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Article: A randomized, double blind, placebo-controlled study to investigate the use of conscious sedation in conjunction with paracervical block for reducing pain in termination of first trimester pregnancy by suction evacuation

TitleA randomized, double blind, placebo-controlled study to investigate the use of conscious sedation in conjunction with paracervical block for reducing pain in termination of first trimester pregnancy by suction evacuation
Authors
KeywordsConscious sedation
Pain relief
Paracervical block
Suction evacuation
Termination of pregnancy
Issue Date2002
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
Human Reproduction, 2002, v. 17 n. 5, p. 1222-1225 How to Cite?
AbstractBackground: This study evaluated the role of conscious sedation in pain relief during termination of first trimester pregnancy by suction evacuation (SE) under local anaesthesia. Methods: A hundred women undergoing SE before 12 weeks gestation were randomized by computer using the sealed envelope method to receive placebo (saline) or conscious sedation (2 mg midazolam and 25 μg fentanyl) i.v. 5 min before cervical delatation. Paracervical block was given to all patients, 2 min later. Pain scores during and after SE, post-operative side-effects and satisfaction level were compared. Results: No statistically significant differences in pain scores were found between the two groups. Post-operative side-effects such as dizziness (P = 0.015) and drowsiness (P < 0.001) were significantly more severe in the conscious sedation group. However, patients in the conscious sedation group reported better satisfaction levels than the control group (P = 0.003). Conclusion: The use of conscious sedation significantly improved patient satisfaction during termination of first trimester pregnancy by SE under local anaesthesia, despite a lack of improvement in pain relief and the presence of increased severe dizziness/drowsiness in the post-operative period.
Persistent Identifierhttp://hdl.handle.net/10722/87387
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, CYGen_HK
dc.contributor.authorNg, EHYen_HK
dc.contributor.authorNgai, SWen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:29:01Z-
dc.date.available2010-09-06T09:29:01Z-
dc.date.issued2002en_HK
dc.identifier.citationHuman Reproduction, 2002, v. 17 n. 5, p. 1222-1225en_HK
dc.identifier.issn0268-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87387-
dc.description.abstractBackground: This study evaluated the role of conscious sedation in pain relief during termination of first trimester pregnancy by suction evacuation (SE) under local anaesthesia. Methods: A hundred women undergoing SE before 12 weeks gestation were randomized by computer using the sealed envelope method to receive placebo (saline) or conscious sedation (2 mg midazolam and 25 μg fentanyl) i.v. 5 min before cervical delatation. Paracervical block was given to all patients, 2 min later. Pain scores during and after SE, post-operative side-effects and satisfaction level were compared. Results: No statistically significant differences in pain scores were found between the two groups. Post-operative side-effects such as dizziness (P = 0.015) and drowsiness (P < 0.001) were significantly more severe in the conscious sedation group. However, patients in the conscious sedation group reported better satisfaction levels than the control group (P = 0.003). Conclusion: The use of conscious sedation significantly improved patient satisfaction during termination of first trimester pregnancy by SE under local anaesthesia, despite a lack of improvement in pain relief and the presence of increased severe dizziness/drowsiness in the post-operative period.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/en_HK
dc.relation.ispartofHuman Reproductionen_HK
dc.rightsHuman Reproduction. Copyright © Oxford University Press.en_HK
dc.subjectConscious sedationen_HK
dc.subjectPain reliefen_HK
dc.subjectParacervical blocken_HK
dc.subjectSuction evacuationen_HK
dc.subjectTermination of pregnancyen_HK
dc.titleA randomized, double blind, placebo-controlled study to investigate the use of conscious sedation in conjunction with paracervical block for reducing pain in termination of first trimester pregnancy by suction evacuationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-1161&volume=17&issue=5&spage=1222&epage=1225&date=2002&atitle=A+randomized,+double+blind,+placebo-controlled+study+to+investigate+the+use+of+conscious+sedation+in+conjunction+with+paracervical+block+for+reducing+pain+in+termination+of+first+trimester+pregnancy+by+suction+evacuationen_HK
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityNg, EHY=rp00426en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid11980742-
dc.identifier.scopuseid_2-s2.0-0036107793en_HK
dc.identifier.hkuros66984en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036107793&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue5en_HK
dc.identifier.spage1222en_HK
dc.identifier.epage1225en_HK
dc.identifier.isiWOS:000175387700016-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, CYG=9234680400en_HK
dc.identifier.scopusauthoridNg, EHY=35238184300en_HK
dc.identifier.scopusauthoridNgai, SW=7006074214en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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