrogenic differentiation of mouse embryonic stem cells84
Preparations of Chitosan Support for Cultures of Schwann Cells and Transdifferentiated Mesenchymal Stem Cells96
Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract131
Structural and functional relationship of adiponectin as an anti-aging hormone89
Use of chondroitin sulphate exolyase and endolyase to decrease axon-restrictive chondroitin sulphates in neural environments103
UHRF1 regulated hair follicle stem cells self-renewal32
The disaccharide composition of heparan sulfates that upregulate regenetation of post-traumatic sciatic nerves of adult guinea pigs77
The relationship of p85 and the apoptotic signalling of N-(4-hydroxyphenyl)retinamide (4HPR)82
Chondroitin sulfates restrict axonal growth along the projection path of vestibular nuclear (VN) neurons across the hindbrain of prenatal rats129
Evidence for physical interaction between CHOP/Gadd153 mRNA and specific intracellular proteins92
Migration of mesenchymal stem cells to injured spinal cord through interaction of SDF-1/ CXCR4167
Perturbation of GABAergic synapses in the vestibular nucleus during a postnatal critical period impacts on the acquisition on spatial recognition61
Calcium oxalate crystallizing properties of macromolecules released by renal tubular cells in vitro137
ChIP-array: combinatory analysis of ChIP-seq/chip and microarray gene expression data140
Semaphorin3A, associated with perineuronal nets, regulates the development of the maturation of the central vestibular circuitry18
Inferring gene regulatory network from variable delay high temporal data93
Profile of pro-inflammatory cytokines in bronchiectasis109
Isthmin and its relation to FGF signalling during chick embryonic development29
Sirt1, end of the story in aging?30
Abnormalities in fracture healing in the absence of collagen type X100
A vagal neural crest specific enhancer for establishing transgenic mouse models112
Genetic and epigenetic alterations on DLC-1 gene in hepatocellular carcinoma118
Hoxb3 mutation leads to interleukin-6 dependent plasmacytoma103
Novel function of HOXB3 gene in regulation B lymphopoiesis80
Towards myelin and functional recovery in the injured CNS: derivation of oligodendrocyte precursor cells from adult bone marrow stromal cells102
Chondroitin sulfotransferase expression pattern for the regulation of cranial motor neuron migration in rat embryonic hindbrain64
Role of fibrogenesis in control of disc degeneration55
Mannose binding lectin and autoimmune disease103
Altered Sox10 gene expression in aganglionic bowel of Hirschsprung's disease patients104
Molecular and developmental insights into the pathogenesis of the SOX9Y440X campomelic dysplasia mutation107
Functions of epidermal growth factor revealed by analysis of transgenic mice113
Early postnatal perturbation of inhibitory transmission in the vestibular nucleus governs the expression of spatial map and spatial navigation behaviors31
Cloning and characterizing PAC1 receptor-Hop1 splice variant in goldfish (Carrasius auratus)108
Guidance of DRG neurons in fate determination of bone marrow derived Schwann cells52
Delivery of SCV helicase aptamers using cationic lipidic systems134
Smad4 pathway inhibits sensory formation in the mouse cochlea26
The role of Uhrfl in hedgehong signaling30
Development of nucleic acid aptamers against Plasmodium falciparum lactate dehydrogenase for improving the diagnosis of malaria105
Effects of down-regulating hypoxia-inducible factor-1 alpha on retinal pigment epithelial cells under hypoxia103
Expression of chondroitin sulfotransferase in cranial motor neurons for cell migration in rat embryonic hindbrain17
Genes and Diseases: Basic Concepts128
Dual-functional encapsulated-cell therapy implant for retinal diseases: sustained intraocular GDNF delivery and controlled termination30
Glycosaminoglycans elaborated by astrocytes in serum-containing culture101
Targeted Inactivation of KIF5B in Pancreatic β-Cells Leads to Insulin Secretory Deficiency and Increased β-Cell Mass in vivo84
Viral suppression of innate antiviral response through PACT targeting18
The Hong Kong Genome Wide Association Study: How should we move forward?20
The fission yeast TACC homolog alp7 is recruited to the spindle pole for bipolar spindle formation 48
Differential and overlapping expression of SOX2 and SOX9 in inner ear development105
Construction of nerve guidance channel with use of Schwann cell seeded aligned chitosan nanofibers46
Osteoprotegerin (OPG) and interleukin-1 beta (il-1b) gene polymorphisms are associated with knee osteoarthritis in Chinese127
Recent progress in the study of the intracellular functions of diadenosine polyphosphates300
Molecular basis for increased bone formation in a mouse model expressing mutant type X96
Novel role of proheparanase in regulating synaptic function in the central vestibular circuitry60
The role of farnesyltransferase inhibitor in the treatment of Hutchinson Gilford progeria syndrome88
Prostate Cancer Growth Modulation By sPDZD2108
Rabbit articular cartilage repair using collagen-mesenchymal stem cell microspheres81
Transgenic mouse models of human skeletal disorders92
BAF250a is required for secondary heart field development109
Intracellular transportation in diseases and development94
Understanding the contribution of Lgr5+ interzone progenitor cells in joint repair46
Inorganic polyphosphate as a forgotten molecule in osteoblasts: from synthesis to function39
Inorganic polyphosphate triggers interleukin 11 production in osteoblasts cell signalling52
Kinesin-1 is involved in chondrocytes adhesion to extracellular matrix and motility60
Expression and purification of mutated hpn protein, and studies of function of cysteine residues in hpn143
Genome-wide association study of Degenerative Disc Disease (DDD)170
Postnatal refinement of gravity-related spatial coding to the central vestibular circuitry149
Ectopic Hoxb-3 expression causes cranial ganglial nerve and pharyngeal arch defects and leads to transformation of vertebrae89
A hypothesis for the function of collagen X112
Over-representation pattern of SNPs in the genome of restless legs syndrome samples81
Roles of a novel splice variant of human IFI16 in innate immune response36
Herpes simplex virus type 1 Us11 protein inhibits type I interferon production by suppressing PACT induced activation of RIG-I39
Suppressor of fused (Su(fu)) modulates hindbrain hedgehog signaling and neurogenesis81
Change in the composition of perineuronal nets of central vestibular neurons following unilateral labyrinthectomy94
Structure of RPA32 bound to SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins28
Understanding the molecular impact of Sox9Y440X in campomelic dysplasia47
The molecular and cellular changes underlying increased bone formation in a mouse model with generalized progressive hyperostosis120
Identifying the DNA binding specificity of Hoxb-3101
Genetic Analyses of Terminal Differentiation of Hypertrophic Chondrocytes98
Differential effects of chondroitin and heparan sulfates on post-traumatic regrowth in sciatic nerves of adult guinea pigs74
Involvement of perineuronal nets in developmental plasticity of the central vestibular system83
Molecular consequences of Indian Hedgehog mutations causing brachydactylies in chick neural tube102
Investigation of Cardiovascular Defects in a Mouse Mutant HOXB3LACZ107
Expression of heparanase 1 and heparanase 2 at the hippocampus36
An EBV microRNA targets DICE1 tumor suppressor gene27
Study of aptamer selection methodologies for developing piezoelectric quartz crystal biosensors to detect microalbuminaria, malaria and SARS biomarkers50
Aged-related degeneration of lumbar intervertebral discs in rabbits revealed by deuterium oxide-assisted MRI107
The regulatory role of perineuronal nets in postnatal maturation of vestibular behavior system26
DNA Aptamer selection and cellular delivery for the inhibition of E3 Ubiquitin Ligase WWP1118
The Mechanisms of Chondroitin Sulphate Lyases Treatment in Promotion of Axonal Growth160
Protective effects of Chinese Medicine salvianolic acid B, astragaloside IV, and daillyl trisulfide on endothelial cells against damage induced by H2O299
Upregulation of chondroitin 6-sulfotransferase (C6ST) in rat sciatic nerves after crush-injury93
Expression of the a1(II) collagen gene during early mouse embryogenesis89
Effect of lithium and myo-inositol on the time courses of changes in inositol trisphosphate and free calcium concentrations in K opioid agonist-stimulated rat ventricular myocytes (Abstract)93
Premature aging and genomic instability in mice lacking zmpste24104
Identifying small molecules for regulating proteoglycan metabolism in cartilaginous tissues28
Bioinformatic studies of gene regulation involving SOX9 and the SOX family131
Role of heparanase 1 and heparanase 2 in modulating synaptic activities74
Identification of a potential auto-regulatory site upstream of the mouse Hoxb-3 gene103
Hyaluronan is identified in urine of renal stone formers122
LKB1 tumor suppressor is a negative regulator of Tax-mediated transcriptional activation of human T-cell leukemia virus type 1 long terminal repeats90
The role/s of type IIA procollagen in BMP (Bone morphogenetic protein) signaling.82
Identification of sclerostin interacting partners: steps towards Osteoporosis Therapy with aptamer-based inhibitors199
Chondroitinases ABC I and II from Proteus Vulgaris for Therapuetic Use: Cloning and Characterization116
Identification and characterization of a novel interaction partner of centrosomal coiled-coil protein TAX1BP290
Engineering Tumor-killing Salmonella against Breast Cancer122
Terminable cell-based GDNF delivery device for intravitreal applications85
Association of chromosome 6p multiple regions with nasopharyngeal carcinoma and gene expression changes in cancer tissue98
Changes in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury111
EATdb: a database of human enhancers and their putative targets133
Modulating proteoglycan metabolism using small molecules as treatment for disc degeneratioin87
Linkage analysis with subsequent fine-mapping on familial early onset-degenerative disc disease.122
PDZD2, a candidate gene for brachydactyly type A1, encodes a secreted protein that negatively modulates hedgehog signaling32
The role of endocannabinoid in long-term plasticity of vestibular GABAergic synapses and behavioral outcome in developing rats35
Prediction of lumbar spinal stenosis in Chinese: findings from a genome-wide association study51
Regulation of gene transcription by NF-kB and stats downstream of the ret receptor tyrosinekinase in hirschsprung disease and thyroid cancer95
Coagulopathy after donor-hepatectomy: implications for postoperative analgesia169
Functional Analyses of Type II Procollagen in Mouse Inner Ear Development81
Roles of Kinesin-1 mediated intracellular transport in skeletal development39
Growth-inhibitory and facilitatory aspects of chondroitin sulfates in developing neural environments113
Protein tyrosine phosphatase non-receptor 21 (PTPN21) contributes to Elk-1 dependent NRG3 transcription in mice cortical neuron model61
EPS8 and FOXM1 - Do they mesh to promote carcinogenesis?88
Expression of HoxB-3 in the anterior neural domains depends on other Hox genes92
Unraveling the role of type X collagen during fracture repair83
Epigenetic silencing of miR-203 is a disease initiation event of multiple myeloma109
Influenza A virus NS1 protein suppresses innate antiviral immune response by preventing PACT-induced activation of RIG-I31
The involvement of perineuronal semaphoring 3A and chondroitin sulfates in regulating maturation of the central vestibular circuitry103
Cadherin 2 is required for intervertebral disc homeostasis and maintenance of vacuolated phenotype in nucleus pulposus cells100
Formation of new patterns by programming cell motility33
Screening small molecule ihibitors against proteoglycan degradation to control tissue degeneration74
Varying expression of chondroitin sulfotransferases for cranial motor neuron migration in rat hindbrain development36
Identification and characterization of long-range SOX9 enhancers in limb development134
Group I p21-activated kinases are required for optimal activation of human T cell leukemia virus type 1 long terminal repeats by viral oncoprotein tax111
Human T-cell leukemia virus oncoprotein Tax represses nuclear receptor signaling by targeting transcriptional coactivator TXBP151108
Interaction of deleted in liver cancer 1 (DLC1) with tensin2 and its implications in tumor suppression126
Properties and potential applications of enteric neural crest stem cells from mouse embryonic gut114
The Role of Sox 10 in Mouse Inner Ear Development113
MAD2 expression induces chemosensitization to DNA damaging agent, cisplatin, in nasopharyngeal carcinoma cells104
Dysregulation of mitotic spindle checkpoint control in hepatocellular carcinomas111
Ectopic expression of Hoxb3 in the second branchial arch leads to abnormal craniofacial development138
Cell-to-cell spreading of RNA interference in mammalian cells104
Sox10 mutation affects gliogenesis of the cochleo-vestibular ganglion in mouse inner ear development95
Characterization of novel putative tumor suppressor gene, DLC2 (deleted in liver cancer 2), in hepatocellular carcinoma108
Functional Study of Heparanase in the explant cultures of rat dorsal root ganglia106
Effects of chondroitin sulfate supplements on regeneration of bridged sciatic nerves98
Protein and Gene Expression Profiles of the Intervertebral Disc107
Enhanced corrosion resistance and biocompatibility by plasma implantation of nickel titanium alloys: an in vitro and surface chemical study134
Disruption of the mouse Hoxb3 locus affects ventral body wall development94
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation38
Identification and characterization of a novel liver-enriched transcription factor of the BZIP family88
A genetic approach for disease gene discovery in the mouse131
Integration of pathways mediating chondrocyte adaptation to ER stress in VIVO93
Perineuronal chondroitin sulfates regulate vestibular plasticity during development44
Similarities and differences in apoptosis induced by staurosporine and wortmannin101
Sox10 mutation affects enteric neural crest cell migration100
An Emerging Role of Notch Signaling in the Switch to Fate Commitment of Bone Marrow-Derived Schwann Cells38
Loss of MT1-MMP influences CNS development122
Type X collagen NC1 mutations produced by site-directed mutagenesis prevent in vitro assembly99
Uncoupling protein-2 mediates neuronal survival by leptin against mitochondria dysfunction and ATP deficiency120
Expression of homeobox gene HoxB5 is localized in the ganglia of human fetal and infant guts but not in Hirschsprung's disease gut251
Generation of induced pluripotent stem (iPS) cells from bone forming cells101
A centrosomal target of human T-cell leukemia virus type I oncoprotein Tax on the road to genome instability121
Studies of oxalate transport across filter cultures of renal proximal tubular epithelial cells88
Circling, deafness and yellow coat displayed by chromosome 3 mouse mutants yellow submarien (Ysb) and light coat and circling (Lcc)100
Irx3 and Irx5 regulate cochlear hair cell specification and differentiation37
Are There Protective Genes for Disc Degeneration?58
Derivation of oligodendrocyte precursor cells from bone marrow stromal cells for remyelination therapy57
Abnormal chondrocyte differentiation is dosage-dependent in transgenic mice expressing unassembled mutant collagen X in hypertrophic chondrocytes134
Association between FCGR3A polymorphisms and periodontitis in Hong Kong Chinese110
Cell fate determination in skeletal development and growth105
Use of Schwann cell-seeded nanofiber as nerve conduit70
The use of small molecules to direct the differentiation of embryonic stem cells into insulin-secreting β-like cells150
Cell to cell spreading of RNAi in mammalian cell94
Sox2 regulates hair type specification and pigmentation32
Migration of mesenchymal stem cells to injured spinal cord through interaction of SDF-1/CXCR490
Postnatal developmental profile of otolith-related inferior olivary neurons in rats24
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice160
Visualizing the Proteome Escherichia coli by Recombineering Technology90
The genetics of SELEX51
Exchange protein directly activated by cAMP 1 is involved in β3-adreneric induction of brown adipose tissue in white adipose tissue741
Development of a trans-kingdom expression system in cancer therapy106
DNA methylation status influences expression of human neuroglobin gene98
Aberrant Kruppel-like factor 4 expression causes proliferation defect in Patched1-/- neural crest cells243
Understanding Molecular Mechanism of Laminopathy-based Premature Ageing94
Modifications in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury96
An aptamer-based piezoelectric crystal biosensor for SARS coronavirus helicase50
Mechanistic insights into chondrodysplasia caused by ER-stress revealed by genetic and transcriptome analyses124
Suppression of type I interferon production by human T-cell leukemia virus type 1 Tax oncoprotein36
Genomic Instability in Laminopathy-based Premature Aging147
Suppressor of fused (Su(fu)) functions upstream of notch pathway and plays domain specific function in orchestrating the maintenance and differentiation of hindbrain neural progenitor pools66
Sox10 is essential for gliogenesis of the cochleo-vestibular ganglion103
MMP14 regulates the lineage progression of hypertrophic chondrocytes40
Mesenchymal stem cells based osteochondral tissue engineering45
Differential and overlapping expression of SOX2 and SOX9 in inner ear development108
Proheparanase-mediated AMPA-type glutamate receptor regulation in synaptic plasticity86
Limiting histone ubiquitylation selectively promotes homologous recombination DNA repair31
Maturation profile of ionotropic glutamate receptors in central vestibular neurons of rats89
The epstein-Barr virus encoded latent membrane protein-1 protects cells against caspase-independent apoptosis90
Salvianoli acid B inhibits hydrogen peroxide -induced endothelial cell apoptosis through regulating P13K/Akt signaling90
A histological grading system for evaluating disc degeneration in the mouse84
miR-BART5 is an anti-apoptotic miRNA encoded by EBV and inhibits PUMA to promote host cell survival122
A novel non-turing mechanism of spot pattern formation40
Characterization of a Sox10 mouse mutant generated by gene targeting141
