Development of Bacterial Pseudaminic Acid-based Vaccine to Combat Infections caused by Multidrug Resistant Bacteria

View Statistics Email Alert RSS Feed

Grant Data
Project Title
Development of Bacterial Pseudaminic Acid-based Vaccine to Combat Infections caused by Multidrug Resistant Bacteria
Principal Investigator
Professor Li, Xuechen   (Co-Principal Investigator (Co-PI) (for projects led by other university))
Co-Investigator(s)
Dr Chen Sheng   (Project coordinator)
Duration
48
Start Date
2024-04-01
Amount
1428571
Conference Title
Development of Bacterial Pseudaminic Acid-based Vaccine to Combat Infections caused by Multidrug Resistant Bacteria
Keywords
Pseudaminic Acid, Vaccine, ESKAPE, MDR pathogens, Bacterial infections
Discipline
MicrobiologyBiochemical Engineering
Panel
Biology and Medicine (M)
HKU Project Code
R1011-23
Grant Type
Research Impact Fund (RIF) 2023/24
Funding Year
2023
Status
On-going
Objectives
(1) Evaluation of current Pse-based vaccine on toxicity, host tolerance and protection of infections caused by different clinically important Pse producing bacterial pathogens(2) Conduct scale-up production of Pse through biosynthesis or semi-biosynthesis approaches(3) Develop scalable Pse-based vaccines to combat infections caused by different bacterial pathogens