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Article: Use of gonadotrophin releasing hormone (GnRH) antagonist (Cetrotide) during ovarian stimulation for in-vitro fertilization treatment: Multiple doses and single dose

TitleUse of gonadotrophin releasing hormone (GnRH) antagonist (Cetrotide) during ovarian stimulation for in-vitro fertilization treatment: Multiple doses and single dose
Authors
KeywordsGnRH antagonist
IVF
Multiple doses
Single dose
Issue Date2001
PublisherBlackwell Publishing Asia.
Citation
Journal Of Obstetrics And Gynaecology Research, 2001, v. 27 n. 5, p. 261-265 How to Cite?
AbstractObjectives: To report preliminary experience in using the GnRH antagonist (Cetrotide) and to compare the multiple dose and single dose protocols. Methods: Fifteen patients received multiple doses and another 10 patients received the single dose protocol of GnRH antagonist during ovarian stimulation for IVF treatment. Outcome measures included the duration/dosage of gonadotrophin and number of oocytes aspirated. Results: All patients had successful oocyte retrieval after the hCG injection. The single dose group had a significantly shorter duration of gonadotrophin but fewer frozen embryos than the multiple dose group. Conclusions: Both protocols were effective in preventing premature LH surges. The stimulation regimen was simplified by reducing the total treatment period, the dosage and duration of gonadotrophin. There may be differences in ovarian responses between the two protocols.
Persistent Identifierhttp://hdl.handle.net/10722/87444
ISSN
2015 Impact Factor: 1.091
2015 SCImago Journal Rankings: 0.521
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, EHYen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:29:44Z-
dc.date.available2010-09-06T09:29:44Z-
dc.date.issued2001en_HK
dc.identifier.citationJournal Of Obstetrics And Gynaecology Research, 2001, v. 27 n. 5, p. 261-265en_HK
dc.identifier.issn1341-8076en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87444-
dc.description.abstractObjectives: To report preliminary experience in using the GnRH antagonist (Cetrotide) and to compare the multiple dose and single dose protocols. Methods: Fifteen patients received multiple doses and another 10 patients received the single dose protocol of GnRH antagonist during ovarian stimulation for IVF treatment. Outcome measures included the duration/dosage of gonadotrophin and number of oocytes aspirated. Results: All patients had successful oocyte retrieval after the hCG injection. The single dose group had a significantly shorter duration of gonadotrophin but fewer frozen embryos than the multiple dose group. Conclusions: Both protocols were effective in preventing premature LH surges. The stimulation regimen was simplified by reducing the total treatment period, the dosage and duration of gonadotrophin. There may be differences in ovarian responses between the two protocols.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia.en_HK
dc.relation.ispartofJournal of Obstetrics and Gynaecology Researchen_HK
dc.subjectGnRH antagonisten_HK
dc.subjectIVFen_HK
dc.subjectMultiple dosesen_HK
dc.subjectSingle doseen_HK
dc.titleUse of gonadotrophin releasing hormone (GnRH) antagonist (Cetrotide) during ovarian stimulation for in-vitro fertilization treatment: Multiple doses and single doseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1341-8076&volume=27&issue=5&spage=261&epage=265&date=2001&atitle=Use+of+Gonadotrophin+Releasing+Hormone+(GnRH)+antagonist+(Cetrotide)+during+ovarian+stimulation+for+in-vitro+fertilization+treatment:+Multiple+doses+and+single+doseen_HK
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityNg, EHY=rp00426en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11776508-
dc.identifier.scopuseid_2-s2.0-0035194984en_HK
dc.identifier.hkuros65365en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035194984&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume27en_HK
dc.identifier.issue5en_HK
dc.identifier.spage261en_HK
dc.identifier.epage265en_HK
dc.identifier.isiWOS:000173334300005-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridNg, EHY=35238184300en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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