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Article: A randomised comparison of side effects and patient inconvenience of two vaginal progesterone formulations used for luteal support in in vitro fertilisation cycles

TitleA randomised comparison of side effects and patient inconvenience of two vaginal progesterone formulations used for luteal support in in vitro fertilisation cycles
Authors
KeywordsCrinone
Cyclogest
Progesterone
Issue Date2003
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejogrb
Citation
European Journal Of Obstetrics Gynecology And Reproductive Biology, 2003, v. 111 n. 1, p. 50-54 How to Cite?
AbstractObjective: To compare side effects and patient inconvenience of two vaginal progesterone (P) formulations for luteal support in in vitro fertilisation cycles. Study design: Sixty infertile patients at risk of developing ovarian hyperstimulation syndrome were randomised to receive either Cyclogest vaginal suppositories 400mg twice daily or Crinone 8% vaginal gel once daily for 14 days as the luteal support. On Day 6 and Day 16 after embryo transfer, they rated side effects and patient inconvenience into four grades: none, mild, moderate and severe by completing a questionnaire. Results: Perineal irritation was reported by about 20% of patients in each group. Significantly more patients using Cyclogest suppositories graded inconvenience of administration, leaking out and interference with coitus as moderate or severe. Conclusion: There was no difference in perineal irritation after Cyclogest suppositories or Crinone 8% gel although significantly more patients found inconvenience of administration, leaking out and interference with coitus after Cyclogest. © 2003 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/87230
ISSN
2015 Impact Factor: 1.662
2015 SCImago Journal Rankings: 0.808
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, EHYen_HK
dc.contributor.authorMiao, Ben_HK
dc.contributor.authorCheung, Wen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:27:00Z-
dc.date.available2010-09-06T09:27:00Z-
dc.date.issued2003en_HK
dc.identifier.citationEuropean Journal Of Obstetrics Gynecology And Reproductive Biology, 2003, v. 111 n. 1, p. 50-54en_HK
dc.identifier.issn0301-2115en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87230-
dc.description.abstractObjective: To compare side effects and patient inconvenience of two vaginal progesterone (P) formulations for luteal support in in vitro fertilisation cycles. Study design: Sixty infertile patients at risk of developing ovarian hyperstimulation syndrome were randomised to receive either Cyclogest vaginal suppositories 400mg twice daily or Crinone 8% vaginal gel once daily for 14 days as the luteal support. On Day 6 and Day 16 after embryo transfer, they rated side effects and patient inconvenience into four grades: none, mild, moderate and severe by completing a questionnaire. Results: Perineal irritation was reported by about 20% of patients in each group. Significantly more patients using Cyclogest suppositories graded inconvenience of administration, leaking out and interference with coitus as moderate or severe. Conclusion: There was no difference in perineal irritation after Cyclogest suppositories or Crinone 8% gel although significantly more patients found inconvenience of administration, leaking out and interference with coitus after Cyclogest. © 2003 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejogrben_HK
dc.relation.ispartofEuropean Journal of Obstetrics Gynecology and Reproductive Biologyen_HK
dc.rightsEuropean Journal of Obstetrics & Gynecology and Reproductive Biology. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectCrinoneen_HK
dc.subjectCyclogesten_HK
dc.subjectProgesteroneen_HK
dc.titleA randomised comparison of side effects and patient inconvenience of two vaginal progesterone formulations used for luteal support in in vitro fertilisation cyclesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0301-2115&volume=111&spage=50&epage=54&date=2003&atitle=A+randomised+comparison+of+side+effects+and+patient+inconvenience+of+two+vaginal+progesterone+formulations+used+for+luteal+support+in+in+vitro+fertilisation+cyclesen_HK
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityNg, EHY=rp00426en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0301-2115(03)00156-8en_HK
dc.identifier.pmid14557011-
dc.identifier.scopuseid_2-s2.0-0141992764en_HK
dc.identifier.hkuros87475en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0141992764&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume111en_HK
dc.identifier.issue1en_HK
dc.identifier.spage50en_HK
dc.identifier.epage54en_HK
dc.identifier.isiWOS:000186099600010-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridNg, EHY=35238184300en_HK
dc.identifier.scopusauthoridMiao, B=7005706356en_HK
dc.identifier.scopusauthoridCheung, W=7202743060en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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