Gut-derived flagellin ameliorates diet-induced dyslipidemia by upregulating apolipoprotein-A1

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Grant Data
Project Title
Gut-derived flagellin ameliorates diet-induced dyslipidemia by upregulating apolipoprotein-A1
Principal Investigator
Dr Woo, Wai Hong Connie   (Principal Investigator (PI))
Co-Investigator(s)
Professor Xu Aimin   (Co-Investigator)
Professor Tso Patrick   (Co-Investigator)
Duration
32
Start Date
2018-04-01
Amount
1052996
Conference Title
Gut-derived flagellin ameliorates diet-induced dyslipidemia by upregulating apolipoprotein-A1
Presentation Title
Keywords
Atherosclerosis, Flagellin, gut microbiota, HDL, lipoproteins, TLR5
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
05162606
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2017
Status
Completed
Objectives
The objectives of this study are to elucidate the relationship between gut-derived flagellin, HDL level and apolipoprotein-A1 (apoA1) production, and identify the underlying molecular mechanism