Does methylphenidate treatment increase seizure risk in children and adolescents with Attention Deficit Hyperactivity Disorder?

Dr Ip, Patrick   (Principal Investigator (PI))

Professor Sham Pak Chung   (Co-Investigator)

Professor Wong Ian Chi Kei   (Co-Investigator)

Mr Man Keng Cheung Kenneth   (Co-Investigator)

Professor Cross Helen   (Co-Investigator)

Dr Chan Esther Wai Yin   (Co-Investigator)

Dr Fong Daniel Yee Tak   (Co-Investigator)

Dr Chan Meanne   (Co-Investigator)

24

2017-08-01

360000

Does methylphenidate treatment increase seizure risk in children and adolescents with Attention Deficit Hyperactivity Disorder?

ADHD, Methylphenidate, Seizure

Paediatrics,Pharmacology/Toxicology

Biology and Medicine (M)

17108717

General Research Fund (GRF)

2017

Completed

1 To estimate the incidence of seizure in patients receiving MPH treatment. 2 To investigate the association between MPH and the risk of incident seizure in treated patients. 3 To investigate the association between MPH and the risk of recurrent seizure in treated patients. 4 To investigate the influence of MPH’s interaction with concurrent antidepressant and antipsychotic use on the risk of incident and recurrent seizures.