Peripheral immunological response to treatment with checkpoint inhibitor in recurrent/metastatic nasopharyngeal carcinoma and correlation with clinical response and adverse effects
Grant Data
Project Title
Peripheral immunological response to treatment with checkpoint inhibitor in recurrent/metastatic nasopharyngeal carcinoma and correlation with clinical response and adverse effects
Principal Investigator
Professor Kwong, Dora Lai Wan
(Principal Investigator (PI))
Co-Investigator(s)
Professor Guan Xin-Yuan
(Co-Investigator)
Dr Kam Ngar Woon
(Co-Investigator)
Dr Lam Ka On
(Co-Investigator)
Professor Lee Victor Ho Fun
(Co-Investigator)
Duration
27
Start Date
2018-09-06
Amount
1125384
Conference Title
Peripheral immunological response to treatment with checkpoint inhibitor in recurrent/metastatic nasopharyngeal carcinoma and correlation with clinical response and adverse effects
Keywords
Epstein-barr virus, immunopathology, immunotherapy, Nasopharyngeal, recurrent/metastitic
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
05162186
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2017
Status
Completed
Objectives
To evaluate peripheral immunological response to programmed cell death-1 (PD-1) inhibitor treatment in nasopharyngeal carcinoma (NPC) and correlate the immunological response with clinical outcomes to identify biomarkers predicting for efficacy and adverse effects.