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Conference Paper: Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study

TitleOsteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study
Authors
Issue Date2004
Citation
Transactions - 7Th World Biomaterials Congress, 2004, p. 893 How to Cite?
Abstract
The viability and osteogenic differentiation potentials of mesenchymal stem cells (MSC) encapsulated in alginate microcapsules for bone formation were studied. Goat MSCs were established and cultured in vitro for the study. The cell samples were divided into two groups, monolayer and microcapsule cultures. The MTS colorimetric assay was used to evaluate cell viability in both monolayer and alginate microcapsule groups. In monolayer cultures, MSCs were found to maintain a fibroblast-like morphology. It was also observed that the encapsulated MSCs, without any genetic modifications, retained the ability to differentiate into osteoblasts after appropriate stimulation in vitro.
Persistent Identifierhttp://hdl.handle.net/10722/96328
References

 

Author Affiliations
  1. The University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorAbbah, ASen_HK
dc.contributor.authorLu, WWen_HK
dc.contributor.authorLiu, WGen_HK
dc.contributor.authorChan, Den_HK
dc.contributor.authorLuk, KDKen_HK
dc.contributor.authorCheung, KMCen_HK
dc.contributor.authorLeong, JCYen_HK
dc.date.accessioned2010-09-25T16:30:25Z-
dc.date.available2010-09-25T16:30:25Z-
dc.date.issued2004en_HK
dc.identifier.citationTransactions - 7Th World Biomaterials Congress, 2004, p. 893en_HK
dc.identifier.urihttp://hdl.handle.net/10722/96328-
dc.description.abstractThe viability and osteogenic differentiation potentials of mesenchymal stem cells (MSC) encapsulated in alginate microcapsules for bone formation were studied. Goat MSCs were established and cultured in vitro for the study. The cell samples were divided into two groups, monolayer and microcapsule cultures. The MTS colorimetric assay was used to evaluate cell viability in both monolayer and alginate microcapsule groups. In monolayer cultures, MSCs were found to maintain a fibroblast-like morphology. It was also observed that the encapsulated MSCs, without any genetic modifications, retained the ability to differentiate into osteoblasts after appropriate stimulation in vitro.en_HK
dc.languageengen_HK
dc.relation.ispartofTransactions - 7th World Biomaterials Congressen_HK
dc.titleOsteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro studyen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailLu, WW:wwlu@hku.hken_HK
dc.identifier.emailChan, D:chand@hkucc.hku.hken_HK
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_HK
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_HK
dc.identifier.authorityLu, WW=rp00411en_HK
dc.identifier.authorityChan, D=rp00540en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.authorityCheung, KMC=rp00387en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-13844299214en_HK
dc.identifier.hkuros87289en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-13844299214&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.spage893en_HK
dc.identifier.epage893en_HK
dc.identifier.scopusauthoridAbbah, AS=6506315482en_HK
dc.identifier.scopusauthoridLu, WW=7404215221en_HK
dc.identifier.scopusauthoridLiu, WG=35269689700en_HK
dc.identifier.scopusauthoridChan, D=7402216545en_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK
dc.identifier.scopusauthoridCheung, KMC=7402406754en_HK
dc.identifier.scopusauthoridLeong, JCY=35560782200en_HK

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