RIsk factors in Mother and Autism spectrum disorder in offspring (RIMA)


Grant Data
Project Title
RIsk factors in Mother and Autism spectrum disorder in offspring (RIMA)
Principal Investigator
Professor Wong, Ian Chi Kei   (Principal Investigator (PI))
Co-Investigator(s)
Professor Murphy Declan G   (Co-Investigator)
Dr Lai Chia Cheng Edward   (Co-Investigator)
Mr Man Kenneth   (Co-Investigator)
Professor Wing Yun Kwok   (Co-Investigator)
Professor Coghill David Rockwell   (Co-Investigator)
Professor Ip Patrick   (Co-Investigator)
Dr Luo Hao   (Co-Investigator)
Dr Leung Wing Cheong   (Co-Investigator)
Dr Zhang Qingpeng   (Co-Investigator)
Dr Shin Ju Young   (Co-Investigator)
Duration
33
Start Date
2022-01-01
Completion Date
2025-10-14
Amount
1056156
Conference Title
RIsk factors in Mother and Autism spectrum disorder in offspring (RIMA)
Keywords
Autism spectrum disorder, Machine learning, Maternal Health, Paediatrics, Risk factors
Discipline
PaediatricsEpidemiology
Panel
Biology and Medicine (M)
HKU Project Code
17114921
Grant Type
General Research Fund (GRF)
Funding Year
2021
Status
Completed
Objectives
1 Estimate the annual prevalence and incidence of clinically diagnosed autism spectrum disorder (ASD) and associated comorbidities in the four participating sites i.e. Hong Kong, the United Kingdom, Taiwan, and South Korea. 2 Investigate the effect of maternal modifiable risk factors on the risk of ASD and associated comorbidities in the offspring. 3 Investigate the effect of early childhood characteristics on the risk of development of ASD and associated comorbidities. 4 Develop and validate a predictive algorithm for ASD and associated comorbidities using machine learning.