Interactions between genetic risk and sedentary behavior for cardiovascular disease and type 2 diabetes: Using integrated prospective cohorts from UK Biobank and China Kadoorie Biobank

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Grant Data
Project Title
Interactions between genetic risk and sedentary behavior for cardiovascular disease and type 2 diabetes: Using integrated prospective cohorts from UK Biobank and China Kadoorie Biobank
Principal Investigator
Dr Kim, Youngwon   (Principal Investigator (PI))
Co-Investigator(s)
Dr Au Yeung Shiu Lun Ryan   (Co-Investigator)
Mr Sharp Stephen J   (Co-Investigator)
Dr Wijndaele Katrien   (Co-Investigator)
Duration
24
Start Date
2022-01-01
Amount
906009
Conference Title
Interactions between genetic risk and sedentary behavior for cardiovascular disease and type 2 diabetes: Using integrated prospective cohorts from UK Biobank and China Kadoorie Biobank
Presentation Title
Keywords
cardiovascular disease, China Kadoorie Biobank, Gene-environment interaction, sedentary behavior, type 2 diabetes, UK biobank
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
06200087
Grant Type
HMRF Research Fellowship Scheme
Funding Year
2021
Status
On-going
Objectives
Sedentary behavior (SB) is a key risk factor for cardiovascular disease(CVD) and type 2 diabetes (T2D).However, no research has explored whether the beneficial impact of reducing SB on disease risk applies to everyone, regardless of their genetic predisposition. /this research aims to investigate whether associations of SB with incident CBD and T2D differ by level genetic predisposition to T2D.