The mechanobiology of obesity
Grant Data
Project Title
The mechanobiology of obesity
Principal Investigator
Professor Xu, Aimin
(Principal Investigator (PI))
Co-Investigator(s)
Dr Demolombe Sophie
(Co-Investigator)
Ms Patel Amanda
(Co-Investigator)
Dr Honore Eric
(Co-Investigator)
Ms Moro Celne
(Co-Investigator)
Dr Hui Xiaoyan
(Co-Investigator)
Dr Wang Baile
(Co-Investigator)
Mr Arhatte Malika
(Co-Investigator)
Ms Duval Helene
(Co-Investigator)
Duration
48
Start Date
2018-01-01
Amount
90000
Conference Title
The mechanobiology of obesity
Presentation Title
Keywords
mechanobiology of obesity
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
F-HKU701/17
Grant Type
France/Hong Kong Joint Research Scheme - Travel Grants
Funding Year
2017
Status
On-going
Objectives
1. To examine whether and how the mechanosensitive channel Piezo1 in adipocytes influences expression and release of adipokines; 2. To study whether adipocyte-selective deletion of Piezo1 affects metabolic dysfunction and obesity-related inflammatory responses. 3. To explore the role of Piezo1 in the modulation of adiponectin release by 3 polyunsaturated fatty acid or enriched-diet.