The role of endoglandular trophoblast in placenta development and its association with preeclampsia

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Grant Data
Project Title
The role of endoglandular trophoblast in placenta development and its association with preeclampsia
Principal Investigator
Professor Chiu, Chi Ngong   (Principal Investigator (PI))
Co-Investigator(s)
Dr Lee Cheuk Lun   (Co-Investigator)
Professor Ng Ernest Hung Yu   (Co-Investigator)
Professor Yeung William Shu Biu   (Co-Investigator)
Duration
36
Start Date
2021-01-01
Completion Date
2023-12-31
Amount
1182701
Conference Title
The role of endoglandular trophoblast in placenta development and its association with preeclampsia
Keywords
endometrial gland, organoid, Preeclampsia, Pregnancy, Trophoblast
Discipline
ReproductionPhysiology
Panel
Biology and Medicine (M)
HKU Project Code
17115320
Grant Type
General Research Fund (GRF)
Funding Year
2020
Status
Completed
Objectives
1 To study the differentiation of human EVT into endoglandular trophoblast 2 To study the action of endoglandular trophoblast on EVT invasion and vascular remodeling via modulating endometrial gland secretion 3 To compare the endoglandular trophoblast phenotype and endometrial gland secretion from normotensive and PE pregnancy