Structural and Functional Dissection of a Novel TRIM28 Protein Complex


Grant Data
Project Title
Structural and Functional Dissection of a Novel TRIM28 Protein Complex
Principal Investigator
Professor Qian, Chengmin   (Principal Investigator (PI))
Co-Investigator(s)
Professor Zhou Zhongjun   (Co-Investigator)
Duration
47
Start Date
2020-08-01
Amount
1195542
Conference Title
Structural and Functional Dissection of a Novel TRIM28 Protein Complex
Keywords
DNA-binding specificity, POGK, transcriptional regulation, TRIM28, X-ray crystallography
Discipline
Structural BiologyBiochemistry
Panel
Biology and Medicine (M)
HKU Project Code
17126720
Grant Type
General Research Fund (GRF)
Funding Year
2020
Status
On-going
Objectives
1 To solve the crystal structure of TRIM28/POGK complex. 2 To determine DNA-binding specificity of POGK.