File Download

There are no files associated with this item.

Supplementary

Conference Paper: Asymptomatic members with SOD1 mutation in a large kindred with familial amyotrophic lateral sclerosis have abnormal water diffusion characterisitcs

TitleAsymptomatic members with SOD1 mutation in a large kindred with familial amyotrophic lateral sclerosis have abnormal water diffusion characterisitcs
Authors
Issue Date2006
PublisherThe International Society for Magnetic Resonance in Medicine (ISMRM)
Citation
The International Society for Magnetic Resonance in Medicine 14th Scientific Meeting & Exhibition (ISMRM2006). Seattle, WA, 6-12 May 2006 How to Cite?
AbstractDTI was carried out in FALS/SALS patients and familial members with SOD1 mutation (AFALS) who may be in a pre-symptomatic phase of ALS. The changes in FA and TT were investigated in CBT/CST and in whole brain. In FALS/SALS, diffusion pattern changes were found in cerebral peduncle, internal capsule, sub-cortical white matter, cerebellum and frontal lobe while in AFALS, abnormal pattern could also be detected in the cerebral peduncle, cerebellum and frontal lobe but with a smaller extent. Our study indicates that DTI can show early diffusion changes in members with SOD1 mutation in FALS prior to symptom-onset.
Persistent Identifierhttp://hdl.handle.net/10722/96302

 

DC FieldValueLanguage
dc.contributor.authorNg, MCen_HK
dc.contributor.authorHo, JTen_HK
dc.contributor.authorHo, SLen_HK
dc.contributor.authorLee, Ren_HK
dc.contributor.authorLi, Gen_HK
dc.contributor.authorSong, Yen_HK
dc.contributor.authorChan, KHen_HK
dc.contributor.authorCheng, TSen_HK
dc.contributor.authorYang, ESen_HK
dc.contributor.authorLeong, LYen_HK
dc.date.accessioned2010-09-25T16:29:38Z-
dc.date.available2010-09-25T16:29:38Z-
dc.date.issued2006en_HK
dc.identifier.citationThe International Society for Magnetic Resonance in Medicine 14th Scientific Meeting & Exhibition (ISMRM2006). Seattle, WA, 6-12 May 2006-
dc.identifier.urihttp://hdl.handle.net/10722/96302-
dc.description.abstractDTI was carried out in FALS/SALS patients and familial members with SOD1 mutation (AFALS) who may be in a pre-symptomatic phase of ALS. The changes in FA and TT were investigated in CBT/CST and in whole brain. In FALS/SALS, diffusion pattern changes were found in cerebral peduncle, internal capsule, sub-cortical white matter, cerebellum and frontal lobe while in AFALS, abnormal pattern could also be detected in the cerebral peduncle, cerebellum and frontal lobe but with a smaller extent. Our study indicates that DTI can show early diffusion changes in members with SOD1 mutation in FALS prior to symptom-onset.-
dc.languageengen_HK
dc.publisherThe International Society for Magnetic Resonance in Medicine (ISMRM)-
dc.relation.ispartofThe International Society for Magnetic Resonance in Medicine Scientific Meeting & Exhibition (ISMRM)en_HK
dc.titleAsymptomatic members with SOD1 mutation in a large kindred with familial amyotrophic lateral sclerosis have abnormal water diffusion characterisitcsen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailHo, SL: slho@hku.hken_HK
dc.identifier.emailSong, Y: songy@hkucc.hku.hken_HK
dc.identifier.emailChan, KH: chankaho@netvigator.comen_HK
dc.identifier.authoritySong, Y=rp00488en_HK
dc.identifier.hkuros120391en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats