File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Palpable asymmetrical thickening of the breast: A clinical, radiological and pathological study

TitlePalpable asymmetrical thickening of the breast: A clinical, radiological and pathological study
Authors
Issue Date2001
PublisherBritish Institute of Radiology - BJR. The Journal's web site is located at http://bjr.birjournals.org
Citation
British Journal Of Radiology, 2001, v. 74 n. 881, p. 402-406 How to Cite?
AbstractWhile management protocols for a discrete palpable breast lump are standardized in most centres, the approach to an area of palpable asymmetrical thickening in the breast has seldom been addressed. A diagnostic algorithm for palpable asymmetrical thickening of the breast was prospectively evaluated in 116 Oriental women, followed by a retrospective review of their mammograms and histology specimens. Most women (86%) were pre-menopausal and 82% complained of a lump. The thickening eventually resolved spontaneously in 93 (80%) women. None of these 93 women developed cancer at a median follow-up of 41 months. A total of 9 (7.8%) cancers were found in the series of 116 women, including two with a lobular component. The occurrence of cancer was more likely when the woman was older than 43 years or when the thickening was marked (p<0.04). Mammographic review showed correlation of the palpable thickening with localized increase in breast tissue density and/or microcalcifications in 18% of cases. Histology review suggested fibrosis as an explanation for the clinical presentation. Although most cases of thickening tend to resolve with time, a significant number of cancers present in this way. A diagnostic approach with early and liberal imaging and biopsy for high risk women is required.
Persistent Identifierhttp://hdl.handle.net/10722/88593
ISSN
2015 Impact Factor: 1.84
2015 SCImago Journal Rankings: 0.834
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, KLen_HK
dc.contributor.authorHo, LWCen_HK
dc.contributor.authorLeung, EYFen_HK
dc.contributor.authorKhoo, USen_HK
dc.date.accessioned2010-09-06T09:45:25Z-
dc.date.available2010-09-06T09:45:25Z-
dc.date.issued2001en_HK
dc.identifier.citationBritish Journal Of Radiology, 2001, v. 74 n. 881, p. 402-406en_HK
dc.identifier.issn0007-1285en_HK
dc.identifier.urihttp://hdl.handle.net/10722/88593-
dc.description.abstractWhile management protocols for a discrete palpable breast lump are standardized in most centres, the approach to an area of palpable asymmetrical thickening in the breast has seldom been addressed. A diagnostic algorithm for palpable asymmetrical thickening of the breast was prospectively evaluated in 116 Oriental women, followed by a retrospective review of their mammograms and histology specimens. Most women (86%) were pre-menopausal and 82% complained of a lump. The thickening eventually resolved spontaneously in 93 (80%) women. None of these 93 women developed cancer at a median follow-up of 41 months. A total of 9 (7.8%) cancers were found in the series of 116 women, including two with a lobular component. The occurrence of cancer was more likely when the woman was older than 43 years or when the thickening was marked (p<0.04). Mammographic review showed correlation of the palpable thickening with localized increase in breast tissue density and/or microcalcifications in 18% of cases. Histology review suggested fibrosis as an explanation for the clinical presentation. Although most cases of thickening tend to resolve with time, a significant number of cancers present in this way. A diagnostic approach with early and liberal imaging and biopsy for high risk women is required.en_HK
dc.languageengen_HK
dc.publisherBritish Institute of Radiology - BJR. The Journal's web site is located at http://bjr.birjournals.orgen_HK
dc.relation.ispartofBritish Journal of Radiologyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAge Factorsen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAlgorithmsen_HK
dc.subject.meshBiopsy, Needleen_HK
dc.subject.meshBreast Diseases - diagnosis - etiologyen_HK
dc.subject.meshBreast Neoplasms - diagnosis - etiologyen_HK
dc.subject.meshCalcinosis - diagnosis - etiologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFibrosisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMammographyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPremenopauseen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshRemission, Spontaneousen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshRisk Factorsen_HK
dc.titlePalpable asymmetrical thickening of the breast: A clinical, radiological and pathological studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1285&volume=74&spage=402&epage=406&date=2001&atitle=Palpable+asymmetrical+thickening+of+the+breast:+a+clinical,+radiological+and+pathological+studyen_HK
dc.identifier.emailKhoo, US:uskhoo@hkucc.hku.hken_HK
dc.identifier.authorityKhoo, US=rp00362en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11388987-
dc.identifier.scopuseid_2-s2.0-0034954947en_HK
dc.identifier.hkuros59754en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034954947&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume74en_HK
dc.identifier.issue881en_HK
dc.identifier.spage402en_HK
dc.identifier.epage406en_HK
dc.identifier.isiWOS:000169434300002-
dc.publisher.placeUnited Kingdomen_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats