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Article: Multivariate analysis of factors affecting survival in pelvic exenteration

TitleMultivariate analysis of factors affecting survival in pelvic exenteration
Authors
Keywordsmultivariate analysis
pelvic exenteration
Issue Date1994
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ijgc.net/
Citation
International Journal Of Gynecological Cancer, 1994, v. 4 n. 6, p. 361-370 How to Cite?
AbstractOf 153 patients with primary or recurrent pelvic malignancy referred for consideration of exenteration, only 40.6% (62 patients) were found to be suitable for exenteration after full assessment. Thirty percent (46 patients) were found to be inoperable on examination under anesthesia. Of the remaining 107 patients, 33% (35 patients) were found to be inoperable at laparotomy, 9% (10 patients) underwent radical hysterectomy and 58% (62 patients) had an exenterative procedure. One patient had no active disease found on final histologic review of the exenteration surgical specimen and was excluded, as the aim of this study was to look at the prognostic factors affecting survival. There remained 61 patients in the exenteration group who were analyzed. The 2-year survival rate was less than 2% for patients with inoperable disease, 48% for patients who underwent radical hysterectomy and 54.1% for patients who underwent exenteration. The 5-year survival rate for all patients undergoing exenteration for pelvic malignancies was 44% and that for cervical cancer only was 52%. Multivariate analysis of patients who had undergone exenteration showed four significantly poor prognostic factors influencing survival. They were: (a) aged older than 69 years, (b) recurrence of the tumor within 3 years, (c) persistent recurrence, and (d) positive resection margins.
Persistent Identifierhttp://hdl.handle.net/10722/87160
ISSN
2015 Impact Factor: 2.116
2015 SCImago Journal Rankings: 0.830
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShepherd, JHen_HK
dc.contributor.authorNgan, HYSen_HK
dc.contributor.authorNeven, Pen_HK
dc.contributor.authorFryatt, Ien_HK
dc.contributor.authorWoodhouse, CRJen_HK
dc.contributor.authorHendry, WFen_HK
dc.date.accessioned2010-09-06T09:26:06Z-
dc.date.available2010-09-06T09:26:06Z-
dc.date.issued1994en_HK
dc.identifier.citationInternational Journal Of Gynecological Cancer, 1994, v. 4 n. 6, p. 361-370en_HK
dc.identifier.issn1048-891Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/87160-
dc.description.abstractOf 153 patients with primary or recurrent pelvic malignancy referred for consideration of exenteration, only 40.6% (62 patients) were found to be suitable for exenteration after full assessment. Thirty percent (46 patients) were found to be inoperable on examination under anesthesia. Of the remaining 107 patients, 33% (35 patients) were found to be inoperable at laparotomy, 9% (10 patients) underwent radical hysterectomy and 58% (62 patients) had an exenterative procedure. One patient had no active disease found on final histologic review of the exenteration surgical specimen and was excluded, as the aim of this study was to look at the prognostic factors affecting survival. There remained 61 patients in the exenteration group who were analyzed. The 2-year survival rate was less than 2% for patients with inoperable disease, 48% for patients who underwent radical hysterectomy and 54.1% for patients who underwent exenteration. The 5-year survival rate for all patients undergoing exenteration for pelvic malignancies was 44% and that for cervical cancer only was 52%. Multivariate analysis of patients who had undergone exenteration showed four significantly poor prognostic factors influencing survival. They were: (a) aged older than 69 years, (b) recurrence of the tumor within 3 years, (c) persistent recurrence, and (d) positive resection margins.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ijgc.net/en_HK
dc.relation.ispartofInternational Journal of Gynecological Canceren_HK
dc.subjectmultivariate analysisen_HK
dc.subjectpelvic exenterationen_HK
dc.titleMultivariate analysis of factors affecting survival in pelvic exenterationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1048-891X&volume=4&spage=361&epage=370&date=1994&atitle=Multivariate+analysis+of+factors+affecting+survival+in+pelvic+exenterationen_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1525-1438.1994.04060361.xen_HK
dc.identifier.scopuseid_2-s2.0-0028639250en_HK
dc.identifier.hkuros3123en_HK
dc.identifier.volume4en_HK
dc.identifier.issue6en_HK
dc.identifier.spage361en_HK
dc.identifier.epage370en_HK
dc.identifier.isiWOS:A1994PQ41100001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridShepherd, JH=7401741987en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK
dc.identifier.scopusauthoridNeven, P=7005856240en_HK
dc.identifier.scopusauthoridFryatt, I=6603634530en_HK
dc.identifier.scopusauthoridWoodhouse, CRJ=7101819249en_HK
dc.identifier.scopusauthoridHendry, WF=14823702700en_HK

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