An in-vitro and surface chemical analysis of nickel-titanium alloys enhanced by plasma ion implantations surface treatment99
Heparan sulfates upregulate regeneration of transected sciatic nerves of adult guinea pigs230
Heparanase expression in Schwann cells as revealed in injured sciatic nerves and dorsal root ganglion explant culture102
The induction of p21/WAF1/CIP1 expression by the specific kappa opioid receptor agonist is independent of MAPK and PKC81
Confronting the challenges of biochemistry teaching and learning in the medical curriculum40
Spatiotemporal expression of chondroitin 6-sulfotransferase (C6ST) in regeneration of crush-injured sciatic nerves of adult rats87
Dosage-dependent requirement of sedlin component of the TRAPP complex in mouse embryonic development62
Unfolded protein response leading to cataractogenesis in a microphthalmia cataract mouse mutant171
The upregulation of GADD153 expression and N-(4-hydroxyphenyl)retinamide (4HPR)-induced apoptosis87
Molecular and developmental insights into the pathogenesis of the Sox9Y44X campomelic dysplasia mutation79
Changes in Perineuronal Nets within the Rat Vestibular Nuclei during Postnatal Development and in Injury128
Down-regulation of two novel genes by hypoxic-ischaemic encephalopathy in neonatal mouse127
Dysregulation of mitotic spindle checkpoint control in hepatocellular carcinomas99
Genomic Analysis of Increased Osteoblast Activity in a Mouse with generalized Hyperostosis77
Heparanase activity enhances MMP-7 dependent syndecan-1 shedding in the airway34
Loss of β-catenin in hypertrophic chondrocytes affects trabecular bone formation28
Toward exploring pluripotency landscape through light-induced tuning of Oct4 expression36
Accelerated Senescence in Degenerate Intervertebral Disc of Laminopathy-based Premature Aging Mouse Model151
Regulation of the mouse Hoxb-3 gene in the mindbrain130
Functional Analysis of the Mouse Isthmin Gene Encoding a Novel Secreted Protein132
Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development75
Development of an effective method to tag escherichia coli chromosomal genes based on recombineering80
Chondroitin sulfates enriched in the developing rat hindbrain restrict commissural projections of vestibular neurons127
Interaction of Hoxb3 and Hoxb1 in hindbrain patterning revealed by ectopic expression of Hoxb3 in rhombomere 495
Identification of regulatory elements directing control of Sox2 expression in mouse inner ear development94
Structure of RPA32 with N-terminus of SMARCAL1 reveals a consensus structural motif shared by RPA32 interacting proteins29
Genome-wide association study of Degenerative Disc Disease (DDD)128
Proheparanase and AMPA receptor trafficking in synaptic plasticity99
Gene and Protein Expression Profiles of the Intervertebral Disc: In Health and Disease - A General Overview87
Fusion of cranial ganglia cuased by the ectopic expression of Hoxb-3 gene in transgenic mice129
Chromatin remodelling regulated by nuclear lamins in DNA repair and accelerated aging78
Insights into the molecular pathogenesis of Campomelic dysplasia caused by mutations in SOX9106
Epigenetic reprogramming of fibroblasts into osteo-chondroprogenitors119
The role of Sox genes in inner ear development64
Abnormal chondroctye differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia Col10al mutation135
identification of GTPase activating protein (GAP) specific for Rab27a109
Linkage analysis with subsequent fine-mapping on familial early-onset degenerative disc disease123
Galactosemia and rat granulosa cell apoptosis109
Krüppel-like factor 4 (KLF4) in neuroblastoma101
Sox10 regulates enteric neural crest cell migration in the developing gut105
Stimulation of the k-receptor in cultured cardiomyoblast produced different combinations of intracellular signals at low and high concentrations of specific k-agonists86
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail36
The role of cyclooxygenase 1 and 2 in fracture healing100
Regulation of FOXM1c by the Raf/MEK/MAPK pathway116
Chondroitin sulfates restrict axonal growth along the projection path of VN neurons across the hindbrain of prenatal Sprague-Dawley rats129
Mechanism study on two DNA repair systems76
An insertional mutation affecting coat colour and vestibular function in mice80
Chitosan nanofiber composed nerve conduit for directing axonal growth21
Dual roles of Sox9 in transcriptional regulation in proliferating chondrocytes113
In vivo study of asporin, a genetic risk factor for intervertebral disc degeneration94
Chondroitinase ABC promotes axonal regrowth of Clarke's neurons into peripheral nerve graft after hemisection of the spinal cord105
MOOCs in Postmodern Asia - Session: Technology-accelerated Learning in the West35
Systematic analysis of the role of transcription regulators in distal interactions24
Recombinant expression and characterization of chondroitinse ABC I and II85
Human COL2A1-directed SV40 T-antigen expression in transgenic mice results in abnormal skeletal development101
The roles of Hoxb3 and Jag1 in mediating branchial arch defects in Six1-Eya1 associated Branchio-Oto-Renal Syndrome38
Studying the role of epidermal growth factor in chondrogenesis133
Deregulation of Cybb prevents myeloid differentiation in Mll-Een Leukemia Cell30
Human TRBP and PACT directly interact with each other and form a complex with Dicer to promote the production of small interfering RNA88
Upregulated proteoglycans synthesis in a human colon cancer cell line treated by hexamethylene bisacetamide96
The role of PERK pathway in adaptation of hypertrophic chondrocytes to ER stress139
Mesenchymal stem cells mediate disk regeneration by suppression of fibrosis in nucleus pulposus181
Sensorineural deafness in a mouse model of campomelic dysplasia88
Genome wide linkage association analysis reveals PTPN21 contributes to Elk-1 dependent NRG3 expression, enhances neuronal survival in embryonic cortical neurons41
Role of autophagy in chondrocyte differentiation30
Epigenetic control of DNA repair in premature ageing92
Differential protein profiling of stressed chondrocytes and skeletal dysplasia disease108
The effects of chondroitinase ABC digestion products on neurite growth: saccharide length and sulphation pattern29
Differentiation of notochordal-like cells from human pluripotent stem cells126
Ex Vivo Generation of Myelinating Schwann-cell Like Cells from Bone Marrow-derived Neurospheres109
Investigation of the protein/polyphosphate binding interface: mutational studies on mycobacterium tuberculosis polyphosphate kinase 2 (PPK2)33
Activation of TORCI transcriptional coactivator through MEKKI-induced phosphorylation and ubiquitination82
Cell-specific expression of Cre recombinase in Purkinje and retinal bipolar neurons99
Chondroitin sulfate moieties control motor neuron migration in the rat embryonic hindbrain45
The role of nuclear membrane-type matrix metalloproteinase I (MT1-MMP) in cancer28
Functional roles for Irx3 and Irx5 in skeletal development36
DNA aptamers selected for the inhibition of E3 ubiquitin ligase WWP129
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail43
Understanding the biological role of isthmin during mouse development and homeostasis46
The role of Sox10 in enteric neural crest cell migration78
Functional characterization of SOX10 mutations for understanding the molecular pathogenesis of Waardenburg-Hirschsprung syndrome91
The up-regulation of GADD153 expression in human epithelial tumor cells treated with N-(4-hydroxyphenyl)retinamide (4HPR)93
Visualizing becterial proteomes99
Novel sequence motif regulates pluripotency48
Identification of 3' splicing variants of receptor tyrosine kinase encoding gene RET in mouse and expression study of RET splicing variants in developing mouse embryo139
Diagnosing malaria using DNA aptamers against P. falciparum LDH23
Bioinformatics-aided discovery of transcriptional regulators of chondrocyte differentiation in the growth plate54
A discriminatory DNA aptamer for malaria diagnostics from the blind watchmaker27
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family96
Unraveling the molecular basis of the bacteriophage lambda-encoded recombination system in E. coli102
Glutamatergic transmission in the vestibular nucleus is critical to the formation of spatial topography and acquisition of spatial navigation in rats behaviour49
Human TRBP and PACT directly interact with each other and form a complex with Dicer to promote the production of small interfering RNA90
Heparan sulfate proteoglycans complexed neutrophil elastase differentially modulate inhibition by physiological anti-elastases (Observations in bronchial secretions of patients with bronchiectasis)92
Discovering gene function and disease mechanisms through forward and reverse developmental genetics84
Understanding the Function of Sedl gene and the Molecular Pathogenesis of spondyloepiphyseal Dysplasia Tarda111
Inhibition of E3 ubiquitin ligase WWP1 with SELEX generated DNA aptamers106
Dissecting the mechanism of binding between polyphosphate and polyphosphate kinase 2134
An essential role for type IIA procollagen in mouse inner ear development102
The role of Pax6 in beta-amyloid-induced neuronal apoptosis84
Molecular mechanism of disease for spondyloepiphyseal dysplasia tarda-effect of mutations on sedlin structure and function102
Chondrogenic differentiation of human mesenchymal stem cells in three-dimensional collagen/chondroitin-6-sulfate gels: Influences of cell seeding density and collagen concentration114
An insertional mutation causing altered coat colour & vestibular dysfunction in mice91
Development of 3D system for culturing notochordal cells91
Combinatorial use of chondroitin sulphate lyase subtypes in the treatment of nerve injury183
Role of yeast peroxiredoxin, Tsa1p, in DNA damage response103
Nucleic acid aptamers – tools for chemical biology105
Genetic association studies in lumbar disc degeneration: a systematic review47
Depleting Suv39h1 methyltransferase rescues defective DNA repair and extends lifespan in progeria mouse model29
Functional studies on sedlin108
Polyubiquitination of REV1 is regulated by REV7101
Manipulating the mouse genome to understand human disease99
Purification and charaterization of a physiological substrate of PKJ in central nervous system myelin91
Perineuronal chondroitin sulfates and semaphorin 3A regulate postnatal maturation of the vestibular circuit for gravity detection26
Viral and cellular regulators of Type I interferon production85
Mouse model with impaired matrix remodeling in endochondral ossification73
The role of Cell-matrix interactions mediated by β1 integrin in notochord development and function88
Reduction of cell proliferation in human colon cancer cell line by hexamethylene bisacetamide (HMBA)99
Understanding the function of the SEDL gene and the molecular pathogenesis of spondyloepiphyseal dysplasia tarda90
The role of procollagen IIA as a facilitator of BMP signaling in Heart development87
Activation of epidermal-growth factor receptor leads to growth inhibition and phosphorylation of the SHC-protein in a human nasopharyngeal cell line118
Kinesin-1 is necessary for cytokinesis in chondrocytes129
Chondroitinase ABC-I and -II linked chitosan microbeads increase neurtire length in CSPG-enriched astrocyte culture44
Polymer encapsulated human osteoblastic cells form ectopic bone in mice118
Protective effects of salvianolic acid B, astragaloside IV, and DT on endothelial cells against damage induced by H2O2125
The biological effect of fenretinide in nasopharyngeal carcinoma cells112
Age-related changes versus degenerative disc disease109
Chondroitin sulfate proteoglycans (CSPG) produced by schwann cells in astrocyte-schwann cell cocultures limit neurite extension and crossing of cellular boundaries88
Improvement in detection of missing heritability and genetic risk prediction in genome-wide association studies using 1000 genomes-based imputation49
Proteomics analysis of the human intervertebral disc reveals potential fibrotic events in degeneration39
New bone formation with osteoprogenitor cells confined in sodium alginate microcapsules218
Suppression of nickel release in nickeltitanium alloys by plasma immersion ion implantation surface treatment: towards a new generation of "smart" orthopaedic implants127
Constructing epigenetic regulatory networks from high throughput gene expression and ChIP-seq data40
Cloning, recombinant expression and digestion product characterization of chondroitinse ABC I and II107
Roles of mitochondrial trafficking proteins in type-I interferon production116
Immobilized chondroitinase ABC I and II on chitosan beads improve axonal regrowth in CSPG-enriched astrocyte culture31
Hypertrophic Chondrocytes Can Become Osteoblasts and Osteocytes in Endochondral Bone Formation92
The roles of perineuronal nets and heparanase in synaptic plasticity at the hippocampus114
Role of neuregulin 1 type III in the generation of fate committed Schwann cells from bone marrow stromal cells23
In vivo study of asporin, a genetic risk factor for intervertebral disc degeneration133
Abnormal enteric ganglia development in transgenic mice with ectopic expression of mutant Sox10 in the vagal neural crest.140
Perineuronal net regulates synaptic plasticity of central circuitry116
Ectopic expression of unfolded mutant collagen X in bone cells results in generalised hyperostosis in mice83
Impact of extracellular inorganic polyphosphate on osteoblast proliferation, differentiation and apoptosis96
The role of the AU-rich element in the mRNA of the stress-inducible protein CHOP/Gadd153105
Injury-associated changes in the disaccaride composition of chondroitin sulphates in post-crush sciatic nerves of adult guinea pigs101
PDSS2 requirements for cerebellar development and functions39
Chondroitin sulfate moieties that are upregulated in Schwann cell-astrocyte encounters104
Explant cultures of embryonic rat dorsal root ganglia exhibit heparanase expression in migrating cells114
Rabbit bone marrow derived mesenchymal stem cells induced collagen gel contraction-fabrication of tissue-like structures with different cell densities116
Assessment of aligner and SNP caller for next generation sequencing and a fast and accurate SNP detection method59
Intervertebral disc cryopreservation160
The genetics of the degenerative intervertebral disc disease114
Integrative analysis of high throughput data for regulatory network construction25
The role of Hox genes in otic vesicle patterning in Six1 regulatory pathway119
Lack of β1 integrin results in defective notochord morphogenesis with impaired convergent extension in the mouse94
Mouse model with impaired collagen X degradation at the chondro-osseous junction75
Formation of novel pattern by programming cell motility128
Regulation of synaptic plasticity by the partnership of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor38
Over-expression of mutant SOX10 in the vagal neural crest causes hypoganglionic colon development in transgenic mice111
Identification and characterization of distal regulatory element of human NGB gene131
Collagen-mesenchymal stem cell microspheres for the repair of articular cartilage defects in a rabbit model.54
In vivo study of asporin polymorphic variants in chondrogenesis and degenerative skeletal diseases122
Hoxb1 cooperates with Gli to mediate sonic hedgehog signaling in the neurogenesis of hindbrain100
KIF5b is essential for growth plate organization, cytokinesis and chondrocytes differentiation92
Intracellular Reactive Oxygen Species enhances the survival of cells under the conditions of ER stress80
Analysis of the Static Protein Profile of Degenerated IVD Indicate Increased Fibrosis-Related Proteins88
Differential regulation of retinoic acid signaling in adult spinal cord neural progenitors141
Chondrocytes from the endplate cartilage contribute to the inner annulus fibrosus in normal and degenerative intervertebral disc57
The role of reactive oxygen species in UPR-mediated cell death94
An essential role for Sox2 in inner ear development111
Differentiation and progression of interzone cells as progenitors of articular chondrocytes in joint formaiton55
Regeneration of the nucleus pulposus cells for Degenerative Disc Disorder31
The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution131
Inositol phosphates: the elucidation of forms and functions91
Abnormal IHH signaling affects distal digit patterning in a mouse model with brachydactyly type A1140
Insights into the function of SOX9 and campomelic dysplasia104
MT1-MMP inactivates ADAM9 to regulate FGF signaling26
Stem Cell decline and Aging40
EATdb: a database of human enhancers and their putative targets57
Linkage analysis on familial early-onset degenerative disc disease105
Nucleic acids aptamers for malaria diagnosis - discovery, structure and application47
Ubiquitination and proteosome dependent degradation of the activated form of human liver-enriched transcription factor CREB- H30
Visualizing the proteome of escherichia coli by recombineering technology115
Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vitro study with peripheral nerve conduits95
In silico mapping of a charcot-marie-tooth disease gene in a pedigree of Hong Kong Chinese99
Expression of heparanase in newborn mouse growth plates112
Postnatal maturation of the vestibular circuit for gravity detection is regulated by perineuronal semaphorin 3A and chondroitin sulfates34
Exploring the mutations at the C-terminus of human G6PD88
Nuclear and cell membrane surface area alteration in hexamethylene bisacetamide (HMBA) induced human colonic carcinoma cell line (LoVo)100
Three genes in the aggrecan degradation pathway act synergistically to predispose to degenerative disc disease169
Cardiac developmental defects in a Hoxb mouse mutant Hoxb3lacZ89
In vivo analysis of the transactivation specificity of group E SOX proteins90
Sox2 as a master regulator of prosensory development in the mouse inner ear35
Defining the role of Sox9 in early development by tissue specific gene inactivation116
In vitro and In vivo biocompatibility od dual carbon and nitrogen plasma modified titanium alloy39
Duplication and divergence of SoxE function during chordate evolution34
Gain-of-function Hoxb3 mutation affects endothelin-1 pathway in craniofacial development128
Vancouver prevalence of intervertebral disc degeneration: a MRI study of 769 volunteers132
Regeneration of nucleus pulposus cells for Degenerative Disc Disorder36
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda107
