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Conference Paper: Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study
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TitleOsteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study
 
AuthorsAbbah, AS1
Lu, WW1
Liu, WG1
Chan, D1
Luk, KDK1
Cheung, KMC1
Leong, JCY1
 
Issue Date2004
 
CitationTransactions - 7Th World Biomaterials Congress, 2004, p. 893 [How to Cite?]
 
AbstractThe viability and osteogenic differentiation potentials of mesenchymal stem cells (MSC) encapsulated in alginate microcapsules for bone formation were studied. Goat MSCs were established and cultured in vitro for the study. The cell samples were divided into two groups, monolayer and microcapsule cultures. The MTS colorimetric assay was used to evaluate cell viability in both monolayer and alginate microcapsule groups. In monolayer cultures, MSCs were found to maintain a fibroblast-like morphology. It was also observed that the encapsulated MSCs, without any genetic modifications, retained the ability to differentiate into osteoblasts after appropriate stimulation in vitro.
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorAbbah, AS
 
dc.contributor.authorLu, WW
 
dc.contributor.authorLiu, WG
 
dc.contributor.authorChan, D
 
dc.contributor.authorLuk, KDK
 
dc.contributor.authorCheung, KMC
 
dc.contributor.authorLeong, JCY
 
dc.date.accessioned2010-09-25T16:30:25Z
 
dc.date.available2010-09-25T16:30:25Z
 
dc.date.issued2004
 
dc.description.abstractThe viability and osteogenic differentiation potentials of mesenchymal stem cells (MSC) encapsulated in alginate microcapsules for bone formation were studied. Goat MSCs were established and cultured in vitro for the study. The cell samples were divided into two groups, monolayer and microcapsule cultures. The MTS colorimetric assay was used to evaluate cell viability in both monolayer and alginate microcapsule groups. In monolayer cultures, MSCs were found to maintain a fibroblast-like morphology. It was also observed that the encapsulated MSCs, without any genetic modifications, retained the ability to differentiate into osteoblasts after appropriate stimulation in vitro.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationTransactions - 7Th World Biomaterials Congress, 2004, p. 893 [How to Cite?]
 
dc.identifier.epage893
 
dc.identifier.hkuros87289
 
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dc.identifier.spage893
 
dc.identifier.urihttp://hdl.handle.net/10722/96328
 
dc.languageeng
 
dc.relation.ispartofTransactions - 7th World Biomaterials Congress
 
dc.relation.referencesReferences in Scopus
 
dc.titleOsteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study
 
dc.typeConference_Paper
 
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Author Affiliations
  1. The University of Hong Kong