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Article: Assisted reproduction technology in Queen Mary Hospital: Ten years' experience

TitleAssisted reproduction technology in Queen Mary Hospital: Ten years' experience
Authors
Issue Date1997
PublisherChinese Medical Association. The Journal's web site is located at http://www.cmj.org/
Citation
Chinese Medical Journal, 1997, v. 110 n. 6, p. 444-447 How to Cite?
AbstractPurpose To review the experience of an assisted reproduction program. Data sources Department of Obstetrics and Gynaecology, University of Hong Kong. Study selection Assisted reproduction in a tertiary referral centre. Data extraction Results of assisted reproduction from 1986-1996. Results In the past ten years, 1561 treatment cycles of in vitro fertilization and embryo transfer (IVF), 257 of gamete intrafallopian transfer (GIFT) and 217 of pronuclear stage tubal transfer (PROST) were initiated. The clinical pregnancy rates per cycle started were 10.8% for IVF, 16.3% for GIFT and 15.7% for PROST. As a result of improvement in ovarian stimulation and embryo culture, the success rate of the program increased in recent years. The pregnancy rate of IVF per embryo transfer was 20.2% in 1995. Embryo cryopreservation program was started in 1992. Since then, 664 cycles of replacement of frozen-thawed embryos were completed with a pregnancy rate of 14.6% per cycle. One hundred and forty-three cycles of assisted fertilization using various techniques, namely partial zona dissection, subzonal sperm injection and intracytoplasmic sperm injection, were performed. The success rate was the highest for the latter technique with a pregnancy rate of 14% per transfer cycle. A prospective randomized control trial on the use of coculture in assisted reproduction had also been done. Results indicated that coculture of embryos with human oviductal cells improved the implantation rate of the embryos. Conclusion Various technique development have been made to improve the success rate of assisted reproduction as well as the quality of treatment of infertility.
Persistent Identifierhttp://hdl.handle.net/10722/87149
ISSN
2015 Impact Factor: 0.957
2015 SCImago Journal Rankings: 0.428
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYeung, SBen_HK
dc.contributor.authorLau, YLen_HK
dc.contributor.authorSo, WKen_HK
dc.contributor.authorNg, HYen_HK
dc.contributor.authorChan, THen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:25:57Z-
dc.date.available2010-09-06T09:25:57Z-
dc.date.issued1997en_HK
dc.identifier.citationChinese Medical Journal, 1997, v. 110 n. 6, p. 444-447en_HK
dc.identifier.issn0366-6999en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87149-
dc.description.abstractPurpose To review the experience of an assisted reproduction program. Data sources Department of Obstetrics and Gynaecology, University of Hong Kong. Study selection Assisted reproduction in a tertiary referral centre. Data extraction Results of assisted reproduction from 1986-1996. Results In the past ten years, 1561 treatment cycles of in vitro fertilization and embryo transfer (IVF), 257 of gamete intrafallopian transfer (GIFT) and 217 of pronuclear stage tubal transfer (PROST) were initiated. The clinical pregnancy rates per cycle started were 10.8% for IVF, 16.3% for GIFT and 15.7% for PROST. As a result of improvement in ovarian stimulation and embryo culture, the success rate of the program increased in recent years. The pregnancy rate of IVF per embryo transfer was 20.2% in 1995. Embryo cryopreservation program was started in 1992. Since then, 664 cycles of replacement of frozen-thawed embryos were completed with a pregnancy rate of 14.6% per cycle. One hundred and forty-three cycles of assisted fertilization using various techniques, namely partial zona dissection, subzonal sperm injection and intracytoplasmic sperm injection, were performed. The success rate was the highest for the latter technique with a pregnancy rate of 14% per transfer cycle. A prospective randomized control trial on the use of coculture in assisted reproduction had also been done. Results indicated that coculture of embryos with human oviductal cells improved the implantation rate of the embryos. Conclusion Various technique development have been made to improve the success rate of assisted reproduction as well as the quality of treatment of infertility.en_HK
dc.languageengen_HK
dc.publisherChinese Medical Association. The Journal's web site is located at http://www.cmj.org/en_HK
dc.relation.ispartofChinese Medical Journalen_HK
dc.titleAssisted reproduction technology in Queen Mary Hospital: Ten years' experienceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0366-6999&volume=110&issue=6&spage=444&epage=447&date=1997&atitle=Assisted+reproduction+technology+in+Queen+Mary+Hospital+:+ten+years%27+experienceen_HK
dc.identifier.emailYeung, SB:wsbyeung@hkucc.hku.hken_HK
dc.identifier.emailNg, HY:nghye@hkucc.hku.hken_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityYeung, SB=rp00331en_HK
dc.identifier.authorityNg, HY=rp00426en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid9594245-
dc.identifier.scopuseid_2-s2.0-0031152190en_HK
dc.identifier.hkuros23009en_HK
dc.identifier.hkuros33347-
dc.identifier.hkuros27312-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031152190&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume110en_HK
dc.identifier.issue6en_HK
dc.identifier.spage444en_HK
dc.identifier.epage447en_HK
dc.identifier.isiWOS:A1997XM38400009-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridYeung, SB=7102370745en_HK
dc.identifier.scopusauthoridLau, YL=7103086093en_HK
dc.identifier.scopusauthoridSo, WK=36849240300en_HK
dc.identifier.scopusauthoridNg, HY=35238184300en_HK
dc.identifier.scopusauthoridChan, TH=7402687869en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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