New approaches to osteoporosis therapy with aptamer-based inhibitors109
Isolation and detection of type IX collagen from adult human intervertebral disc94
Early results of the effect of lack of collagen X on fracture healing90
Identifying transcriptional regulatory elements directing hypertrophic chondrocyte-specific expression of Col10a1107
Allogeneic mesenchymal stem cell transplantation into the intervertebral disc; effect of severity of degeneration and cell number on regeneration118
Association and functional analysis of ADAMTSS in lumbar disc degeneration86
Refining orthologue groups at the transcript level175
Towards myelin repair in the CNS: oligodendrocyte precursors derived from bone marrow stromal cells258
Resveratrol rescues Sirt1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria73
Understanding molecular mechanisms in mitochondria underlying LRRK2-related Parkinson’s disease151
DNA origami integrated to aptamer-mediated molecular recognition58
Functional study of cerberus-like protein: towards a biochemical understanding of BMP antagonists in skeletal disorders109
Cadherin 2/N-cadherin regulates notochordal cell function and intervertebral disc homeostasis56
HOXB3 Mutation Generated By Gene Targeting Leads to Plasmacytoma105
Regulatory role of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor in synaptic plasticity90
Loops, hairpins and flipped bases: a DNA aptamer that discriminates Plasmodium lactate dehydrogenase from the blind watchmaker75
Kif5b is responsible for muscle development and normal function111
Changes in perineuronal nets within the rat vestibular nuclei during development and after unilateral labyrinthectomy110
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation42
Reconstitution Of Nucleus Pulposus Cell Matrix Niche In 3D Collagen Microsphere For MSC Discogenic Differentiation62
Foxa2 minimal notochord enhancer element mediates Cre expression in the node and notochord131
The role of Sox2 and Sox18 in mouse hair development28
Aligned chitosan nanofibers seeded with Schwann cells for construction of a nerve guidance channel93
The impact of Hoxb3 mutation on plasmacytoma117
Developing three dimensional culture system for Notochordal cells65
Generation of induced pluripotent stem (iPS) cells from bone forming cells33
Reactive oxygen species (ROS) regulates the expression of the growth-arrest and DNA damage inducible gene-153 at the post-transcriptional level95
The antiproliferative effect of the kappa-specific opioid receptor agonist U50,488H does not correlate with the suppression of cyclic AMP and mobilisation of intracellular calcium126
Tumor Suppressive Functions of Krüppel-like Factor 4 (KLF4) in Neuroblastoma116
Epidermal-growth factor is not a mitogen for the nasopharyngeal carcinoma-derived cell line, CNE-2103
CRTC1 transcriptional coactivator is required for hepatitis B virus gene expression and replication54
The Role of Cyclooxygenase 1 and 2 in Bone Repair90
The role of Suppressed of Fused in neural stem cell proliferation29
GWASdb: a database for human genetic variants identified by genome-wide association studies45
The role of PERK pathway in adaptation of hypertrophic chondrocytes to ER stress52
MT1-MMP regulates FGFR signalling in development77
Roles of liver-enriched transcription factor CREB-H in hepatocellular carcinoma115
Targeting Notch Signalling to Generate Bone Marrow-derived Schwann Cells for Transplantation in Spinal Cord Injury53
ProteoMirExpress: inferring microRNA activities from mRNA and protein expression data96
Expression of mutated HPN - a nickel binding protein from helicobacter pylori134
Chondroitinase treatment enhances axonal regrowth through schwann cell-seeded channels after spinal cord hemisection in adult rats139
Immunogold localization of alkaline phosphatase in a human osteosarcoma cell line (SAOS-2)82
Long term expression of small interfering RNA targeting M2 gene induces effective inhibition of influenza A virus replication106
An insertional mutation affecting coat colour and vestibular function in mice84
Kinesin-1 is necessary for cytokinesis in chondrocytes32
Role of matrix remodeling in endochondral bone formation96
A3.5 Molecular pathogenesis of SEDT: the role of sedlin and its cytoplasmic function111
Role of IHH signaling in the progression of joint formation in digit development85
Purification and identification of sclerostin interacting partners: steps towards therapy with aptamer-based inhibitors95
Age dependent association of the COL9A2 Trp2 allele with intervertebral disc degeneration, annular tears and end-plate herniations120
Timeless interacts with Parp1 to promote homologous recombination repair84
A novel PS1 case of variant Alzheimer’s Disease with Spastic Paraplegia: the search for a gene-modifier105
Role of IHH signaling in the progression of joint formation in digit development82
The transcription factor WIN alters cell cycle kinetics through modulation of cyclin expression89
Spatiotemporal relationship between chondroitin sulfates and chondroitin 6-sulfotransferase in the neuroepithelium during mouse hindbrain development86
BDNF regulates plasticity in spatial coding158
Strengthening biomedical science education among non-medical students through a common core course130
Investigating the protective role of FOXM1 against oxidative stress and DNA damage in human embryonic stem cells104
DNA aptamers as inhibitors of E3 ubiquitin ligase WWP1134
Sox10 NGFP mutation affects migration of enteric neural cress cells in mouse embryonic gut102
Glycosaminoglycan composition in the regenerative environment of the sciatic nerve of adult hamsters87
Effects of glycoproteins and glycosaminoglycans on the crystallization of urinary calcium oxalate103
Study of nickel suppression and cyto-compatibility of plasma immersion ion implantation treated nickel titanium shape memory alloys119
HS/syndecan modulate proteolytic balance in airway inflammation106
Understanding the molecular pathogenesis of SOX9 Y440X campomelic dysplasia89
Sox10 mediates proliferation and migration behavior of enteric neural crest cells107
Exploring functional variation affecting miRNA and ceRNA regulation in humans79
Fate of Mesenchymal Stem Cells Injected Into Intervertebral Discs95
Polymorphisms of the ACE2 and CD13 (ANPEP) genes, and susceptibility to SARS coronavirus infection in Chinese from Hong Kong319
DNA aptamers for diagnostic applications – structural insight into discriminatory recognition of malaria diagnostic targets28
Spdzd2 is a putative regulatory factor of insulin gene expression and pancreatic b-cell growth117
Fate Commitment in Bone Marrow Stromal Cell Derived Schwann Cells is Dependant on Axonal Contact104
The effect of severity of disc degeration on mesenchymal stem cell's ability to regenerate the intervertebral disc101
The role of SOX10 in enteric neural crest cell migration39
Injury-associated increase in 6-sulphated chondroitin sulphates in post-crush sciatic nerves of adult guinea pigs94
Regulatory role of Sox9 in chondrocyte hypertrophy105
The role of HPN and its related histidine-rich proteins in helicobacter pylori120
Model Systems for Intervertebral Disc regeneration101
Mouse Model of Familial Parkinson’s Disease based on Variant Leucine Rich Repeat Kinase 2 (LRRK2)127
Immunostimulatory function of measles virus defective interfering RNA35
Serglycin in neutrophils: retention of neutrophil elastase in granules and inhibition of neutrophil elastase activity during storage84
Abnormal development in transgenic mice expressing a campomelic dysplsia Sox9 mutation106
Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant96
Linkage analysis on familial early onset degenerative disc disease126
Solution structures and dynamics of the sterile α Motif (SAM) domain of the deleted in liver cancer 2 (DLC2): a monomeric structure with membrane-binding properties126
Comprehensive Analysis of MRI‐phenotypes Provides New Insights into Lumbar Disc Degeneration for Genetic Studies85
Sox2 is Required for Sensory Organ Development in the Inner Ear102
Transcriptome of the human intervertebral disc in health and disease110
The role/s of type IIA procollagen in BMP (Bone morphogenetic protein) Signalling100
Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome: a report of 3 new Chinese patients in Hong Kong106
Single nucleotide polymorphisms of complement component 5 and periodontitis114
A proteomic approach to study the molecular mechanisms of the unfolded protein response in the endoplasmic reticulum of chondrocytes99
KIF5B contributes to cell polarization during epithelial morphogenesis31
DNA-encoded dynamic libraries64
Urinary glycosaminoglycans differ in their calcium oxalate crystallization activities102
Aptamer-based piezoelectric quartz crystal biosensor for SARS coronavirus helicase42
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations51
The role of extracellular matrix in planarian regeneration26
Cell-intrinsic switch to the fate commitment of bone marrow-derived Schwann cells112
STK11 inhibits transcriptional activation of HTLV-I LTR by tax transactivator26
Purification and targeting sclerostin: steps towards, osteoporosis therapy111
Immobilization of chondroitinase ABCI on chitosan beads to improve axonal regrowth in CSPG-enriched astrocyte culture91
Sox2 is required for sensory organ development in the inner ear85
The regulatory role of perineuronal nets and semaphorin 3A in the developmental maturation of the central vestibular circuitry28
Nucleic acid aptamers against Plasmodium lactate dehydrogenase for malaria diagnosis - discovery, characterization, structure and application57
Functional significance of the 3’-UTR in the mRNA of the stress-inducible protein CHOP/Gadd15385
The phenotype study of PDSS2 conditional knockout mouse117
Studies of kappa opioid receptor in mediating stress response via the phospholipid C pathway80
Essential and dose-dependent requirement for the sedlin component of the trapp complex in development118
Chasing Ehrlich’s Magic Bullet – Nucleic acid aptamers for therapy and diagnostics24
In vivo study of asporin polymorphic variants in chondrogenesis and degenerative skeletal diseases80
Descendents of LGR5-expressing interzone cells are localized to the superficial layer of the articular cartilage63
Novel plasma-implanted shape memory alloys in orthopaedics88
Dissecting the transition from hypertrophic chondrocyte to osteoblast in skeletal development and growth56
b-Chemokine Polymorphisms are not Associated with Tuberculosis in the Hong Kong Chinese Population108
Perturbation of GABAergic transmission during a postnatal critical period alters behavior in path integration task25
Heparan sulfates that upregulate regeneration of psot-traumatic sciatic nerves of adult guinea pigs102
Protein expression of the intervertebral disc: in Health and disease86
Characterize the specificity of CRE expression in cerebellar purkinje cells84
Hexamethylene bisacetamide changes proteoglycan metabolism in a human colon cancer cell line81
Understanding the contribution of Lgr5+ interzone progenitor cells in articular cartilage regeneration56
Molecular and developmental insights into the pathogenesis of the SOX9Y440X campomelic dysplasia mutation144
Involvement of PDZD2 in Regulating Pancreatic Beta Cell127
Extracellular matrix and the stem cell niche in the regenerating planarian96
Heparanase colocalizes with syndecan-3 in neurons of normal adult spinal cord107
Adeno-associated virus vector-mediated angiogenic inhibitors suppress lung tumor growth in mice101
Involvement of neuregulin 1 type III in the EX Vivo generation of fate committed schwann cells from bone marrow stromal cells36
Effects of oligosaccharide products on activity of chondroitin sulphate ABC lyase I – Towards improving the efficacy of the enzyme for in vivo treatment103
The functional crosstalk between MT1-MMP and ADAMs30
Hoxb1 cooperates with Gli to activate Nkx2.2 expression in the neurogenesis of mammalian hindbrain rhombomere 488
Hypertrophic chondrocytes become osteoblasts and osteocytes contributing to endochondral bone formation61
Abnormal chondrocyte differentiation in transgenic mice expression a Schmid metaphyseal chondrodysplasia Col10al mutation147
Characterization of candidate tumor suppressor gene, DLC-1 in hepatocellular carcinoma135
An essential role for type IIA procollagen in heart development98
A Novel Neural Response Algorithm for Protein Function Prediction43
Kinesin-1 affects chondrocytes adhesion to extracellular matrix and motility37
Laminopathy-based premature Aging68
Identification of master regulators in non-small-cell lung carcinoma19
MT1-MMP in regulating growth factor signalling and development35
Strontium combined with calcium increases vertebral bone mineral density and stiffness in goats121
DNA aptamers that inhibit aggrecanase activity for degenerative disc disease and osteoarthritis therapy29
Dissecting the mechanism of how mycobacterium tuberculosis polyphosphate kinase 2 binds to polyphosphate43
A preliminary study for development of oral vaccines for poultry and wild birds against avian H5N1 influenza virus infection82
Effect of MAD2 expression on chemosensitivity to DNA damaging agent cisplatin in nasopharyngeal carcinoma cells128
In vivo study of asporin, a genetic risk factor for osteoarthritis and degenerative disc disease89
Use of sulfated maltoheptaose to lower neutrophilic inflammation in a rat model of cigarette smoke-induced chronic obstructive pulmonary disease112
MIT-MMP in FGF signaling103
Engineering Bacterial Chromosomes: E. coli and Beyond120
Herpes simplex virus type 1 Us11 protein inhibits type I interferon production by suppressing PACT mediated activation of RIG-I52
Academy of Mathematics and Systems Science62
Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat86
Genetic variation in the COL9A2 gene and its association to intervertebral disc abnormalities in Southern Chinese155
Stimulation of in vitro mineralization on strontium-containing hydroxyapatite bioactive bone cement115
Sputum sol in bronchiectasis stimulates IL-6 production from bronchial epithelial cells103
The double-stranded RNA-binding protein PACT is a cellular activator of MDA5 in innate antiviral immune response95
Differential stability and transcriptional activity of CREB3 subfamily transcription factors101
The leukaemia fusion gene, Mll-Een affects haemopoietic development in mouse embryonic stem cells with enhanced proliferation and self renewal of myeloid progenitors112
Sulfated maltoheptaose is a potential therapeutic in reducing neutrophilic inflammation in a cigarette smoke-induced rat model of chronic obstructive pulmonary disease86
Developing a new approach to degenerative disc disease therapy: DNA aptamers to inhibit aggrecanases140
The role of SoxE transcription factors in melanoma development105
Derivation of stable Schwann cells from human bone marrow stromal cells43
Abnormal enteric nervous system development in a Sox10-EGFP mutant mouse162
iCartiGD: the Integrated Cartilage Gene Database124
Histological and mechanical property abnormalities of bone fracture healing in the absence of collagen type X136
Notch Signaling in in vitro derivation of Schwann cells from bone marrow stromal cells59
Construction of new DNA vectors based on promoters of Epstein-Barr virus-encoded small RNAs for expression of small hairpin RNAs in mammalian cells105
An integrated metalloproteomic analysis depicts the proteomic features of helicobacter pylori in response to Bi(III)72
Expression of chondroitin sulfotransferases in the injured spinal cord148
Maturation profile of thalamic neurons responsive to rotational and translational motions107
Expression and electrophysiological studies of secretin in the rat hypothalamic paraventricular nucleus135
EpiRegNet: constructing epigenetic regulatory networks from high throughput gene expression data for humans128
Activation of translocation of CDC2 in dexamethasone-induced apoptotic human nasopharyngeal carcinoma CNE3 cells94
Endocannabinoid modulates developmental plasticity of central vestibular synapses andthe expression of vestibular behaviors in rats69
Heparanase modulates synaptic plasticity at the hippocampus121
Developmental lumbar spinal stenosis in Southern Chinese: findings from a genome-wide association study42
Control of cranial motor neuron migration by divergent expression of chondroitin sulfotransferases in rat hindbrain development26
Differential involvement of perineuronal net components in functional modifications of rat vesticular nucelar neurons89
Reactive oxygen species (ROS) regulates the expression of the growth-arrest-and DNA-damage inducible gene at the post-transcriptional level93
Is there a role for Hedgehog genes in Hirschsprung's diseases?109
Resveratrol rescues adult stem cell decline and ameliorates progeroid features in Zmpste24 deficient mice26
Development of novel viral promoter-driven DNA vectors for expression of siRNAs to mediate RNA interference in mammalian cells90
Genetic analysis of the role of procollagen IIA as an extracellular regulator of BMP signaling107
Fate commitment of human bone marrow stromal cells to Schwann cells36
Towards myelin repair in the CNS: generation of oligodendrocyte precursor ce lls from adult bone marrow stromal cells32
Functional characterization of a novel RhoGAP protein Deleted in Liver Cancer 2 (DLC2)96
GABAergic transmission in the critical period impacts on the thalamic spatial map and navigation behavior49
Integrating genetic linkage analysis and computational prioritzation in identifying host genetic factors response to influenza A virus infection50
Interactions of bismuth with proteins and enzymes: insight into its mechanism of action116
Uncovering small chemical molecules for treatment of intervertebral disc degeneration78
Dosage-dependent requirement of Sedlin and Sedlin-like proteins in mouse yolk-sac visceral endoderm and embryo development42
An integrated approach for identification of metallodrug binding proteins in cells44
Investigating the role of Sox9 in human neural stem cells52
Induction of osteo-chondroprogenitor formation by defined transcription factor-mediated reprogramming process38
Activity assays of Chondroitinase ABCI immobilized on chitosan beads160
Psr1p interacts with SUN/sad1p and EB1/mal3p to establish the bipolar spindle39
Loss of MKP3 is associated with cisplatin-resistance and tumorigenicity of ovarian cancer90
Integration of factors and pathways facilitating chondrocyte adaptation to ER stress28
