Impact of early sepsis care with the National Early Warning Score 2-guided Sepsis Hour-1 Bundle in the emergency department: a hybrid type 1 effectiveness-implementation pilot study (NEWS-1 Trial Pilot Study)

Professor Lam, Pui Kin   (Principal Investigator (PI))

Wan Kuang An   (Co-Investigator)

Professor Lam Wendy Wing Tak   (Co-Investigator)

Kwok Wai Shing David   (Co-Investigator)

Kwong Po Yin   (Co-Investigator)

Dr Lau Eric Ho Yin   (Co-Investigator)

Dr Lui Chun Tat   (Co-Investigator)

Dr Hung Kevin KC   (Co-Investigator)

Professor Sridhar Siddharth   (Co-Investigator)

Professor Rainer Timothy Hudson   (Co-Investigator)

18

2022-12-01

1344100

Impact of early sepsis care with the National Early Warning Score 2-guided Sepsis Hour-1 Bundle in the emergency department: a hybrid type 1 effectiveness-implementation pilot study (NEWS-1 Trial Pilot Study)

Sepsis, Sepsis Hour-1 Bundle, National Early Warning Score 2, emergency department, antibiotics

Medicine, Dentistry and Health

19201161

Health and Medical Research Fund - Full Grant

2022

On-going

To evaluate the effect of the Surviving Sepsis Campaign (SSC) Hour-1 Bundle in reducing mortality in adult patients presenting to the emergency department (ED) with a clinical diagnosis of infection and a National Early Warning Score 2 (NEWS2) ≥ 5, and to determine the barriers to and facilitators of its implementation.