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Article: Female urethral adenocarcinoma arising from urethritis glandularis

TitleFemale urethral adenocarcinoma arising from urethritis glandularis
Authors
KeywordsFemale
Intestinal metaplasia
Urethral adenocarcinoma
Urethritis glandularis
Issue Date2000
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygyno
Citation
Gynecologic Oncology, 2000, v. 79 n. 3, p. 511-514 How to Cite?
AbstractIntroduction. Female urethral adenocarcinoma is extremely rare and more than one tissue of origin has been suggested other than the Skene's gland. Immunohistochemistry with cytokeratins (CK) 7 and 20 is used to define the origin of the tumor. Case report. A 72-year-old woman presented with a 2-cm polypoid tumor at the external urethral meatus and bleeding. Wide local excision and bilateral inguinal lymphadenectomy were performed. Postoperative convalescence was uneventful. It was a poorly differentiated mucinous adenocarcinoma without direct urothelial involvement. There were focal areas of intestinal metaplasia. The tumor cells were positive for CK 7 and 20 and negative for prostate-specific antigen. Discussion. This case provides supportive evidence that mucinous urethral adenocarcinoma may arise from malignant transformation of urethritis glandularis. (C) 2000 Academic Press.
Persistent Identifierhttp://hdl.handle.net/10722/87438
ISSN
2015 Impact Factor: 4.198
2015 SCImago Journal Rankings: 2.284
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, YMen_HK
dc.contributor.authorKaLeung Cheng, Den_HK
dc.contributor.authorNgaYin Cheung, Aen_HK
dc.contributor.authorYuenSheung Ngan, Hen_HK
dc.contributor.authorWong, LCen_HK
dc.date.accessioned2010-09-06T09:29:39Z-
dc.date.available2010-09-06T09:29:39Z-
dc.date.issued2000en_HK
dc.identifier.citationGynecologic Oncology, 2000, v. 79 n. 3, p. 511-514en_HK
dc.identifier.issn0090-8258en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87438-
dc.description.abstractIntroduction. Female urethral adenocarcinoma is extremely rare and more than one tissue of origin has been suggested other than the Skene's gland. Immunohistochemistry with cytokeratins (CK) 7 and 20 is used to define the origin of the tumor. Case report. A 72-year-old woman presented with a 2-cm polypoid tumor at the external urethral meatus and bleeding. Wide local excision and bilateral inguinal lymphadenectomy were performed. Postoperative convalescence was uneventful. It was a poorly differentiated mucinous adenocarcinoma without direct urothelial involvement. There were focal areas of intestinal metaplasia. The tumor cells were positive for CK 7 and 20 and negative for prostate-specific antigen. Discussion. This case provides supportive evidence that mucinous urethral adenocarcinoma may arise from malignant transformation of urethritis glandularis. (C) 2000 Academic Press.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygynoen_HK
dc.relation.ispartofGynecologic Oncologyen_HK
dc.subjectFemaleen_HK
dc.subjectIntestinal metaplasiaen_HK
dc.subjectUrethral adenocarcinomaen_HK
dc.subjectUrethritis glandularisen_HK
dc.subject.meshAdenocarcinoma - etiology - metabolismen_HK
dc.subject.meshAgeden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunohistochemistryen_HK
dc.subject.meshIntermediate Filament Proteins - metabolismen_HK
dc.subject.meshKeratin-20en_HK
dc.subject.meshKeratin-7en_HK
dc.subject.meshKeratins - metabolismen_HK
dc.subject.meshTumor Markers, Biological - metabolismen_HK
dc.subject.meshUrethral Neoplasms - etiology - metabolismen_HK
dc.subject.meshUrethritis - complicationsen_HK
dc.titleFemale urethral adenocarcinoma arising from urethritis glandularisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0090-8258&volume=79&spage=511&epage=514&date=2000&atitle=Female+urethral+adenocarcinoma+arising+from+urethritis+glandularisen_HK
dc.identifier.emailNgaYin Cheung, A:anycheun@hkucc.hku.hken_HK
dc.identifier.emailYuenSheung Ngan, H:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityNgaYin Cheung, A=rp00542en_HK
dc.identifier.authorityYuenSheung Ngan, H=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1006/gyno.2000.5968en_HK
dc.identifier.pmid11104631-
dc.identifier.scopuseid_2-s2.0-0033670528en_HK
dc.identifier.hkuros56308en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033670528&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume79en_HK
dc.identifier.issue3en_HK
dc.identifier.spage511en_HK
dc.identifier.epage514en_HK
dc.identifier.isiWOS:000165913700030-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChan, YM=7403676661en_HK
dc.identifier.scopusauthoridKaLeung Cheng, D=15738257500en_HK
dc.identifier.scopusauthoridNgaYin Cheung, A=54927484100en_HK
dc.identifier.scopusauthoridYuenSheung Ngan, H=34571944100en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK

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