Sequential Transarterial Chemoembolization and Stereotactic Body Radiotherapy followed by Immunotherapy (START-FIT) as Downstaging Treatment for Liver Transplantation: A prospective, single-arm, phase II Trial
Grant Data
Project Title
Sequential Transarterial Chemoembolization and Stereotactic Body Radiotherapy followed by Immunotherapy (START-FIT) as Downstaging Treatment for Liver Transplantation: A prospective, single-arm, phase II Trial
Principal Investigator
Professor Chiang, Chi Leung
(Principal Investigator (PI))
Co-Investigator(s)
Dr Chiu Wan Hang Keith
(Co-Investigator)
Dr Chan Sik Kwan
(Co-Investigator)
Professor Lo Cheuk Lam Regina
(Co-Investigator)
Professor Chan Albert Chi Yan
(Co-Investigator)
Duration
36
Start Date
2024-11-01
Amount
1314332
Conference Title
Sequential Transarterial Chemoembolization and Stereotactic Body Radiotherapy followed by Immunotherapy (START-FIT) as Downstaging Treatment for Liver Transplantation: A prospective, single-arm, phase II Trial
Keywords
TACE, SBRT, Immunotherapy, START-FIT, Downstaging
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
11221726
Grant Type
Health and Medical Research Fund 2022
Funding Year
2022
Status
On-going
Objectives
While our team pioneered that novel combination of sequential transarterial chemoembolization, stereotactic body radiotherapy followed by immunotherapy (START-FIT) is promising, its role as downstaging treatment for liver transplantation (LT) remains to be explored. We aim to investigate the efficacy and safety of START-FIT as a downstaging treatment for LT in a prospective trial.