In vivo functional analysis of SOX9 by conditional expression of a mutant SOX9, SOx9Y440X90
Developing vestibular commissural projections display differential patterns with chondroitinase treatment of the hindbrain83
Study of enhanced corrosion resistance and biocompatibility by plasma implantation of nickel-titanium alloys: an in-vitro and surface chemcial analysis104
Inhibition of the SARS coronavirus by Bismuth compounds111
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H84
A mouse model for hearing and balance defects in campomelic dysplasia113
The role of Sox2 in mouse hair morphogenesis93
Use of mesenchymal stem cells for intervertebral disc regeneration: A rabbit model91
Involvement of PDZD2 in The Regulation of Pancreatic Beta Cell Development and Function107
New plasma surface treated memory alloys: Towards a new generation of "smart" orthopaedic materials129
Functional study of stem-cell-derived Schwann cells using an in-vitro dorsal root ganglia model111
Collagen X deficiency exacerbates pathological calcification and impairs carilage remodeling in MGP-null mice51
Inhibition of prostate cancer cell growth by human sPDZD2 protein113
Assessment of systemic inflammation in osteoarthritis patients by testing fatty-acid-binding protein 4 and adiponectin in plasma60
The effect of severity of degeneration on intervertebral disc regeneration by use of mesenchymal stem cells103
Mapping the locus for a novel cataract mouse mutant with microphthalmia and closed eyelid104
The roles of Irx3 and Irx5 in mammalian inner ear development50
Prediction of osteoporosis candidate genes by computational disease gene identification strategy112
Purification and characterization of the ganglioside-stimulated protein kinase in mammalian brain111
Comparison of fatty-acid-binding protein 4 and adiponectin levels in infrapatellar fat pad and subcutaneous adipose tissue, synovial fluid and plasma in subjects with knee osteoarthritis82
The role of autophagy in ER-stress induced chondrocyte re-differentiation91
Tenogenic differentiation of human mesenchymal stem cells on novel bio-imprinted scaffolds51
Cell Repopulation of the Frozen Intervertebral Disc by Bone Marrow-derived Stromal Cells101
The effects of cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair81
Overexpression of the winged helix transcription factor WIN in HeLa cells alters cell-cycle kinetics86
Small-molecule suppressors of proteoglycan catabolism in degenerative disc cells37
Association of ABCA1 gene with Sporadic Alzheimer's Disease in Chinese Group and potential functional importance for Novel Intronic Polymorphism123
A Novel Non-invasive Role of Heparanase: Promotion of Cartilage Matrix Mineralization83
Chondroitinase ABC-I and -II linked chitosan microbeads improve axonal regrowth in CSPG-upregulated astrocyte culture44
Probing the mechanistic basis of the bacteriophage lambda-encoded recombination system in E. Coli107
Modifications in perineuronal nets of rat vestibular nuclear neurons after unilateral labyrinthectomy96
Hox Expression Profile and its Epigenetic Regulation during Chondrogenesis102
Impact Of Activating Adamts-5 In Cartilage-related Degenerative Disorders91
Lack of β1 integrin in the developing mouse notochord results in hemivertebrae109
MIP-T3 is a novel inhibitor in TBK1/IRF3-dependent antiviral response119
Mechanical force controlled epithelial morphogenesis27
Increased release of heparan sulfate proteoglycans from a human colon cancer cell line treated with hexamethylene bisacetamide84
Regulation of spatially-specific expression of the mouse homeobox gene Hox b-3106
Shape transformation of the nuclear envelope during closed mitosis74
In Vivo Analysis of Specificity of Target Gene Transactivation by SOX993
Genome-wide association study of adolescent idiopathic scoliosis in southern Chinese106
Genome-wide association study of adolescent idiopathic scoliosis in southern China110
ER-stress induces early onset intervertebral disc degeneration in a mouse model for metaphyseal chondrodysplasia type Schmid105
Functional roles of type IIA procollagen89
PDZD2, a candidate gene for brachdactyly type A1, encodes a secreted protein that negatively modulates hedgehog signalling37
Protein Expression Profiles of the Intervertebral Disc117
A γA-crystallin mouse mutant Secc with small eye, cataract and closed eyelid146
Neutrophil elastase binds serglycin during storage in granules and changes its binding partner to shed syndecan-1 after degranulation100
Expression of chondroitin 6-sulfate in neuroepitheilial boundaries in mouse embryos106
C6ST expression in sciatic nerve explant culture of adult rats104
Investigating the protective role of FOXM1 against oxidative stress and DNA damage in human embryonic stem cells37
Sox2 is required for sensory organ development in the inner ear112
Significance of ligamentum flavum hypertrophy in developmental spinal stenosis33
The role of Sox2 and Sox18 in mouse hair development85
Disruption of the mouse Hoxb3 locus affects ventral body wall development79
Prelamin A compromises DNA Damage-induced Chromatin Relaxation to Promote Genomic Instability and Aging100
Characterization of a novel MAD1 isoform, MAD1β, in hepatocellular carcinoma92
Role of heparanase in synaptic plasticity at the hippocampus and vestibular nucleus116
Controlling mitochondria distribution with chimeric proteins27
Preparation of chitosan fibers for nerve regeneration37
Cyst formation: mathematical model and data analysis29
Reactive oxygen species stimulate phosphorylation of eIF2α independent of protein folding in ER-stressed cells87
Protein and gene expression profiles of the intervertebral disc: in health and disease101
The role of HOX genes in mouse inner ear development.86
Differential regulation of FOXM1 isoforms by RAF/MEK/ERK signaling62
Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes50
Cyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal cord80
Chondroitin sulfate proteoglycans (CSPG) and hyaluronan at borders between astrocytes and schwann cells restrict neurite crossing78
Ganglioside-stimulated protein kinase in brain: effects of trisialoganglioside GT1b/detergent mixed micelles on intrinsic enzymic activity96
Investigating the role of SOX9 in human neural stem cells32
ASCL1 is essential in maintaining CD133+ cancer stem cells in HCC69
The restrictive role of chondroitin sulfate moieties on the migration of cranial motor neurons in rat hindbrain development85
A proposed model for UPR-mediated cellular survival and cell death102
Nano-scale morphology of disc collagens and their correlation with disc mechanics141
Mechanisms Underlying Chondrocyte Reprogramming Surviving ER Stress85
The CRISPR/Cas9-mediated genome editing of Epstein-Barr virus: a new platform for genetic study26
Heparanase modulates synaptic plasticity at the hippocampus100
Genetic Study in AD, The Way Forward21
Quantitative characterization of mesenchymal cell aggregation process25
Association studies of intervertebral disc disease with genes in the aggrecan degradation pathway105
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans40
Instructive role of DRG neurons in derivation of schwann cells from bone marrow stromal cells57
Prevalence of intervertebral disc degeneration: a MRI study of 769 volunteers115
In vivo chondrocytic differentiation of the allogenic stem cells in the murine intervertebral disc144
Using small molecules to induce the progressive differentiation of hESCs into pancreatic β-cell-like progenitors49
Localization of murine embryonic stem cells at the area of myocardial infarction in mice heart87
Sedlin and prostaglandin E2 dehydrogenase - interactions and implications for spondyloepiphyseal dysplasia tarda94
Functional analysis of SM22β by targeted gene deletion in mice90
Derivation of oligodendrocyte precursors from bone marrow stromal cells for remyelination therapy149
iPS Reprogramming in Premature Aging Mouse Model - Zmpste24 Deficient Mice90
Fate and properties of notochordal descendent cells in the intervertebral disc: implicationto disc degeneration144
Single-stranded oligonucleotide-medicated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair113
A comprehensive database for GWAS¬identified human genetic variants: an update of GWASdb144
The role of genetics in pain122
Genetic polymorphisms and periodontitis in Hong Kong Chinese100
Characterization of molecular and cellular consequences in OI type V osteoblasts38
Nano Structure and Biomechanics of Human Intervertebral Disc Collagens108
The immunologic and metabolic features of Chinese patients with a typical diabetes mellitus105
Conditional Ptc1 knockout in vagal neural crest cells causes a reduced proliferation of enteric nervous system progenitors and intestinal hypoganglionosis162
Inhibition of antiviral innate immunity by influenza virus NS1 protein107
The autocrine sPDZD2 protein is a potential p53 activator110
KIF5b interaction with NMDA receptor mediates NO production in neuron86
PACT targeting is a novel viral strategy of innate immune evasion41
Exchange protein directly activated by cAMP 1 is involved in β3-adrenergic induction of brown adipose tissue in white adipose tissue40
Genetic analyses of terminal differentiation of hypertrophic chondrocytes126
Functional significance of the 3'-UTR in the mRNA of the stress- inducible protein CHOP/Gadd15319
p53 represses the transcription of mitotic checkpoint gene MAD1104
Free-flow electrophoretic separation of isolated matrix vesicles of rabbit epiphyseal growthplate cartilage101
An IFN-a/b receptor 1 promoter variant and hepatitis B virus synergistically increase the susceptibility to chronic hepatitis B99
Genetic basis of skeletal dysplasia, ear development & congenital deafness – lessons from mose models of human malformations42
Correlating protein structure with disease - understanding the mechanism of SEDT162
Investigation of the homing ability of mesenchymal-like stem cells to sites of injury using a mouse model of IVD degeneration113
Investigating the role of FoxM1 in the maintenance of human embryonic stem cell pluripotency31
Functional Genomics: Lessons learnt from manipulating the mouse genome75
Endocannabinoid regulates developmental plasticity of GABAergic synapses in the rat medial vestibular nucleus47
Kinesin-1 is involved in chondrocytes adhesion to extracellular matrix and motility43
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions34
Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p144
Inositol lipids in cardiomyocytes: relationship to k-agonist signal transduction126
Evidence for a new gene associated with Hirschsprung's disease: the PHOX2B gene106
Three-dimensional culture of bovine nucleus pulposus cells in protein matrices58
Differential Regulation of FoxM1 Isoforms by Raf/MEK/ERK Signaling88
Protein and gene expression profiles of the intervertebral disc: in health and disease102
Divergent routes for derivation of alternative glial cell fate from adult bone marrow stromal cells for remyelination therapy25
A characterization of the in vitro effects of metal ions on thioredoxin reductase188
Effect of impaired matrix turnover on differentiation of intervertebral disc cells27
Linkage analysis on familial early-onset degenerative disc disease(DDD)133
Hearing and balance defects in a mouse model of campomelic dysplasia94
Modulation of synaptic plasticity by the partnership of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor113
Over-expression of FoxM1 facilitates progression through G2/M phase and stimulates expression of cyclin B190
Building creative and collaborative assessment strategies into a large introductory biomedical sciences class - evidence for sustained deep learning and potential adaptability for MOOCs33
Strategy to study urinary glycosaminoglycans by high performance liquid chromatography103
Decellularization of chondrocyte-encapsulated collagen microspheres: a 3D model to study effects of acellular matrix on stem cell fate105
A versatile microscopy to study biological pattern formation177
Interplays between RNA-binding proteins determine viral infection outcome41
Genetic analysis of alzheimer's disease associated genes: a perspective from abnormal cholesterol metabolism105
Sox10 mutation affects gliogenesis of the cochleo-vestibular ganglion130
Cloning, expression, purification and characterisation of escherichia coli polyphosphate binding domain as a new tool to understanding polyphosphate synthesis and function38
Subversion of innate antiviral immune response by Middle East respiratory syndrome coronavirus31
Overexpression of Hoxb3 affects inner ear neurogenesis85
Insights into the function of Sox9 and the molecular pathogenesis of campomelic dysplasia84
Identification of 'Stemness' genes by integrating differentially expressed genes from multiple stem cell microarray databsets106
Immunohistochemical localization of chondroitin sulfate proteoglycans in the developing rat hindbrain138
Dissection of biophysical properties and biological activities of Bet/RecT family DNA recombination proteins43
The effect of pollutant-induced cellular stress on mRNA stability19
GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications78
Global gene expression changes during chondrocyte adaptation to ER stress128
Bioinformatics studies of gene regulation of SOX9 and the SOX family88
Time-lapse imaging of planarian regeneration46
Aptamers against P. falciparum histidine rich protein 2 as a new approach to malaria diagnosis78
Modifications in perineuronal nets of rat vestibular nuclear neurons during postnatal development and in injury109
Histidine-rich protein, HPN and metallothionein: are they similar?98
Hypertrophic chondrocytes under ER stress utilizes the hypoxia stress pathway for survival41
Presence of notochord descendent cells in the nucleus pulposus of adult mice showing signs of intervertebral disc degeneration114
New approaches for therapeutic aptamer selection and delivery101
Piezoelectric quartz crystal biosensor for SARS coronavirus helicase based on aptamer104
Human T-cell leukemia virus type 1 oncoprotein Tax preferentially interacts with a group of cellular coiled-coil proteins108
Investigating the role of FOXM1 in the maintenance of human embryonic stem cell pluripotency108
Use of chondroitin sulphate lyase subtypes to overcome molecular barriers of reactive glia: implication for nerve regeneration112
Derivation of oligodendrocyte precursors from bone marrow stromal cells: new perspective in CNS myelin repair103
Analysis of craniofacial defects caused by ectopic expression of Hoxb3.105
Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2246
sPDZD2, a novel modulator in Hedgehog signaling84
The roles of Irx3 and Irx5 genes in mammalian inner ear development138
Association between CLU Polymorphisms and clinical phenotypes in Alzheimer’s Disease106
Delayed endochondral ossification and digit joint formation in mice expressing a brachydactyly type A1 mutation in Indian Hedgehog125
Activating ER-stress in differentiating osteocytes impairs maturation causing hyperostosis in mice107
Renal proteoglycans: roles in the initiation of renal stone117
Further study on the mechanism responsible for inhibition of cAMP production in CNE-2 and H9c2 cells upon k-opioid receptor stimulation80
In vivo analysis of the functional specificity of the transcription factor, SOX9, in regulation COL2A1/Col2a1104
Serglycin in the HL-60 degranulation product retains its sulfated chondroitin/dermatan moieties and affinity for neutrophil elastase114
Roles of yeast peroxiredoxins in cellular defense against DNA damage77
Serum metabolomic biomarkers and lumbar disc degeneration27
Disc cell responses to the local environment of degenerated and non-degenerated intervertebral disc tissue29
Involvement of neuregulin 1 type III in the Ex Vivo generation of fate committed schwann cells from bone marrow stromal cells136
Intervertebral disc regeneration by use of autologous mesenchymal stem cells, an experimental model in rabbits106
ChIP-array: gene regulation network construction from ChIP-seq/chip and mRNA expression data160
Inorganic polyphosphate and its impact on osteoblast function, signaling and gene expression86
Towards the understanding of nickel trafficking in helicobacter pylori: expression and brief characterization of a his-rich protein109
A mouse femoral external fixation model for the study of fracture repair81
ER-stress signaling in the pathogenesis of Schmid metaphyseal chondrodysplasia99
Regeneration of nucleus pulposus cells for degenerative disc disorder86
Sox10 mutation affects cochleo-vestibular ganglion gliogenesis103
Apolipoprotein(a) polymorphism in Hong Kong Chinese: genetic and hormonal effects103
Inhibiting sclerostin with a nucleic acid aptamer as a new approach to osteoporosis therapy115
A centrosomal target of human T-cell leukemia virus type I oncoprotein Tax117
The Regulation of FGF Signaling by MT1-MMP in Calvarial Osteogenesis42
Genome-wide association study of Degenerative Disc Disease (DDD)145
Comparison of the effect of non-selective NSAID and Cycloosygenoase-2 (COX-2) selective NSAID on bone formation - implications for spinal fusion100
Periostin interacts with sclerostin and inhibits its antagonistic effect on Wnt signalling167
Single nucleotide polymorphisms of Fc-gamma receptor genes and periodontitis115
Regulation of CREB3L2 and FUS-CREB3L2 Transcriptional Activity Through Proteasome-dependent Degradation83
Procollagen IIA facilitates BMP signaling in heart development90
Endocannabinoid regulates long-term synaptic plasticity contributing to the acquisition of vestibular behavior during postnatal development34
MT1-MMP regulates FGF signaling in osteogenesis121
Novel post transcriptional modification of UHRF1 and its biological relevance27
Chondroitin sulfate proteoglycans in astrocyte-Schwann cell cocultures limit neurite extension and crossing of cellular boundaries168
Role of cadherin 2 in intervertebral disc homeostasis37
Adenoviral delivery of RNA decoys restores cellular proapoptotic protein PUMA expression by silencing Epstein-Barr virus-encoded miR-BART5 in nasopharyngeal carcinoma cells34
Involvement of PDZD2 in regulating pancreatic beta cell function102
Herpes simplex virus type 1 Us11 suppresses innate antiviral immune response by preventing PACT-induced activation of RIG-I45
Towards an understanding of global gene expression changes in hypertrophic chondrocytes undergoing ER stress114
SPS: a simulation tool for calculating power of set-based genetic association tests67
