Selective overexpression of SIRT1 in adipose tissue protects adiponectin deficiency induced liver injury

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Grant Data
Project Title
Selective overexpression of SIRT1 in adipose tissue protects adiponectin deficiency induced liver injury
Principal Investigator
Professor Wang, Yu   (Principal Investigator (PI))
Co-Investigator(s)
Dr Xu Cheng   (Co-Investigator)
Duration
33
Start Date
2017-04-01
Amount
959608
Conference Title
Selective overexpression of SIRT1 in adipose tissue protects adiponectin deficiency induced liver injury
Presentation Title
Keywords
adiponectin, clusterin, fatty liver, liver injury, SIRT1
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
04151796
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2016
Status
Completed
Objectives
This present study aims to investigate the mechanisms underlying the cross-talk between adiponectin, SIRT1 and clusterin in adipose tissue and how this effect contributes to the liver function.