Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads
Grant Data
Project Title
Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads
Principal Investigator
Professor Che, Chi Ming
(Principal Investigator (PI))
Co-Investigator(s)
Professor Lin Marie Chia-Mi
(Co-Investigator)
Professor Lau Tai Chu
(Co-Investigator)
Dr Sun Wai Yin Raymond
(Deputy project coordinator)
Dr Lau Chi Keung
(Co-Investigator)
Dr Leung Chung Hang
(Co-Investigator)
Professor Vanhoutte Paul Michel Georges Remi
(Co-Investigator)
Dr Siu Fung Ming Annie
(Co-Investigator)
Professor Wang Yu
(Co-Investigator)
Professor Poon Ronnie Tung Ping
(Co-Investigator)
Dr Ma Dik Lung
(Co-Investigator)
Duration
30
Start Date
2010-03-01
Amount
8999900
Conference Title
Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads
Presentation Title
Keywords
Metal-Based Anti-Cancer Drug
Discipline
Pharmacology/Toxicology
Panel
Physical Sciences (P)
HKU Project Code
ITS/134/09FP
Grant Type
Innovation and Technology Support Programme (Tier 2)
Funding Year
2009
Status
Completed
All Publications
| Title | Author(s) | Issue Date | |
|---|---|---|---|
Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes Journal:Angewandte Chemie - International Edition | 2011 | ||
Osmium(vi) complexes as a new class of potential anti-cancer agents Journal:Chemical Communications | 2011 | ||
Organoplatinum(II) complexes with nucleobase motifs as inhibitors of human topoisomerase II catalytic activity Journal:Chemistry - An Asian Journal | 2010 | ||
| 2011 | |||
Cyclometalated platinum(ii) complexes as topoisomerase IIα poisons Journal:Chemical Communications | 2011 | ||
Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents Journal:Chemical Communications | 2011 | ||
Anticancer dirhodium(ii,ii) carboxylates as potent inhibitors of ubiquitin-proteasome system Journal:Chemical Science | 2012 |