New approaches for therapeutic aptamer selection and delivery94
Attempts to locate the expression of chondroitin sulfate during embryonic hindbrain development in mouse105
Aberrant KLF4 expression and BMP signaling cause proliferation defect in PTC1-/- neural crest cells139
Wholemount in situ hybridizationa nd transgenic analysis of the mouse Hoxb-3 gene106
Rewriting concepts on the ontogeny of bone cells20
Role of p53/p63 in chondrocyte re-differentiation upon activation of ER stress100
Hypoxia Inducible Factor-1-alpha in Healthy and Diseased Periodontium107
Genome-wide haplotype association mapping (HAM) in mice leads to an identification of a genetic variant in CER1 associated with bone mineral density and fracture in southern Chinese women115
Abnormal regulation of cartilage and bone growth in transgenic mice expressing a collagen X SMCD mutation114
To understand the expression profile and function of heparanase in the adult spinal cord83
Stable derivation of Schwann cells from human bone marrow stromal cells39
Identification and characterization of long-range SOX9 enhancers in limb development38
Ectopic expression of Hoxb3 in the hindbrain causes abnormal ear development105
Viral modulation of cellular signaling through SARS coronavirus structural proteins91
The proteomics of protein misfolding in chondrocytes93
Association between complement receptor1 polymorphisms and alzheimer's disease in southern Chinese population101
PACT, a double-stranded RNA binding protein, as cellular activator of cytoplasmic viral sensor MDA5133
Dual specific antibody co-targeting HIV-1 gp120 and gp41 inhibits virus entry by blocking the shedding of gp12089
Unfolded Protein Response Leading to Cataratogenesis in a Microphthalmia Cataract Mouse Mutant104
Perturbation of the plasticity at GABAeric synapses in the vestibular nucleus during a critical period impacts on the thalamic spatial network and navigation behavior54
The role of Indian Hedgehog in chondrocyte hypertrophy93
Regulation of SIRT6 activities by the lamins29
Bioinformatics study of the lineage and tissue specificity of gene expression127
Increased basal insulin secretion in Pdzd2-deficient mice35
Sox10 is required for proliferation and migration of enteric neural crest stem cells113
Creation of biological patterns controlled by synthetic genetic circuits56
Perturbation of GABA synapses in vestibular nucleus during a postnatal critical period impacts on the establishment of spatial recognition54
ChIP-Array: Gene Regulation Network Construction from ChIP-seq/chip and mRNA expression data40
Targeting heparan sulfate/syndecan-1 in attempts to restore the balance between neutrophil elastase and anti-elastase in bronchiectasis136
The potential of umbilical cord derived mesenchymal stem cells in intervertebral disc repair43
Purification and identification of sclerostin interacting partners: steps towards Osteoporosis Therapy with aptamer-based inhibitors119
Role of Conserved Domains in the Transcriptional Function of Sox 10 In Vitro and In Ovo91
Characterization of newly synthesized proteoglycans isolated form renal proximal tubular epithelial cells in culture84
Derivation of oligodendrocyte precursors from bone marrow stromal cells for mylination therapy49
In vivo selection and characterization of DNA aptamers against H5N1 virus nucleoprotein105
Peroxiredoxin-null yeast cells are genomically unstable119
An Ideal Mouse Model for Ageing Research115
Characterization of heparan sulphate proteoglycan recovered from cultures pf human bronchial epithelial cells105
Transgenic mice expressing human epidermal growth factor show stunted growth96
Suppression of HTLV-1 transcription by SIRT1 deacetylase113
Dual origin of osteoblasts in bone formation: terminally differentiated chondrocytes contribute to bone formation in vivo92
Characterization of a novel X-linked nuclear protein down-regulated in neonatal mouse hypoxic-ischemic encephalopathy, HID-1125
The use of a mouse model to understand the role of SOX9 in campomelic dysplasia and the notochord98
Characterisation of MAD2B114
Analysis of multiple cardiac abnormalities of a mouse mutant Hoxb3lacZ143
Mechanistic insight into chondrocyte adaptation to ER stress106
Aligned chitosan nanofibers for culturing Schwann cells to guide axonal growth40
Identification of novel interactions between viral envelop proteins and activating receptor family of natural killer cells172
Functional characterization of the liver-enriched transcription factor CREB-H138
Computational construction of the downstream network of Pax6 in AD neuronal death model43
Extracellular matrix and stem cell niche in the regenerating planarian140
The relationship of ligamentum flavum changes and developmental spinal stenosis39
Chondroitinase ABC-I and -II crosslinked chitosan beads improve axonal regrowth in CSPG-enriched astrocyte culture69
Differential requirement of suppressor of fused (Su(fu)) in mammalian hedgehog signaling and neural development106
Identifying genetic mutations in patients with Rasopathies using a Next Generation Sequencing Diagnostic Pipeline in Hong Kong126
Sox10 mutation affects inner ear gliogenesis and morphogenesis102
Bone Fracture Healing in Laminopathy-based Premature Aging132
Nitrated chondroitin sulfate proteoglycans in cerebrospinal fluid of patients with amyotrophic lateral sclerosis84
The double-stranded RNA-binding protein PACT activates cytoplasmic viral sensor MDA5 by promoting its oligomerization29
Loss of β-catenin in hypertrophic chondrocytes results in abnormal bone formation114
Modulation of innate antiviral immunity by influenza virus NS1 protein78
Linkage analysis on familial early-onset degenerative disc disease121
Induction of osteo-chondroprogenitors formation by transcription-factor mediated reprogramming process42
Kinesin-1 is necessary for cytokinesis in chondrocytes151
Linkage analysis of familial early-onset degenerative disc disease (DDD)112
Interferon-genhances nitric oxide synthase expression induced by paclitaxel in alveolar macrophages: the roles of ras/mek/erk and NF-kB in signal transduction146
Melatonin inhibits the proliferation of hormone-refractory prostate cancer cells by up-regulating p27 Kip1 expression and down-regulating activated androgen signal transduction via membrane MT1 receptor activation.95
New avenues to malaria diagnosis – nucleic acid aptamers against P. falciparum histidine rich protein 2 and lactate dehydrogenase106
The activity of liver-enriched and growth-suppressive transcription factor CREB-H is tightly regulated by N-linked glycosylation and ubiquitination100
Recovering isoform specific gene regulatory networks from RNA-SEQ data32
Virtually there: a journey to the HKU Medicine Island for teaching and learning45
Mechanism behind the fate commitment of bone marrow-derived schwann cells87
Hypertrophic chondrocytes contribute directly to the osteoblast and osteocyte lineage in endochondral bones in vivo84
Abnormal cell cycle regulation and chondrocyte differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia mutation in COL10A1.117
Development of three-dimensional culture system for bovine nucleus pulposus cells55
Change in NECL family expression profile in cell culture model when NECL1 is knocked down27
Correlation between the nano-structure and the macro-mechanics of the human intervertebral discs105
Identification of therapeutic agents for the treatment of osteoarthritis with the application of high-throughput screening103
Loss of peroxiredoxin Tsa1p induces genome instability through activation of DNA damage checkpoint and elevation of dNTP levels.92
Novel Profile Hidden Markov Model to Predict MicroRNAs and their Targets Simutaneously114
Regulation of NRG3 neurotrophic factor causes instigation on neuritic elongation and surviral by a novel phosphatase PTPN2162
Dynamics of chondroitin sulfotransferase expression for cranial motor neuron migration in rat hindbrain development31
Cellular localization of heparanase in the normal versus injured spinal cord of adult rats108
Hypoxia-related and Stem Cell-like Phenotypes of Young, Adult and Aged Intervertebral Disc Cells106
Role of type II collagen turnover in disc development and degeneration135
Development of a virosome vaccine against aspergillus fumigatus53
Heparanase expression in regenerating peripheral nerves and dorsal root ganglion explant cultures70
Transcriptional control of sensory progenitor specification in the inner ear17
Removal of antagonistic spindle forces can rescue metaphase spindle length and reduce chromosome segregation defects65
Chitosan conduits seeded with bone marrow stromal cell-derived schwann cells enhance regeneration of rat sciatic nerve105
Genetic analyses of matrix protein function and terminal differentiation of hypertrophic chondrocytes111
Nerve guidance channel constructed by Schwann cell seeded aligned chitosan nanofiber70
BDNF-mediated GABAergic transmission in the rat vestibular nucleus regulates the developmental recognition of spatial orientation39
Fibroblast growth factor receptor 1 (FGFR1) regulates terminal differentiation of hypertrophic chondrocytes114
Activation of protein secretory pathway by fusion oncoprotein FUS-CREB3L2 in low-grade fibromyxoid sarcoma77
Heparanase activity facilitates syndecan-1 shedding in airway inflammation132
Bridge-1 utilizes a PDZ-like domain to coactivate E2A-mediated insulin gene transcription121
Developmental Origins of Osteoblasts in Endochondral Bone Formation80
Effects of fluoxetine on the restoration of plasticity in young adult vestibular nucleus108
Addressing the pericellular matrix of reactive astrocytes115
Structural and functional evaluation of allogeneic MSC-based disc regeneration: implications of dosage and stage of degeneration with long-term follow-up102
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions91
Sox10 mutation affects enteric neural crest cell migration in a cell autonomous manner116
New Bone Formation by Injected With Osteogenic Cells Confined in Sodium Alginate Microcapsules120
Phylogenetic analysis of planarian collagens and their roles in regeneration51
Uncovering functions of long-chain polyphosphate in higher eukaryotes: storage and synthesis of polyphosphate in matrix vesicles during mineralization21
Identification and characterization of long-range SOX9 enhancers in limb development39
RAS signalling in Mll-mediated Leukaemia105
The p21/WAF1/Cip1 mediates the anti-mitogenic but not the anti-apoptotic action of epidermal growth factor (EGF) in an epithelial tumor cell line140
Degradation of lung proteoglycans by stimulated neutrophils94
In vitro generation of Schwann cells from mammalian skin for bridging injured nerves147
Towards functional recovery in the injured CNS: Generating oligodendrocyte precursors from bone marrow stromal cells for remyelination99
From Discrete Molecules to Supramolecular Assemblies – An Interplay of Electrostatics, π-π Stacking and Metal-Metal Interactions17
Communication in medical education: harnessing the power of the Internet90
Viral suppression of type I interferon production through PACT targeting32
Defective Self-renewal And Early Cellular Senescence In Premature Aging Mesenchymal Stem Cells83
Functional Analyses of Type IIA Procollagen in Mouse Inner Ear Development89
The effect of severity of degeneration on intervertebral disc regeneration by autologous mesenchymal stem cells122
Id1 upregulates aurora kinase A, induces centrosome abnormalities, polyploidy and disrupts microtubule integrity99
MTI-MMP Supports Development Niche of B Cell Lineage in Bone Marrow85
Abnormal enteric ganglia development in a SOX 10 mouse mutant generated by gene targeting156
Integrative approach for omic data analysis and gene regulatory network construction30
Developmental assembly of neural correlates for head direction102
The Irx3 and Irx5 genes in inner ear development104
Chromosome 10 and 12 loci for late-onset Alzheimer’s Disease: genetic linkage and case-control association studies93
Effects of fluoxetine on the restoration of plasticity in young adult vestibular nucleus47
SELEX in silico59
Genetic linkage analysis of early onset degenerative disc disease in Southern Chinese109
Analysis of mammalian gene expression noise in a negative-feedback loop67
The role of glycosaminoglycans secreted by the astrocyte cell line DI TNC1 in the regulation of neurite outgrowth89
Characteristics of phosphatidylinositol headgroup exchange in rat heart membranes107
MEKK1 phosphorylation of TORC 1 transcriptional coactivator119
Mutant Sox9 exerts context dependent gain-of-function impact in a campomelic dysplasia mouse model95
External fixation fracture model of the mouse femur86
Impact of intracellular clearance of unfolded proteins on chondrocytes cell fate102
The roles of Sox9 and its regulatory elements in campomelic dysplasia36
Protection of cigarette smoke–induced up-regulation of neutrophil elastase by Chinese green tea in rat lung99
The role of FOXM1 and Kaiso in non-small-cell lung carcinoma (NSCLC)95
Deleted in Liver Cancer 2, DLC2, suppresses cell transformation via inhibition of rhoa activity132
The enzymatic mechanism mediating the breakdown of glycogen in hypoxic tumor cells17
Interleukin-1 beta (IL-1β) and osteoprotegrin (OPG) gene polymorphisms are associated with knee osteoarthritis in Chinese33
Role of Epstein-Barr virus-encoded BART microRNAs in viral infection and transformation of nasopharyngeal epithelial cells20
Aligned chitosan nano-fibers for nerve regeneration131
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family90
Study of the Taq I Polymorphism of Vitamin D Receptor gene in Lumbar Disc Degeneration in Chinese104
Lineage extension chondrocytes and the ontogeny of bone cells114
Proheparanase regulates synaptic plasticity of the hippocampus99
The role of SoxE transcription factors in melanoma development162
Activation of nuclear factor kappa B by androgen receptor splice variant AR-V7 in 22Rv1 Castration-resistant prostate cancer cells59
Shape transformation of the nuclear envelope during cell division50
Regulation of AMPA-type glutamate receptor trafficking by proheparanase in synaptic plasticity139
Genomic analysis of the mutant locus in the novel transgenic mouse mutant, yellow submarine (ysb)106
PDSS2 conditional knockout mouse model142
The Role of Indian Hedgehog in Chondrocyte Hypertrophy108
Human cathepsinG-cre mice for myeloid-specific gene targeting111
Altered matrix structure and bone density in collagen X null mice96
A Hoxb3Mouse Mutant with Abnormal Thoracic Body Wall Development120
The Role of SOX10 in the Enteric Neural Crest Development111
Anti-proliferative effects of PDZD2 and its secreted protein sPDZD2 on prostate cancer cells103
Fate and properties of notochordal descendent cells in the intervertebral disc: implication to disc degeneration56
Mapping of a genetic modifier of congenital heart defect in type IIA procollagen deficient mice91
Extracellular Matrix and Membrane-type Matrix metalloproteinase in Development and Diseases30
In vivo analysis of SOX9 by conditionally knock-in of a mutant Sox9, Sox9Y440X, in the notochord128
Nano-structure of collagen fibrils in human intervertebral discs and its correlation with the tissue mechanics160
Cytodifferentiation agent-induced changes in production of sulfated proteoglycans in human colon carcinoma cells86
Special tribute to KT Jeang32
Chondroitin sulfotransferase expression pattern in migrating motor neurons of the rat embryonic hindbrain64
Expression of engrailed-Hoxb5 transcriptional repressor by Wnt1-Cre produces neurocristopathies of pigmentation and enteric nervous system defects in mice106
Adenoviral delivery of RNA decoys restores expression of proapoptotic protein PUMA in nasopharyngeal carcinoma cell by silencing of epstein-barr virus-encoded antiapoptotic miR-BART582
Functional Role of MT1-MMP in FGF Signaling102
Stimulation of k-receptor in cultured heart myoblasts suppresses intracellular cAMP level and elevates intracellular Ca2+ through a pertussis-toxin-sensitive mechanism83
A simple annular puncture model of disc degeneration in the mouse tail102
Single-stranded oligonucleotide-mediated targeted gene repair in mammalian cells89
Illuminating the aetiology of Campomelic dysplasia caused by mutation in the transactivation domain of SOX9124
The regulation of FGF signaling by MT1-MMP in calvarial osteogenesis29
An integrated metalloproteomic analysis depicts the proteomic features of Helicobacter pylori in response to Bi(III)67
N-methyl-D-Aspartate receptor blockade-mediated apoptosis induced GSK activation and increase of TAU phosphorylation in newborn rats139
DNA aptamers as new therapeutic agents against sclerostin, ADAMTS-5 and WWP1 ubiquitin ligase20
Secreted PDZ domain-containing protein 2 (sPDZD2) exerts insulinotropic effects on INS-1E cells via a protein kinase A - dependent mechanism101
Perturbation of Hoxb5 signalling in vagal neural crest cells causes defective development of the enteric nervous system124
Roles of notch and ErbB signaling in the fate commitment of bone marrow-derived Schwann cells28
Functional significance of the AU-rich sequence element in the mRNA of the stress- inducible protein CHOP/Gadd15394
Aptamer-mediated inhibition of sclerostin for osteoporosis therapy127
Analysis of craniofacial defects in Six1/Eya1-associated Branchio-Oto-Renal Syndrome54
The beneficial effects of Qigong and conventional exercise on blood pressure and anthropometric indices in type 2 Chinese diabetic patients145
Yeast TRAMP complex facilitates pre-mRNA splicing134
The role of Sox10 in enteric neural crest cell migration29
The Roles of Sox2 and Sox18 in Hair Follicle Specification87
The use of a mouse model to understand the pathogenesis of campomelic dysplasia caused by the human mutation, Sox9Y440X84
Fabrication of an osteochondral construct with an intact interface using rabbit mesenchymal stem cells (rMSCs) and collagen gel104
The role of SOX9 in ear development96
A proteomic approach to study the molecular mechanisms of the unfolded protein response in the endoplasmic reticulum of chondrocytes97
Cloning and characterization of a Sprague-Dawley rat a-globin gene haplotype132
Regulatory role of perineuronal nets and semaphorin 3A in the developmental maturation of the central vestibular circuitry55
Aptameric inhibition of E3 ubiquitin ligase WWP1 for osteoporosis therapy116
Unfolded protein response leading to cataractogenesis in a microphthalmia cataract mouse mutant86
Transcriptional Control of Sensory Versus Non Sensory Progenitor Specification in the Inner Ear33
