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Article: Prognostic significance of tumour markers in endometrial cancer

TitlePrognostic significance of tumour markers in endometrial cancer
Authors
KeywordsCA125
CA15.3
CA19.9
Carcinoembryonic antigen
Endometrial cancer
Prognosis
Tissue polypeptide antigen
Issue Date1997
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/TBI
Citation
Tumor Biology, 1997, v. 18 n. 4, p. 241-249 How to Cite?
AbstractSerum cancer antigen (CA) 125, CA15.3, CA19.9, carcinoembryonic antigen and tissue polypeptide antigen were analyzed in 100 normal subjects, 47 patients with benign gynaecological diseases and 97 patients with endometrial cancer. The incidence of individual elevated turnout markers (>2SD) was 21.5- 30.9% in cancer patients. Elevations of CA125 and CA15.3 were significantly associated with poor prognostic clinical factors. Univariate anaylses showed that elevated CA125, CA15.3 and CA19.9 were significantly associated with shorter survival. In multivariate analyses, CA15.3 was highly significant and had a larger hazard ratio. In conclusion, CA15.3 is a useful marker for the prognosis of patients with endometrial cancer.
Persistent Identifierhttp://hdl.handle.net/10722/87401
ISSN
2015 Impact Factor: 2.926
2015 SCImago Journal Rankings: 0.989
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, SSTen_HK
dc.contributor.authorCheng, DKLen_HK
dc.contributor.authorNg, TYen_HK
dc.contributor.authorWong, LCen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-09-06T09:29:12Z-
dc.date.available2010-09-06T09:29:12Z-
dc.date.issued1997en_HK
dc.identifier.citationTumor Biology, 1997, v. 18 n. 4, p. 241-249en_HK
dc.identifier.issn1010-4283en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87401-
dc.description.abstractSerum cancer antigen (CA) 125, CA15.3, CA19.9, carcinoembryonic antigen and tissue polypeptide antigen were analyzed in 100 normal subjects, 47 patients with benign gynaecological diseases and 97 patients with endometrial cancer. The incidence of individual elevated turnout markers (>2SD) was 21.5- 30.9% in cancer patients. Elevations of CA125 and CA15.3 were significantly associated with poor prognostic clinical factors. Univariate anaylses showed that elevated CA125, CA15.3 and CA19.9 were significantly associated with shorter survival. In multivariate analyses, CA15.3 was highly significant and had a larger hazard ratio. In conclusion, CA15.3 is a useful marker for the prognosis of patients with endometrial cancer.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/TBIen_HK
dc.relation.ispartofTumor Biologyen_HK
dc.subjectCA125en_HK
dc.subjectCA15.3en_HK
dc.subjectCA19.9en_HK
dc.subjectCarcinoembryonic antigenen_HK
dc.subjectEndometrial canceren_HK
dc.subjectPrognosisen_HK
dc.subjectTissue polypeptide antigenen_HK
dc.titlePrognostic significance of tumour markers in endometrial canceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1010-4283&volume=18&spage=241&epage=249&date=1997&atitle=Prognostic+Significance+of+Tumour+Markers+in+Endometrial+Canceren_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9218009-
dc.identifier.scopuseid_2-s2.0-0030856662en_HK
dc.identifier.hkuros23877en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030856662&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume18en_HK
dc.identifier.issue4en_HK
dc.identifier.spage241en_HK
dc.identifier.epage249en_HK
dc.identifier.isiWOS:A1997XH06600006-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridLo, SST=15518872700en_HK
dc.identifier.scopusauthoridCheng, DKL=7402806161en_HK
dc.identifier.scopusauthoridNg, TY=7402229853en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

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