Browsing by Author Madeira, Brian

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 中
Showing results 1 to 3 of 3
TitleAuthor(s)Issue Date
 
Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK
Journal:Bioorganic and Medicinal Chemistry Letters
Laufer, RadoslawLi, Sze WanLiu, YongNg, GraceLang, YunhuiFeher, MiklosBrokx, RichardBeletskaya, IrinaHodgson, RichardMao, GuodongPlotnikova, OlgaAwrey, Donald E.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaMadeira, BrianFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.
2016
 
The discovery of orally bioavailable tyrosine threonine kinase (TTK) inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as anticancer agents
Journal:Journal of Medicinal Chemistry
Liu, YongLang, YunhuiPatel, Narendra KumarNg, GraceLaufer, RadoslawLi, Sze WanEdwards, LouiseForrest, BryanSampson, Peter B.Feher, MiklosBan, FuqiangAwrey, Donald E.Beletskaya, IrinaMao, GuodongHodgson, RichardPlotnikova, OlgaQiu, WeiChirgadze, Nickolay Y.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaMadeira, BrianFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.
2015
 
The discovery of polo-like kinase 4 inhibitors: Identification of (1 R,2 S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1 H -indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a potent, orally active antitumor agent
Journal:Journal of Medicinal Chemistry
Sampson, Peter B.Liu, YongForrest, BryanCumming, GrahamLi, Sze WanPatel, Narendra KumarEdwards, LouiseLaufer, RadoslawFeher, MiklosBan, FuqiangAwrey, Donald E.Mao, GuodongPlotnikova, OlgaHodgson, RichardBeletskaya, IrinaMason, Jacqueline M.Luo, XunyiNadeem, VincentWei, XinKiarash, RezaMadeira, BrianHuang, PingMak, Tak W.Pan, GuohuaPauls, Henry W.
2015
Showing results 1 to 3 of 3