Insight into the molecular pathogenesis of campomelic dysplasia revealed by a conditional Sox9 mutant mouse model103
Rational design and development of small interfering RNAs and small hairpin RNAs for inhibition of hepatitis C virus replication83
Regulation of the transferrin receptor expression during phorbol ester-induced differentiation in HK-60 cells106
Resolving the debate about ontogeny of bone cells24
Expression and functional studies of a SH3 domain containing gene family, EEN family, and their implications in leukemogenesis87
Enrichment of committed, chondroitin sulfate-expressing human nucleus pulposus cells over progenitors under alginate encapsulation55
Genome-wide association study of Scoliosis in Southern Chinese51
The Potential Use of Heparinase-generated Heparin Fragments in the Treatment of Bronchiectasis and Chronic Obstructive Pulmonary Disease85
Collagen XXII interacts with integrins via new motifs and links tenocytes to myocytes95
ChIP-Array 2: integrating multiple omics data to construct gene regulatory networks88
Growth inhibitory & facilitatory aspects of chondroitin sulfates in vivo and in vitro86
Signal involved in the switch to fate commitment of bone marrow-derived Schwann cells64
Identification of a novel RHO GTPase activating protein called DLC2, involved in hepatocellular carcinoma93
Functional analysis of SOX10 mutations identified in patients with Waardenburg-Hirschprung Syndrome121
Reduction of Placental Thioredoxin Expression in Diabetic Pregnancies104
The genetic polymorphisms in sex steroid metabolic pathway and risk for sporadic Alzheimer's disease98
Discovering the crucial link for sensory development in the inner ear32
Interplay between ER stress and hypoxia pathways in chondrocytes171
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family96
Generation of induced pluripotent stem (iPS) cells from bone-forming cells115
Upregulation of NF-kB signaling pathway in hepatocellular carcinoma108
Regulation of mouse Hoxb3 gene expression in the anterior neural tube and vagal neural crest84
Abnormal chondrocyte differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia col10a1 mutation106
Computational construction of the downstream network of Pax6 in AD neuronal death model43
Topographical Sagittal Profile in 620 Patients Measured By A Novel Handheld Device92
Beyond the human glucose-6-phosphate dehydrogenase (G6PD) gene: protein structure and function analyses81
Axonal APP interacts with BACE in anterograde transport-dependent manner109
The expression of chondroitin sulfates in rat embryonic hindbrain and their roles on the lateral migration of trigeminal motor neurons79
Towards remyelination therapy with oligodendrocyte precursor and Schwann cells derived from bone marrow stromal cells45
Molecular delineation of the sprague-dawley rat b-globin gene cluster113
The double-stranded RNA-binding protein PACT activates cytoplasmic viral sensor MDA5 by promoting its oligomerization63
Functional study of cerberus-like and noggin proteins: toward a biochemical understanding of BMP antagonists in skeletal disorders93
The influence of progenitor cells in intervertebral disc degeneration and regeneration36
Association of the Asporin D14 allele to lumbar disc degeneration in Chinese and Japanese143
Creation of biological patterns controlled by synthetic genetic circuits56
SARS-CoV S protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection112
Analysis of multiple cardiac abnormalities of a knockout mouse mutant Hoxb3-lacZ81
Mouse model with impaired collagen X degradation at the chondro-osseous junction87
A centrosomal target of HTLV-I Tax on the road to genome instability93
Type IIA procollagen: a positive regulator of nodal signaling during early embryogenesis34
The Interplay between MT1-MMP and ADAMs in Vascular Development38
Signaling mechanisms involved in the inhibition of human prostate cancer cell proliferation by Saw Palmetto (Serenoa repens)102
Dynamic changes of type II collagen in the degenerated murine discs128
Postnatal glutamatergic and GABAergic transmission within the vestibular nucleus is critical for the maturation of canal-related spatial map109
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H137
A novel neural response algorithm for protein function prediction50
ErbB receptor modulation controls the fate commitment of bone marrow-derived Schwann cells80
UHRF1 in Hedgehog signalling and basal cell carcinoma34
Endochondral bone formation and chondrodysplasia: role of collagen X and molecular mechanisms73
Changes in the proteome of the human intervertebral disc in aging and degeneration57
Age-dependent association of the Trp2 allele of the COL9A2 gene with intervertebral disc degeneration in Southern Chinese133
Recurrent substitutions of arginine 789 by cysteine in pro-α1 (II) collagen chains produce spondyloepiphyseal dysplasia congenita100
Sox10 is essential for neural crest invasion in cochlea-vestibular ganglion23
Lack of beta1 integrin results in hemivertebrae development in mice106
Small molecule approach to direct differentiation of human induced pluripotent stem cells to sensory neurons108
Cells in the endplate cartilage contribute to the inner annulus fibrosus in the intervertebral disc161
Investigating the regulatory role of foxmi in cell cycle progression by RNA interference98
In vitro generation of osteo-chondroprogenitors147
Secreted PDZD2 exerts concentration-dependent effects on the proliferation and function of pancreatic beta cells.145
Genetic association studies in lumbar disc degeneration: a systematic review66
Neuronal expression of heparanase 1 and heparanase 273
Assessment of aligner and SNP caller for next generation sequencing and a fast and accurate SNP detection method79
Multidisciplinary disc research123
Localization and the release mechanism of secretin in hypothalamo-pituitary system of the Wistar Rat Rattus novegicus110
Study of polymorphisms of vitamin D receptor gene in lumbar disc degeneration in Chinese84
Hoxb3 deficiency impairs B lymphopoiesis and erythropoiesis in mouse bone marrow94
Modifications in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury84
Genetic modifier(s) of embryonic lethality in type IIA procollagen deficient mice113
Injury-associated changes in glycosaminoglycans and their effects on the regeneration of transected sciatic nerves of guinea pigs104
A centrosomal target of human t-cell leukemia virus oncoprotein tax89
Craniofacial abnormalities caused by ectopic expression of Hoxb3 revealed a network of gene interactions.86
Hoxb3 is involved in the endothelin-1 signaling pathway in patterning the facial branchial arches135
Structural characterization of crystal-active urinary polyanionic macromolecules98
Anti-apoptosis effects of Chinese herbal medicine salvianolic acid B (Sal B) on rat cerebral microvascular endothelial cells154
Effects of reconstituted collagen matrix on fates of mouse embryonic stem cells before and after induction for chondrogenic differentiation129
Heparanase 1 and Heparanase 2 expression in Hippocampal Neurons20
Nucleic acid aptamers for sensing applications: aptamers for diagnosing malaria88
The role of Pax6 in Beta-Amyloid toxicity and Alzheimer’s disease182
Genes and molecular mechanisms in development82
From the marrow to two glial lineages: derivation of oligodendrocyte precursors and Schwann cells from bone marrow stromal cells for remyelination therapy28
The enzyme activity of a membrane-bound isoform of thioredoxin reductase is inhibited by adenine mononucleotide149
Novel plasma-implanted 'smart' metallic materials for orthopedic implants93
Investigating epistasis in degenerative disc disease107
The role of Indian hedgehog in chondrocyte hypertrophy76
Identification of chemical compounds for the treatment of intervertebral disc degeneration with the application of high-throughput screening104
Versatile Metal-Ligand Chromophoric Building Blocks – From Design to Supramolecular Assembly and Functions34
The sortilin-related recentor SORLA is functionally and genetically associated with Alzheimer Disease133
Transcriptional control of chondrocyte differentiation and their adaptation to ER stress in vivo87
The role of Hox genes in otic vesicle patterning and morphogenesis122
A mechanism underlying susceptibility to HBV infection: HBV down-regulate transferase-1 type I interferon receptor 1 via suppressing poly(ADP-ribose)122
Expression of the SOX10 gene in bowel segments of normal and Hirschsprung's disease infants107
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family105
Mouse as a Model for Functional Genetic Studies127
KIF5b is essential for growth plate organization, cytokinesis and chondrocytes differentiation82
Collagen X function and regulation of gene expression97
Towards remyelination therapy with oligodendrocyte precursor derivation from bone marrow stromal cells47
Visualizing the proteome of escherichia coli by labeling E. coli chromosomal genes with fluorescent tags74
Heparin fragments as a potential therapeutic for bronchiectasis and chronic obstructive pulmonary disease99
Analysis of Mll-Een Fusion Gene in Mouse Leukemic Model133
Roles of Progenitor Cells for Intervertebral Disc Regeneration in 'Healer' Mice91
Proteoglycans: From neural cell growth to regeneration113
The Role of Matrix Turnover on Differentiation of Intervertebral Disk Cells47
A Comparison of genomic Instability in Laminopathy-specific Lamin A Mutations78
Cre expression in the node and notochord in transgenic mice driven by FOXA2 minimal nothchord element119
An insertional mutation causing deafness and affecting the regulation of pigmentation in mice96
Chondroitin Sulfate Moieties Restrict Migration of Cranial Motor Neurons in the Developing Hindbrain of Rats101
The MLL-EEN fusion gene leads to maturation arrest and self-renewal of hematopoietic progenitors in ES cells and the development of myeloid leukemia in chimeric mice109
Sox10 is essential for neural crest invasion in cochleo-vestibular ganglion96
Low frequency of TAU mutations and further genetic heterogeneity in FTD117
Putative cellular receptor for secreted PDZ domain-containing protein 2 (sPDZD2) in cancer cells96
Characterisation of steroidogenic acute regulatory protein related lipid transfer domain (START)domain in deleted in Liver Cancer 2(DLC-2)97
The effect of lack of collagen X on fracture healing106
Characterization of Heparanase 1 and Heparanase 2 at Hippocampus47
The development of therapeutic DNA aptamers against various E3 ubiquitin ligase WWP1 truncations96
Biochemical characterization of Gppa-ppx homologues from Mycobacterium tuberculosis117
Expression of chondroitin sulfotransferases in the injured spinal cord84
Effect of inorganic polyphosphate on higher eukaryotic cells92
Mapping a genetic modifier for heart defects in Type IIA procollagen deficient mutant mice84
Regulation of Foxmic By the RAF/MEK/MAPK Pathway84
The molecular basis of Indian hedgehog mutations in digit patterning73
The influence of progenitor cells in intervertebral disc degeneration and regeneration38
Tailored selection of nucleic acid aptamers against sclerostin and aggrecanase for skeletal disease therapeutics35
Kreisler mediates the segmental expression of Hoxb-3 in the mouse hindbrain92
The role of Pax6 in beta-amyloid induced neuronal death101
Collagen-mesenchymal stem cell microspheres for cartilage tissue engineering115
Collagen-mesenchymal stem cell microspheres for regenerative medicine129
The anti-proliferative effects of sPDZD2 on prostate and non-prostate cancer cells116
The identification of enzyme activities that catalyse the reduction of immuoglobulin G interchain disulphides117
Genetic approach to Study the Role of MT1-MMP in Tumor Development in Vivo94
In-Vivo Study of Asporin in Cartilage Tissues82
Bridge: A novel transactivating protein expressed in pancreatic beta cells interacts with E12/E47 proteins86
A reproducible radiological assessment score for fracture healing in mice93
Subcellular localization and post-translational modification of a novel PDZ-domain protein, PIN-1/PAPIN120
Identifying therapeutic chemical agents for osteoarthritis by high throughput screening107
Oligodendrocyte precursors – in vitro derivation from bone marrow stromal cells and use in remyelination therapy34
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation126
A role of proheparanase in synaptic plasticity26
Evaluation of next generation sequencing software in mapping and assembly129
Roles of kinesin-1 mediated intracellular transport in skeletal development146
The role of matrix remodeling in endochondral ossification77
The molecular basis of Indian hedgehog mutations in digit patterning100
Heparan sulfates that upregulate regeneration of post-traumatic sciatic nerves of adult guinea pigs99
Bioluminescent Detection of Nitroreductase Activity and Metals in Live Biological Samples46
Alteration of gene expression with antisense oligonucleotides in whole embryo culture138
Loss of MT1-MMP facilitates iPSCs self-renewal210
Identification of EEN, a novel gene that fuses to HRX in a t (1 1; 1 9) (q23;p 1 3) in acute leukemia137
Neonatal perturbation of KCC2 and NKCC1 co-transporters in the developing vestibular nucleus impairs vestibular functions31
Expression of chondroitin 6-sulfotransferase mRNA and the sulfation product in post-crush sciatic nerves of adult rats95
Hoxb1 cooperates with GL1 to mediate sonic hedgehog signaling in hindbrain neural progenitor cell fate determination104
Interactions of Hox genes during craniofacial development131
Differential roles of RNA-binding proteins TRBP and PACT in RNA silencing and sensing47
Inner ear abnormalities in the novel transgenic mouse mutant, yellow submarine (ysb)103
Using Polyanionic Heparin Mimetics for the treatment of COPD39
Evidence for direct and specific physical interaction between the stress-inducible CHOP mRNA and intracellular proteins100
DNA aptamers can discriminate between closely related aggrecanase drug targets for degenerative disc disease therapy36
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions138
Large scale screening of transcription regulatory sequences recognised by Hox homeodomain proteins90
Regulation of Sox9 function by SUMOylation in avian neural crest development95
Aptamer-based inhibitor of sclerostin for Osteoporosis Therapy135
Spatiotemporal relationship between chondroitin sulfates and chondroitin 6-sulfotransferase in the neuroepithelium during mouse hindbrain development.96
Proheparanase regulates synaptic function in the central vestibular circuitry38
Human T-cell leukemia virus type I oncoprotein tax targets the centrosome103
E3 ubiquitin ligase WWP1 - an intracellar target for aptameric inhibition31
Collagen microspheres: a three-dimensional culture system for notochordal cells135
A novel transcript isoform of STING that suppresses innate antiviral response67
Gli3 repressor is required to mediate the timing of mammalian cochlear hair cell differentiation57
Formation of novel pattern by programming cell motility127
Function genomics and transgenic technology: lessons learnt from manipulating the mouse genome72
Regulation of gene expression in hypertrophic chondrocytes108
Heparan sulphate moieties of syndecan-1 bind neutrophil elastase and modulate access of anti-elastase: Implications in the pathogenesis of bronchiectasis75
Dissecting gene function in the developing inner ear using HOXB2-CRE-mediated activity in transgenic mice96
Type IIA Procollagen: A Positive Regulator of Nodal Signaling During Early Vertebrate Embryogenesis103
Regeneration of nucleus pulposus cells for degenerative disc disorder42
Extracellular matrix and stem cell niche in the regenerating planarian61
Change in perineuronal net of rat vestibular nuclear neurons in development and in injury130
Attentuation of cerebellar plasticity after neonatal perturbation of NMDA receptors in the vestibular nucleus117
The role of Hox genes in dorsoventral patterning and morphogenesis of inner ear98
In vitro aptamer selection against the SARS Coronavirus Helicase91
The hypothalamo-neurohypophsial secretinergic pathway in regulating body water homeostasis117
Gene regulatory network inference from high frequency time series data28
Inhibition of SARS Coronavirus by Bismuth compounds133
Hoxb1 cooperates with Gli to mediate sonic hedgehog signaling in hindbrain neurogenesis93
Genomic instability caused by unprocessed prelamin A contributes to premature aging in mice lacking Zmpste2497
A novel profile hidden Markov model to predict microRNAs and their targets simultaneously156
Procollagen IIA regulates BMP signaling in heart development via a regulatory loop60
Understanding innate immune response to influenza A viruses using reverse genetics and TALEN technology77
Regulation of GADD153 Expression at Post-transcriptional Level by ROS104
Global landscape of histone modifications contributes to cellular identity determination by affecting gene expression dynamics52
Investigation of Antibody-Dependent Enhancement (ADE) of SARS coronavirus infection and its role in pathogenesis of SARS147
The role of chondroitin sulfate moieties on trigeminal motor neuron migration in embryonic rat hindbrain99
Aggrecanase expression, refolding, puriffication and characterization as a foundation for tailored differential SELEX54
Understanding degenerative intervertebral disc disease through devlopmental genetics and genomics105
Genetic study of a large Chinese amyotrophic lateral sclerosis family125
The expression of p21/WAF1/CIP1 is not sufficient to mediate the anti-apoptotic action of Epidermal-Growth-Factor Receptor78
Targeting the SARS coronavirus helicase - three approaches to inhibitor development89
Indian Hedgehog gene in endochondral bone formation97
Activation of the cyclin B1 promoter by FOXM1 is stimulated by the mitogen-activated protein kinase pathway121
Fracture healing in collagen type X deficient mice: abnormalities in structure and mechanical properties of the fracture callus115
SNP-SNP interaction in intervertebral disc disease with genes in the Aggrecan Degradation Pathway122
Structure of RPA32 bound to N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins48
Human T-cell leukemia virus type I oncoprotein Tax targets the centrosome110
Impact of activating ADAMTS-5 in cartilage-related degenerative disorders99
Three novel mutation in exon 3 suggest a possible hot-spot in the RET proto-oncogene for Hirschsprung's disease139
Plasticity of neural correlates for spatial navigation34
