Characterization of Novel Adaptor Proteins Involved in Regulating Insulin Sensitivity and Glucose Homeostasis: from Molecular Mechanism to Physiological Implication
Grant Data
Project Title
Characterization of Novel Adaptor Proteins Involved in Regulating Insulin Sensitivity and Glucose Homeostasis: from Molecular Mechanism to Physiological Implication
Principal Investigator
Professor Xu, Aimin
(Principal Investigator (PI))
Co-Investigator(s)
Professor Kraegen Edward W.
(Co-Investigator)
Professor Liu Feng
(Co-Investigator)
Duration
36
Start Date
2010-01-01
Amount
1500000
Conference Title
Characterization of Novel Adaptor Proteins Involved in Regulating Insulin Sensitivity and Glucose Homeostasis: from Molecular Mechanism to Physiological Implication
Presentation Title
Keywords
Akt, diabetes, glucose metabolsim, insulin resistance, signal transduction
Discipline
Diabetes/Metabolism,Signal Transduction
Panel
Biology and Medicine (M)
HKU Project Code
HKU 781309M
Grant Type
General Research Fund (GRF)
Funding Year
2009
Status
Completed
All Publications
Title | Author(s) | Issue Date | |
---|---|---|---|
APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice Journal:Proceedings of the National Academy of Sciences of the United States of America | 2012 |