Developing AI-guided trajectorial demarcation of retinal-nerve-fibre-layer defect to reveal progressive axonal degeneration in glaucoma before detectable thinning
Grant Data
Project Title
Developing AI-guided trajectorial demarcation of retinal-nerve-fibre-layer defect to reveal progressive axonal degeneration in glaucoma before detectable thinning
Principal Investigator
Dr Lam, Ka Ngai Alexander
(Principal Investigator (PI))
Co-Investigator(s)
Professor Leung Kai Shun
(Co-Investigator)
Duration
36
Start Date
2024-10-01
Amount
1500000
Conference Title
Developing AI-guided trajectorial demarcation of retinal-nerve-fibre-layer defect to reveal progressive axonal degeneration in glaucoma before detectable thinning
Keywords
optic neuropathy, glaucoma, diagnosis, progression, OCT
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
11221916
Grant Type
Health and Medical Research Fund 2022
Funding Year
2022
Status
On-going
Objectives
To compare reliability and reproducibility of retinal-nerve-fiber-layer (RNFL) defect parameter measurements from AI guided trajectorial demarcation and manual demarcation by trained graders; and to determine diagnostic performance of using defect parameters derived from AI-guided demarcation as novel biomarkers to detect glaucoma and evaluate its progression.