Plasticity of GABAergic synapses in the developing vestibular nucleus governs the expression of spatial navigation in mature rats53
Improving the environment for axonal growth with use of recombinant chondroitinase ABC31
Directed Differentiation of Human Induced Pluripotent Stem Cells to Sensory Neurons by Combined Small Molecule Inhibitors32
The role of Hoxb3 in mammalian hindbrain patterning and craniofacial development88
Double stranded RNA-binding protein PACT counteracted by viruses is a cellular partner and activator of RIG-I and MDA5 in innate antiviral response32
Predicting the establishment of hair follicle patterns in the developing mouse43
Divergent routes for derivation of alternative glial cell fate from bone marrow stromal cells of adult rats for remyelination42
Development of novel viral promoter-driven DNA vectors for expression of shRNAs to mediate RNA interference in mammalian cells98
Fate commitment in bone marrow stromal cells derived Schwann cells is dependant on axonal contact129
Novel plasma modified shape memory materials for orthopaedic implantation111
Co-evolution of transcription factor and its binding sites128
The role of Sox 10 on survival and proliferation of enteric neural crest stem cells90
Tissue-specific transcriptional regulation of Sox2 expression in mouse inner ear development79
Quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM) for ultrafast quantitative phase imaging flow cytometry140
Characterization of human bone marrow stromal cells following differentiation into Schwann cells34
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice138
In vivo study of Asporin, a genetic risk factor associated with degenerative disc diseases104
Derivation of Schwann cells from mammalian skin and bone marrow for use in axonal regeneration100
Exploiting aptamer binding properties as a novel diagnostic technology for malaria31
Chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells enhance regeneration of transected sciatic nerves of adult rats99
Roles of Neuregulin 1 Type III in the Ex Vivo Generation of Fate Committed Schwann cells from Bone Marrow Stromal Cells50
Asymptomatic members with SOD1 mutation in a large kindred with familial amyotrophic lateral sclerosis have abnormal water diffusion characterisitcs135
Identification of molecular determinants for efficient H5pp production163
Functionally replicated bioimprint scaffold to support tenocytic differentiation of mesenchymal stem cells53
Regulation of development stage- and tissue- specific expression of the human COL2A1 and mouse COL10A1 genes in transgenic mice106
REV7-mediated polyubiquitination and degradation of human DNA translesion synthesis polymerase REV188
Functional roles for Irx3 and Irx5 in osteoblast differentiation43
Notch signaling mediates the switch to fate commitment of bone marrow-derived Schwann cells45
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans145
The use of aptamer‐conjugated nanoparticles in novel malaria diagnosis platforms42
Development of three-dimesional system for culturing notochordal cells67
Glycosaminoglycan composition of nervous tissues of guinea pig: implications for regenerative capacity83
Type IIA Procollagen as a Modulator of Nodal Signaling30
In vitro selection of DNA and RNA aptamers against sclerostin120
A novel aptamer-mediated approach for degenerative disc disease therapy23
Targeted disruption of the mouse type X collagen gene reveals a role in bone formation88
Commissural projection from the vestibular nucleus in rat embryos: role of chondroitin sulfates106
Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome158
Tracking commissural projections of vestibular neurons in a chondroitin, sulfate-enriched environment of the developing hindbrain89
Sox10 is essential for neural crest invasion in cochlea-vestibular ganglion131
Sufu defines the balance of hindbrain progenitor cells maintenance and differentiation54
Expression of the TRP2 allele of COL9A2 leads to alterations in the mechanical properties of human intervertebral discs115
Rational design and development of small interfering RNAs and small hairpin RNAs for inhibition of hepatitis C virus replication88
Regeneration of degenerated intervertebral disc using allogeneic Mesenchymal stem cells encapsulated in self-assembling peptide hydrogel83
Study on the role of epidermal growth factor in chondrogenesis120
The expression of tissue inhibitor of metalloproteinase (TIMP) during the early stages of healing in both endochondral and intramembranous bone grafts92
Heparan sulfate/syndecan-1 modulates the balance between proteinase and anti-proteinase in bronchiectasis100
Detection of extracellular matrix degradation in intervertebral disc degeneration by diffusion magnetic resonance spectroscopy (DW-MRS)47
The dual role of combinatorial chondoritinase in overcoming the chondroitin sulfate barrier26
Derivation of oligodendrocyte precursors from bone marrow stromal cells: therapeutic potential and developmental origin44
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H105
Cell therapy for remyelination: divergent routes for derivation of alternative glial cell fates from adult bone marrow stromal cells81
Extracellular matrix in planarian regeneration and stem cell maintenance63
Phosphorylation of matrix vesicle components-dependence on alkaline phosphatase79
Computational construction of the downstream network of Pax6 in AD neuronal death model97
Aptamer-directed DNA tweezers65
The Irx3 and Irx5 genes in inner ear development86
Meeting report: Second Singapore Biologics Manufacturing Conference131
Hypertrophic chondrocytes under ER stress utilizes the hypoxia stress signals for survival38
Defining the effects of hypoxia on glycogen metabolism in cancer cells30
CRTC coactivators are required for hepatitis B virus transcription78
H5-type influenza hemagglutinin is functionally recognized by the natural killer activating receptor, Nkp44131
Genetic risks for chronic periodontitis: preliminary data of a genome-wide association study70
Involvement of proheparanase and peri-synaptic heparan sulfate proteoglycan in synaptic plasticity to regulate AMPA-type glutamate receptor trafficking139
Double-stranded RNA-binding protein PACT is a potent activator of RIG-I-dependent innate antiviral response133
An essential role for β1 integrin mediated cell-matrix interactions in the development and maintenance of the nucleus pulposus173
Vitamin D deficiency is associated with depletion of circulating endothelial progenitor cells and endothelial dysfunction in patients with type II diabetes132
An essential role for type IIA procollagen in mouse development89
Sox10 affects enteric neural crest cells migration in a Sox10NGFP/+ mutant85
Establishment of stable infection of Epstein-Barr Virus in premalignant nasopharyngeal epithelial cells106
Identification of multiple isoforms of DLC2, a novel tumor suppressor gene, and their functional characterization in hepatocellular carcinoma95
Regulation of the mouse Hox-B3 gene expression93
Study the function of KIF5B in long bone development93
Potential roles of PDZD2 in prostate cancer pathogenesis119
Detection of plasmodium falciparum lactate dehydrogenase by aptamer-nanoparticle conjugates93
Separation and characterization of urinary glycosaminoglycans of kidney stone formers and normal individuals73
Antiviral activity of cGAMP against RNA virus infection27
Requirement for tax-induced recruitment of TORC family coactivators in transcriptional activation114
Nanomechanical study of vimentin intermediate filament87
Study of the Impact of Sox10 Mutation on the Development of Enteric Nervous System in a Mutant Mouse Model Generated by Gene Targeting96
Epidermal growth factor induced differential calcium signaling patterns in epidermoid cell lines121
Interactions of Hox genes during craniofacial development.95
Stem cells in premature ageing104
RNA transcription affects strand bias in single strand oligonucleotide-mediated mutagenesis128
Chondrocytes from the endplate cartilage contribute to the inner annulus fibrosus in normal and degenerative intervertebral disc30
The regulation of motor neuron migration by differential expression of chondroitin sulfotransferase in rat hindbrain development39
Yeast TRAMP complex facilitates splicing factor recruitment and contributes to optimal slicing efficiency47
Regulation of UHRF1 post transcriptional modifications in DNA damage and cell cycle33
Directed differentiation of bone marrow stromal cells to fate commitment of Schwann cells for remyelination therapy89
Bone marrow stromal cell-derived oligodendrocyte precursor cells: a new perspective in CNS myelin repair89
A cell model system to study the effect of ext mutations on in vitro chondrogenesis100
The mitogen-activated protein kinase pathway promotes mitotic progression through the forkhead box transcription factor foxmi103
Abnormal enteric ganglia development in a Sox10 mouse mutant generated by gene targeting137
Separation and identification of crystal-active urinary glycosaminoglycans110
Identification of metal-binding proteins/Motifs in microorganisms by metalloproteome: an example for Bismuth100
G-quadruplex aptamers inhibit sclerostin for osteoporosis therapy124
Synaptic dysfunction implicated in leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice66
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail133
Impact of extracellular inorganic polyphosphate on osteoblast proliferation, differentiation and apoptosis86
Epigenetic regulation and stem cell contribution in HGPS41
Molecular consequences of Indian hedgehog mutations in chick neural tube84
Acquisition of glutamate receptors in central vestibular synapses is crucial for developmental recognition of spatial orientation145
PHOX2B gene is associated with Hirschsprung's disease132
Procollagen IIA regulates BMP/TGFb signaling in patterning the heart and its major vessels150
Characterizing the re-activated Ihh singling in 13del programming chondrocytes96
4-O-sulfated Chondroitins Contribute to Axon-restrictive Property in Schwann cell-as-trocyte Encounters137
Roles of Prokineticin-1 in enteric nervous system development104
Derivation of Schwann cell from mammalian skin for use in axonal degeneration97
Glycosaminoglycan control of oxalate transport across cultured renal cells113
The study of extracellular matrix and stem cell niche in planarian132
Human Cis-regulatory Module Discovery by Genome Comparison117
Understanding how polymorphisms in cerberus-like result in low bone mineral density118
Genetic control of chondrocyte adaptation to ER stress in chondrodysplasia46
The dual role of combinatorial chondoritinase in overcoming the chondroitin sulfate barrier82
Neural chondroitin sulfates differ from heparan sulfates in effects on regrowth of transected sciatic nerves of adult guinea pigs107
Transcriptional regulation of mitotic checkpoint gene MAD1by p5395
A source of restrictive chondroitin sulfates-in encounters of schwann cells and astrocytes in vitro97
A splicing mutation in the ext2 gene affects messenger RNA stability in a family with hereditary multiple exostoses124
UHRF1 in Basal Cell Carcinoma35
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations67
Upregulation of nitrated chondroitin sulfate proteoglycans in reactive astrocytes and cerebrospinal fluid of patients with amyotrophic lateral sclerosis91
Molecular basis for increased bone formation in a mouse expressing mutant type X collagen123
Developing vestibular neurons display altered commissural projections with depletion of chondroitin sulfates of the hindbrain matrix115
Stem Cells and Aging50
Selection, validation and delivery of DNA aptamers against infectious disease targets144
Functional analysis of a secreted PDZ-containing protein sPDZD2133
Immunostimulatory function of the defective interfering RNA of Measles virus35
Investigating the role of Sox9 in human neural stem cells143
Identification of a functional variant in CHST3 associated with the susceptibility for lumbar disc degeneration114
Aptamers against polyphosphate kinase 2 (PPK2) from mycobacterium tuberculosis as a potential approach of novel anti-tuberculosis therapy123
Generation of mouse notochord cell lines for the study of notochord function during intervertebral disc development151
Overcoming the chondroitin sulphate barrier in injured nerve: the efficacy of chondroitinase ABC treatment and the potency of disaccharide products45
Aptamer-based piezoelectric quartz crystal biosensor for the SARS coronavirus helicase102
Optimization of guide RNA scaffold design for multiplexed gene editing82
Induction of osteo-chondroprogenitors formation during transcription factor-mediated reporgramming process54
Increased 6-sulfated chondroitins correlate with upregulated expression of chondroitin 6-transferase mRNA in post-crush sciatic nerves of adult rats.97
Understanding Hindbrain Neurogenesis by Analysis of a Hoxb3Transgenic Mouse Mutant SL2121
Semaphorin 3A and chondroitin sulfate proteoglycan networks of perineuronal nets regulate developing central vestibular circuitry39
sPDZD2, a novel modulator in Hedgehog signaling104
Genome-wide Haplotype Association Mapping in mice identifies a genetic variant in CER1 associated with bone mineral density and fracture in southern Chinese women115
Impact of activating ADAMTS-5 in cartilage-related degenerative disorders109
A novel 3-dimensional culture system for mouse embryonic stem cells117
Nucleic acid aptamers against ADAMTS as a new therapeutic approach against degenerative disc disease114
New selection and delivery approaches for nucleic acid aptamers against proteomic targets102
The role of CREB in Ras-induced expression of interleukin 8140
Fine mapping candidate loci for nasopharyngeal carcinoma (NPC) in southern Chinese specifically linked to EBV aetiopathogenesis116
Transcriptional profiling of enteric neural crest cells101
Investigation of the functions and specificities of mouse myosin va isoforms119
Characterization of an enhancer element for establishing transgenic mouse models for enteric nervous system development126
The role and imaging of PAX6 in a mouse model of alzheimer's disease52
Genome-wide association study of adolescent idiopathic scoliosis in southern Chinese131
Over-expression of Hoxb3 affects inner ear neurogenesis98
Suppressor of fused (Su(fu)) plays domain specific function in orchestrating the maintenance and differentiation of hindbrain neural progenitor pools139
MT1-MMP regulates Notch signalling to maintain B lymphocyte development35
Antiviral effect of DNA aptamers binding H5N1 virus nucleoprotein112
Specific inhibition of protein disulphide reductase activity of a 60kda rat liver protein by adenine nucleotides78
Different effects of chondroitin and heparan sulphates on the regenerative efficacy of transected sciatic nerves of adult guinea pigs82
Astroglial chondroitin sulfate proteoglycans modulate growth and differentiation of cortical neurons on astrocytes in vitro115
Targeting the polyphosphate kinase 2 with aptamer-based inhibitors as an approach to Tuberculosis Therapy115
How has genetics research altered our understanding of degenerative disc disease: Implications for intervertebral disc regeneration136
Abnormal enteric nervous system development in a Sox10-NGFP mouse mutant210
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans157
FastPval: a fast and memory efficient program to calculate very low p-values from empirical distribution30
Cell quantity and degenerative stage dependent effect of allogeneic mesenchymal stem cells on regeneration of intervertebral disc140
Negative regulation of RIG-1 mediated IRF3 activation by TAK139
Astrocytic proteoglycans regulate neuronal adhesion and growth84
Can stem cells home to the injured intervertebral disc via intravenous infusion? A murine model57
Interplay between ER stress and hypoxia pathways in chondrocytes47
Fate commitment of bone marrow-derived Schwann cells is guided by Notch and ErbB signaling26
Targeted genome editing of Epstein-Barr virus by CRISPR/Cas9 technology in human cells251
The association of disc degeneration based on magnetic resonance imaging and the presence of low back pain89
Mll-Een affects early lineage commitment of embryonic stem cells and causes maturation arrest of myeloid progenitors87
Abnormal enteric ganglia development in a Sox10 mouse mutant generated by gene targeting99
Quantitative characterization of mesenchymal cell aggregation process25
PCR amplification of alleles at locus D17S5: population genetic study in Hong Kong Chinese and detection of allelic loss in patients with hepatocellular carcinoma101
Understanding the Function of the SEDL Gene and the Molecular Pathogenesis of Spondyloepiphyseal Dysplasia Tarda99
Isolation and characterization of cell subpopulation with stem cell properties in human and monkey intervertebral disc (ivd)173
Nitrogen plasma modified nickel titanium alloy for orthopaedic implantation: long-term in vivo study128
DNA aptamer-mediated recognition of malaria diagnostic target Plasmodium lactate dehydrogenase – structure, discrimination and application33
Transgenic mice expressing human epidermal growth factor show stunted growth146
In vivo functional analysis of SOX9 by conditional expression of a mutant Sox9, Sox9Y440X, in the notochord97
Abnormal enteric nervous system development in a Sox10-NGFP mouse mutant158
Molecular consequences of Indian hedgehog mutations causing brachydactylies113
Role of collagen X in fracture repair109
Role of IHH signaling in the progression of digit joint formation146
Synaptojanin, an inositol phosphatase, is a target for three different MLL fusion partners109
Migratory behaviours of sacral neural crest cells in the hindgut of mouse embryos as shown by live cell imaging93
Defects in cochlear structure and function in the Sox9Y440X campomelic dysplasia mouse model122
Kinesin-1 is involved in chondrocytes interaction with extracellular matrix54
Prelamin A Induces Cellular Senescence by Activating Heterochromatin Formation86
Generation of induced pluripotent stem (iPS) cells from bone-formating cells110
Reduced neuronal nitric oxide production from KIF5B-deficiency mice77
Trinations aging symposium137
Semaphorin 3A associated with chondroitin sulfates on perineuronal nets regulates developmental maturation of the central vestibular circuitry34
Endocannabinoid regulates developmental plasticity of central vestibular synapses and vestibular behaviors in rats37
Association of lumbar disc degeneration with type IX collagen polymorphism in Chinese151
