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Article: The significance of the number of antral follicles prior to stimulation in predicting ovarian responses in an IVF programme

TitleThe significance of the number of antral follicles prior to stimulation in predicting ovarian responses in an IVF programme
Authors
KeywordsAntral follicles
IVF
Ovarian response
Ovarian volume
Issue Date2000
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
Human Reproduction, 2000, v. 15 n. 9, p. 1937-1942 How to Cite?
AbstractMultiple follicular development plays a major role in the successful outcome of IVF and embryo transfer treatment. Prediction of ovarian responses prior to stimulation is useful in counselling patients and helpful in tailoring the dosage of gonadotrophin to individual patients. The objective of this study was to compare age of women, body mass index (BMI), basal FSH concentration, volume of both ovaries and the number of antral follicles of both ovaries in predicting the number of oocytes obtained. A total of 128 consecutive women, who had no history of ovarian surgery, were non-smokers and undergoing the first cycle using a standard regimen of ovarian stimulation were examined. The total number of antral follicles achieved the best predictive value, followed by basal FSH, BMI and age of women. In those women with fewer antral follicles, a longer duration and higher dosage of human menopausal gonadotrophin were required but the number of eggs obtained was significantly less than for those with more antral follicles. Significantly more cycles were cancelled before egg collection in women with ≤6 antral follicles while more cycles of embryo transfer were postponed in order to reduce the risk of ovarian hyperstimulation syndrome in women with >9 antral follicles.
Persistent Identifierhttp://hdl.handle.net/10722/87433
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, EHYen_HK
dc.contributor.authorTang, OSen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:29:36Z-
dc.date.available2010-09-06T09:29:36Z-
dc.date.issued2000en_HK
dc.identifier.citationHuman Reproduction, 2000, v. 15 n. 9, p. 1937-1942en_HK
dc.identifier.issn0268-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87433-
dc.description.abstractMultiple follicular development plays a major role in the successful outcome of IVF and embryo transfer treatment. Prediction of ovarian responses prior to stimulation is useful in counselling patients and helpful in tailoring the dosage of gonadotrophin to individual patients. The objective of this study was to compare age of women, body mass index (BMI), basal FSH concentration, volume of both ovaries and the number of antral follicles of both ovaries in predicting the number of oocytes obtained. A total of 128 consecutive women, who had no history of ovarian surgery, were non-smokers and undergoing the first cycle using a standard regimen of ovarian stimulation were examined. The total number of antral follicles achieved the best predictive value, followed by basal FSH, BMI and age of women. In those women with fewer antral follicles, a longer duration and higher dosage of human menopausal gonadotrophin were required but the number of eggs obtained was significantly less than for those with more antral follicles. Significantly more cycles were cancelled before egg collection in women with ≤6 antral follicles while more cycles of embryo transfer were postponed in order to reduce the risk of ovarian hyperstimulation syndrome in women with >9 antral follicles.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/en_HK
dc.relation.ispartofHuman Reproductionen_HK
dc.rightsHuman Reproduction. Copyright © Oxford University Press.en_HK
dc.subjectAntral folliclesen_HK
dc.subjectIVFen_HK
dc.subjectOvarian responseen_HK
dc.subjectOvarian volumeen_HK
dc.titleThe significance of the number of antral follicles prior to stimulation in predicting ovarian responses in an IVF programmeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-1161&volume=15&issue=9&spage=1937&epage=1942&date=2000&atitle=The+significance+of+the+number+of+antral+follicles+prior+to+stimulation+in+predicting+ovarian+responses+in+an+IVF+programmeen_HK
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityNg, EHY=rp00426en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10966990-
dc.identifier.scopuseid_2-s2.0-0033816906en_HK
dc.identifier.hkuros56104en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033816906&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1937en_HK
dc.identifier.epage1942en_HK
dc.identifier.isiWOS:000089181600014-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNg, EHY=35238184300en_HK
dc.identifier.scopusauthoridTang, OS=36881248500en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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