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Article: Conservative treatment of low grade squamous intraepithelial lesions (LSIL) of the cervix

TitleConservative treatment of low grade squamous intraepithelial lesions (LSIL) of the cervix
Authors
KeywordsColposcopy
Conservative treatment
Cytology
Histology
Low grade squamous intraepithelial lesions (LSIL)
Issue Date1998
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijgo
Citation
International Journal Of Gynecology And Obstetrics, 1998, v. 60 n. 1, p. 35-40 How to Cite?
AbstractObjective: To assess the accuracy of the cervical smear and colposcopy in diagnosing low grade squamous intraepithelial lesions (LSIL), and the natural history of LSIL. Method: The cytological, colposcopic and histological findings of 145 patients with a smear diagnosis of LSIL were compared, and the final outcome studied. Results: The diagnosis of LSIL either by cytology alone or in combination with colposcopy was associated with a rate of overdiagnosis of 11.7% and 6.9%, respectively, and a rate of underdiagnosis of 31.0% and 26.2%, respectively. Spontaneous regression of lesions occurred in 81.1% of patients with proven LSIL, with regression within 24 months in 4/5 of cases. Conclusions: The degree of dysplasia shown in the cervical smear correlated poorly with histology. All patients with cervical smear showing LSIL should have colposcopy and colposcopic-directed biopsy to exclude the presence of more advanced lesions. In the absence of some serious lesions, it is then acceptable to observe the patient for 24 months before adopting definite treatment, as spontaneous regression is common.
Persistent Identifierhttp://hdl.handle.net/10722/87135
ISSN
2015 Impact Factor: 1.674
2015 SCImago Journal Rankings: 1.544
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLee, SSNen_HK
dc.contributor.authorCollins, RJen_HK
dc.contributor.authorPun, TCen_HK
dc.contributor.authorCheng, DKLen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-09-06T09:25:47Z-
dc.date.available2010-09-06T09:25:47Z-
dc.date.issued1998en_HK
dc.identifier.citationInternational Journal Of Gynecology And Obstetrics, 1998, v. 60 n. 1, p. 35-40en_HK
dc.identifier.issn0020-7292en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87135-
dc.description.abstractObjective: To assess the accuracy of the cervical smear and colposcopy in diagnosing low grade squamous intraepithelial lesions (LSIL), and the natural history of LSIL. Method: The cytological, colposcopic and histological findings of 145 patients with a smear diagnosis of LSIL were compared, and the final outcome studied. Results: The diagnosis of LSIL either by cytology alone or in combination with colposcopy was associated with a rate of overdiagnosis of 11.7% and 6.9%, respectively, and a rate of underdiagnosis of 31.0% and 26.2%, respectively. Spontaneous regression of lesions occurred in 81.1% of patients with proven LSIL, with regression within 24 months in 4/5 of cases. Conclusions: The degree of dysplasia shown in the cervical smear correlated poorly with histology. All patients with cervical smear showing LSIL should have colposcopy and colposcopic-directed biopsy to exclude the presence of more advanced lesions. In the absence of some serious lesions, it is then acceptable to observe the patient for 24 months before adopting definite treatment, as spontaneous regression is common.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijgoen_HK
dc.relation.ispartofInternational Journal of Gynecology and Obstetricsen_HK
dc.rightsInternational Journal of Gynecology & Obstetrics. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectColposcopyen_HK
dc.subjectConservative treatmenten_HK
dc.subjectCytologyen_HK
dc.subjectHistologyen_HK
dc.subjectLow grade squamous intraepithelial lesions (LSIL)en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshBiopsyen_HK
dc.subject.meshCervical Intraepithelial Neoplasia - pathology - therapyen_HK
dc.subject.meshColposcopyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshRemission, Spontaneousen_HK
dc.subject.meshReproducibility of Resultsen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshSensitivity and Specificityen_HK
dc.subject.meshUterine Cervical Dysplasia - pathology - therapyen_HK
dc.subject.meshUterine Cervical Neoplasms - pathology - therapyen_HK
dc.subject.meshVaginal Smearsen_HK
dc.titleConservative treatment of low grade squamous intraepithelial lesions (LSIL) of the cervixen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0020-7292&volume=60&spage=35&epage=40&date=1997&atitle=Conservative+treatment+of+low+grade+squamous+intraepithelial+lesions+(LSIL)+of+the+cervixen_HK
dc.identifier.emailCollins, RJ:rcollins@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityCollins, RJ=rp00251en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0020-7292(97)00219-1en_HK
dc.identifier.pmid9506412-
dc.identifier.scopuseid_2-s2.0-0031983714en_HK
dc.identifier.hkuros31652en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031983714&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume60en_HK
dc.identifier.issue1en_HK
dc.identifier.spage35en_HK
dc.identifier.epage40en_HK
dc.identifier.isiWOS:000071930400006-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridLee, SSN=27169619100en_HK
dc.identifier.scopusauthoridCollins, RJ=7403350455en_HK
dc.identifier.scopusauthoridPun, TC=7005509306en_HK
dc.identifier.scopusauthoridCheng, DKL=7402806161en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

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