Hypertrophic chondrocytes survive ER stress by maintaining glycolysis and mitochondrial membrane poloarity37
Peer generated MCQs to assess and support for learning in a Problem Based Learning Programme117
p70 S6 kinase is a regulator of ovarian cancer metastasis via crosstalk between P-cadherin-beta1-integrin signaling axes51
Chondrocytes survive ER stress caused by unfolded proteins via re-programming121
Improving method for malaria detection – an aptamer approach108
A fast and accurate SNP detection algorithm for next-generation sequencing data81
Ptpn21, a positive mediator which promotes ErbB4 and suppresses cell survival110
The Identification of Regulatory Element(s) in the Promoter of the Thioredoxin Reductase gene100
Light coat and circling (LCC) and yellow submarine (YSB) mutants are Sox2 conditional null models during hair morphogenesis144
Cadherin 2 as human notochordal cell marker and its expression pattern in disc degeneration77
Bridge acts as a coactivator of E2A-Mediated regulation of the insulin gene89
NKCC1 and KCC2 cotransporters are required in postnatal maturation of the vestibular system33
MEKK1-induced phosphorylation and activation of TORC1 transcriptional coactivator80
Roles of perineuronal matrix in developmental plasticity of the central vestibular system49
Differential patterns of developing vestibular commissural projection with digestion of chondroitin sulfates120
Collagen-mesenchymal stem cell microspheres for cartilage tissue engineering170
Chinese green tea protects cigarette smoke-induced up-regulation of neutrophil elastase in rat lung119
Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression19
Development of DNA aptamers against Treponema denticola75
Type IIA procollagen: A positive regulator of nodal signaling during embryogenesis94
Construction of new DNA vectors based on promoters of Epstein-Barr virus-encoded small RNAs for expression of small hairpin RNAs in mammalian cells100
Heparan Sulfates and Heparanase in the Mineralizing Matrix of Developing Mouse Growth Plate85
Loss of MT1-MMP affects CNS development28
Genome-wide association study of Degenerative Disc Disease (DDD)156
Tspyl2 is involved in cellular stress response and brain function90
In-vitro effect of bronchiectatic sputum sol on ICAM-1 expression in bronchial epithelial cells105
Unraveling the role of type X collagen during fracture repair98
Molecular cloning characterization and purification of rat pro- and mature heparanase87
Bridging of transected sciatic nerves of adult guinea pigs with soluble heparan sulfates speeds up nerve regeneration94
Identification of a genetic modifier of CHD in Type IIA procollagen deficient mutant mice suggests a dynamic regulatory system in cardiac development117
Genetic risk factors for intervertebral disc degeneration121
Towards a universal aptamer diagnostics platform22
Use of Bicistronic Constructs to Over-Express the Epidermal Growth Factor Precursor107
Selection and delivery of aptamers against the SARS Coronavirus Helicase104
Chitosan fibers for culturing aligned Schwann Cells for nerve regeneration41
The involvement of perineuronal semaphorin 3A and chondroitin sulfates in regulating maturation of the central vestibular circuitry25
Research on the genetic basis of human split hand/foot malformation 123
Towards understanding genetic and molecular etiology of campomelic dysplasia33
Activation of NLRP3 inflammasomes by severe acute respiratory syndrome coronavirus 3a protein47
The regulatory role of proheparanase in synaptic plasticity at the hippocampus90
Both HIF-1α and HIF-2α are present in prenatal and postnatal nucleus pulposus cells64
Factors underlying improved efficacy of chondroitin sulphate lyases in overcoming chondroitin sulphate barriers for nerve repair and regeneration125
Analysis of multiple cardiac abnormalities of a knockout mouse mutant Hoxb3Hoxb3lacZ100
Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity91
Notch signaling mediates the switch to fate commitment of bone marrow-derived Schwann cells39
Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons92
The activity of N-(4-hydroxyphenyl) retinamide in nasopharyngeal carcinoma cells123
Lithium ion alters Ins (1,4,5) P3 production and mobilisation of intracellular free calcium in K-agoinst stimulated rat ventricular myocytes119
Uncovering essential gene function for sensory organ development in the mammalian inner ear114
The association of osteoprotegerin gene polymorphism with knee osteoarthritis in Chinese population135
Candidate gene study of polymorphisms of interleukin-1 in lumbar disc degeneration145
An improved method for cell traction force measurement135
Depletion of SUV39 ameliorates progeroid phenotypes and extends lifespan in accelerated aging mice27
Development of Salmonella-mediated Oral Vaccine against Avian Influenza Viruses H5N195
The Trp2 allele of Collagen IX is an age-dependent risk factor for the development and severity of intervertebral disc degeneration114
Structural studies of intermediates along the reaction pathway of ADP-ribosyl cyclase81
Comprehensive Analysis of MRI-Phenotypes Provides New Insights into Lumbar Disc Degeneration for Genetic Studies75
Molecular basis for increased bone formation in a mouse expressing mutant type X collagen97
Recombinogenic tagging reveals dynamic compartmentalization of the escherichia coli proteome99
Juxtacrine signalling via Notch and ErbB receptors in the switch to fate commitment of bone marrow-derived Schwann cells114
In vitro aptamer selection against the SARS coronavirus helicase and their intracellular delivery89
Heparanase upregulation in astrocytes and macrophages recruited to the injured spinal cord128
The interplay between EPS8 and FOXM1 in carcinogenesis37
Role of membrane Type-I matrix metalloproteinase (MT1-MMP) in mouse intestinal development36
Uncoupled endochondral ossification in transgenic mice expressing type X collagen with mutations in the NC1 domain122
Directed differentiation of human induced pluripotent stem cell to sensory neurons by combined small molecule inhibitors103
Generation of early HIV-1 specific intermediated B cell line based on improved B cells immortalization followed with magnetic isolation from PBMC of a health donor36
Exploring the mechanisms of salmonella-induced reduction of cancer metastasis85
Impaired chromatin modification interferes with double-strand break repair in accelerated aging syndrome106
Axonal trajectories of the vestibular nuclei in the developing rat embryo145
Regulation of phosphorylation of c-jun N-terminal kinases (JNKs) in neonatal mouse hypoxic ischemic encephalopathy model114
Sox2 is Required for Sensory Organ Development in the Mammalian Inner Ear118
Prevalence, psychosocial and physical health correlates of psychotic disorders in Hong Kong: the Hong Kong Mental Health Morbidity Survey1112
Sox proteins and inner ear development129
Oriented Schwann Cells Culture on Aligned Chitosan Nanofibers for Axonal Growth Guidance27
The molecular bases underlying the inner ear phenotypes of mouse mutants, yellow submarine (YSB)and light coat and circling (LCC)133
Potential signaling mechanisms of the secreted PDZ domain-containing protein 2 (sPDZD2) in tumor suppression101
Three genes in the aggrecan degradation pathway act synergistically to predispose to degenerative disc disease96
Context dependent impact of the Y440X campomelic dysplasia Sox9 mutation145
Regulatory role of neuronal proheparanase in synaptic plasticity54
Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres95
Characterization of intracellular transportation in KbcU-mutant purkinje cells83
Cells in the endplate contribute to the maintenance and repair of the inner annulus fibrosus51
Heparan sulfates and heparanase at the mineralization front of the developing growth plate107
Matrix remodeling during intervertebral disc growth and degeneration detected by multichromatic fast staining242
Influenza A virus NS1 protein targets double-stranded RNA binding protein PACT to suppress innate antiviral response51
An essential role for type IIA procollagen in heart development102
Generation of oligodendrocyte precursors from bone marrow stromal cells for remyelination therapy31
Endocannabinoid regulates the efficacy of vestibular inhibitory synapses contributing to the expression of gravity-detection behavior in developing rats50
Signals involved in the switch to fate commitment of bone marrow-derived Schwann cells23
Intervertebral disc degeneration on MRI is associated with low back pain: a population-based study87
NRProF: Neural Response Based Protein Function Prediction Algorithm28
Generation of a mouse model to study ADAMTS-5 as a genetic risk factor for intervertebral disc degeneration79
Mechanisms of hereditary factors127
MT1-MMP in FGF Signaling81
Isthmin, a novel extracellular regulator of nodal signaling113
Prevalence of intervertebral disc degeneration in Hong Kong-a magnetic resonance imaging study of 977 volunteers153
The role of Pax6 in beta-amyloid-induced neuronal apoptosis116
In silico mapping of quantitative trait loci affecting bone mineral density in mice107
Genotype-phenotype relationships in the regulation of skeletal formation and growth76
Over-expression of epidermal growth factor precursor in vitro and in vivo157
Cholesterol biosynthesis is a potential pathway involved in the degeneration of the annulus fibrosus100
Postnatal maturation of the vestibular circuit for gravity detection by under the regulation of perineuronal chondroitin sulfates and semaphorin 3A36
Insights into the molecular pathogenesis of campomelic dysplasia caused by mutations in Sox925
Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in the rat90
Spatiotemporal expression of cadherin 2 in the notochordal nucleus pulposus during development and aging of murine intervertebral disc110
Activity-dependent GABAergic synaptic plasticity in medial vestibular neurons of rats143
Studies on the molecular mechanism of morphogenetic defects in brachydactyly type A-192
Aptamer-mediated Inhibition of Mycobacterium tuberculosis Polyphosphate Kinase 2236
Cholesterol and genetics of Alzheimer's disease91
Aptamers against P. falciparum lactate dehydrogenase as a new approach to malaria diagnosis112
NRProF: neural response based protein function prediction algorithm90
Developing vestibular neurons display differential commissural projection patterns with digestion of chondroitin sulfates108
A Novel Sox10-NGFP mouse model of Waardenburg-Hirschsprung Syndrome159
Molecular and mutation analysis of hereditary multiple exostoses131
Potential role of Atg16L1 in autophagic vesicle trafficking in primary cultured neurons18
Inhibition of E3 ubiquitin ligase WWP1 with selective DNA Aptamers95
Towards remyelination therapy: divergent routes for derivation of alternative glial cell fate from bone marrow stromal cells of adult rats39
Molecular basis for growth plate abnormalities in a mouse model with schmid metaphyseal chondrodyplasia118
Yeast pre-mRNA splicing is facilitated by a RNA surveillance complex122
Growth inhibition and morphological alterations induced by hexamethylene bisacetamide on a human colon cancer cell line108
Genome-wide Haplotype Association Mapping (HAM) in mice leads to an identification of a genetic variant in CER1 associated with bone mineral density in premenopausal women116
Subcellular localization of sars coronavirus orf8 protein89
Neutrophil elastase changes its binding partner following neutrophil degranulation in airway inflammation79
Control of cell fate and lineages in skeletal development27
Chondroitin sulfate moieties expressed by migrating motor neurons in explant cultures of the rat hindbrain96
Analysis of mouse Hox-2 gene regulation by transgenic mice110
Neuronal proheparanase regulates synaptic function of the central vestibular system78
Fine-tuning of notochord midline position via cell-matrix interactions52
Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study172
Sox2 regulates hair type specification and hair cycle68
Role of ATM signaling in PALB2-dependent DNA damage responses26
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of DNA damage checkpoint and elevation of dNTP levels100
Expression patterns of heparanase in normal and injured rat spinal cord107
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations64
Expression of chondroitin sulfotransferases in cranial motor neurons in the embryonic rat hindbrain80
Virtually there: a journey to the HKU Medicine Island for teaching and learning39
KIF5b is essential for growth plate organization and cytokinesis77
ER-stress signaling and chondrocyte differentiation in mice120
Correlating protein structure with disease - understanding the mechanism of SEDT117
Stem Cells - Whats and Hows60
Sox2 dosage defines the specification and survival of sensory neurons in the inner ear40
The identification of sequence elements that mediate stabilization of the CHOP/Gadd153 mRNA by N-(4-hydroxyphenyl)retinamide (4HPR/fenretinide)101
Intervertebral disc regeneration by use of autologous mesenchymal stem cells, an experimental model in rabbits106
Transient enrichment of 6-sulphated isomers of chondroitin in post-crush sciatic nerves of adult guinea pigs116
Identification of distinct DNA elements from the human a1(II) collagen gene directing tissue specific expression during development81
REV7-mediated polyubiquitination and degradation of human REV1101
Discriminatory targeting of ADAMTS aggrecanases for high-specificity therapeutics development for degenerative disc disease24
Sufu controls the number and cell fate of hindbrain progenitors63
Alleviating ER stress in chondrocytes: molecular strategies and the developmental cost of recovery76
Suppressor of fused controls the maintenance of neural progenitor pools and regulates notch pathway activity in rhombomere 428
Nerve conduit constructed by aligned chitosan nanofibers for directing axonal growth in nerve regeneration94
Reduced neuronal nitric oxide production in KIF5b-deficiency mice118
Functional characterisation reveals PTPN21 as a positive mediator of NRG3, a potential risk factor in Schizophrenia121
Development of Three-Dimensional Culture System for Maintenance of Bovine Nucleus Pulposus Cells67
Vasostatin gene therapy suppressed lung tumor growth and metastasis using adeno-associated virus pseudotype 5 vector116
Crystal-suppressive modulators of separated urinary polyanions79
Eya1 regulates notch signaling in branchial epithelium during craniofacial development47
Cre-transgenic mouse line for conditional gene knockout in retinal rod bipolar cells120
Heterogeneity of Neural Progenitor Cells in the Adult Mouse Spinal Cord117
TNF-a in bronchial secretions of patients with bronchiectasis stimulates neutrophil-mediated degradation of lung proteoglycans115
Study of DNA aptamers binding H5N1 virus nucleoprotein95
Towards the understanding of nickel trafficking in helicobacter pylori: expression and characterization of a his-rich protein, HPN122
Genetic risk prediction for common diseases using genetic markers from Genome-Wide Association studies23
Identification and characterization of long-range SOX9 enhancers in limb development46
N-(4-hydrxophenyl)retinamide induces up-regulation of GADD153 in a nasopharyngeal carcinoma cell line139
New plasma surface-treated memory alloys: Towards a new generation of "smart" orthopaedic materials165
The role of autophagy in determining chondrocyte cell fates in response to ER stress106
Homeobox gene HOXB5 is required in the embryonic development of the enteric nervous system114
An essential role for Sox2 in sensory organ development in the mammalian inner ear86
Investigating epistasis in degenerative disc disease99
Polyphosphate regulates interleukin-11 levels of SaOS-2 cells41
Regulation of p16INK4a expression by the forkhead transcription factor FOXM1122
Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression29
Latent membrane protein 1 interacts with the proliferation and apoptotic pathways in epithelial cells107
Aptamer library resampling23
Ectopic expression of Hoxb-3 in rhombomere 4 suppresses Hoxb-1 expression135
Genetics study in intervertebral disc degeneration.141
Assessing Clusters and Motifs from Gene Expression Data136
MMP14 regulates the lineage progression of hypertrophic chondrocytes47
Analysis of craniofacial defects in Six1/Eya1-associated Branchio-Oto-Renal Syndrome89
Molecular cloning and characterization of chondroitin 6-sulfotransferase (c6st) in crush-injured rat sciatic nerves118
Repair of osteochondral defects with collagen-mesenchymal stem cell microspheres in a rabbit model101
The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell73
Role of endocannabinoid and GABAA receptor in modulating synaptic plasticity in the vestibular nucleus of postnatal rats32
Characterization and mutational analysis of an exopolyphosphatase from Mycobacterium smegmatis99
Generation of Mutant Mouse Models for Studying the Role of Sox10 Functional Domains in Enteric Nervous System Development86
Coping With Stress in Hypertrophic Chondrocytes: The Role of PERK Pathway182
Correlation between developmental chondroitin sulfate pattern and the upregulation of chondroitin 6-sulfotransferase mRNA expression in the embryonic hindbrain102
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda112
Chromosomal tagging of the C terminals of E. Coli gene products79
Differential and overlapping expression of SOX2 and SOX9 in inner ear development82
Overcoming axon-restrictive chondroitin supphates with chondroitin sulphate lyases152
The role of Prkci in the development of notochord93
GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations and chromosome states45
The potential role of Simian Virus 40 polyA sequence (SV40 polyA) to mediate stress-inducible mRNA translation98
In vivo study of Asporin, a genetic risk factor for osteoarthritis and degenerative disc disease84
Molecular Basis for Gerodermia Osteodysplastica, a Prematured Aging Disorder87
Integration of factors and pathways facilitating chondrocyte adaptation to ER stress110
A method for morphological localization of cell and matrix vesicle-associated alkaline phosphatase105


TotJulAugSepOctNovDecJanFebMarAprMayJun
2016/2017201902810122614061196401410551125829104793722502295
2017/20181723914721047839132993236516119052330135012401533
2018/201926606287780079540426513914262838171033144034602787
2019/202021000450715826212033880183325484219580585863749
2020/202181994213772504671851707125022822105241033670493872121
2021/202213413400000000000
Ever167163