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Article: Hepatic arteriogram for gestational trophoblastic tumor: Is it useful?

TitleHepatic arteriogram for gestational trophoblastic tumor: Is it useful?
Authors
Issue Date2005
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/07357907.asp
Citation
Cancer Investigation, 2005, v. 23 n. 8, p. 677-682 How to Cite?
AbstractThe presence of liver metastasis will be staged as IV in the FIGO 1992 Gestational Trophoblastic Tumor (GTT) staging. This study was to determine the role of hepatic arteriogram (HAG) in the management of GTT. It is a retrospective analysis of 309 patients treated from 1981 to 2001. Patients were restaged according to the FIGO 1992 classification with or without taking into account the HAG result. Outcome measures including mortality, drug resistance and recurrence of disease, as well as treatment with and without the HAG result were compared. Eighty-one (26.2 percent) patients had HAG and 11 (3.6 percent) also had ultrasound (USG) features of liver metastasis. Interval between diagnosis and treatment were significantly different between USG and HAG positive groups (Mann-Whitney U test, P < 0.05). Seventeen (5.5 percent) of the 309 patients died of the disease and 7 (41.2 percent) of them had liver metastasis. Three (27.3 percent) of the 11 patients who had USG features of liver metastasis died of the disease; mortality is significantly higher than those without USG features of metastasis (Chi-square test, P < 0.05). Patients classified as medium to high risk with or without taking HAG as a feature of liver metastasis were associated with higher mortality and recurrent rate (Chi-square test, P < 0.05). On the other hand, the chance of drug resistance was higher in the medium to high risk group after reclassifying all HAG positive patients as negative for liver metastasis (Chi-square test, P < 0.05). HAG evidence of liver metastasis did not correlate with patient mortality. HAG was not an appropriate investigation in the management of GTT. Copyright © Taylor & Francis LLC.
Persistent Identifierhttp://hdl.handle.net/10722/87049
ISSN
2015 Impact Factor: 2.231
2015 SCImago Journal Rankings: 0.991
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTam, KFen_HK
dc.contributor.authorChau, MTen_HK
dc.contributor.authorChan, YMen_HK
dc.contributor.authorNg, TYen_HK
dc.contributor.authorWong, LCen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-09-06T09:24:39Z-
dc.date.available2010-09-06T09:24:39Z-
dc.date.issued2005en_HK
dc.identifier.citationCancer Investigation, 2005, v. 23 n. 8, p. 677-682en_HK
dc.identifier.issn0735-7907en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87049-
dc.description.abstractThe presence of liver metastasis will be staged as IV in the FIGO 1992 Gestational Trophoblastic Tumor (GTT) staging. This study was to determine the role of hepatic arteriogram (HAG) in the management of GTT. It is a retrospective analysis of 309 patients treated from 1981 to 2001. Patients were restaged according to the FIGO 1992 classification with or without taking into account the HAG result. Outcome measures including mortality, drug resistance and recurrence of disease, as well as treatment with and without the HAG result were compared. Eighty-one (26.2 percent) patients had HAG and 11 (3.6 percent) also had ultrasound (USG) features of liver metastasis. Interval between diagnosis and treatment were significantly different between USG and HAG positive groups (Mann-Whitney U test, P < 0.05). Seventeen (5.5 percent) of the 309 patients died of the disease and 7 (41.2 percent) of them had liver metastasis. Three (27.3 percent) of the 11 patients who had USG features of liver metastasis died of the disease; mortality is significantly higher than those without USG features of metastasis (Chi-square test, P < 0.05). Patients classified as medium to high risk with or without taking HAG as a feature of liver metastasis were associated with higher mortality and recurrent rate (Chi-square test, P < 0.05). On the other hand, the chance of drug resistance was higher in the medium to high risk group after reclassifying all HAG positive patients as negative for liver metastasis (Chi-square test, P < 0.05). HAG evidence of liver metastasis did not correlate with patient mortality. HAG was not an appropriate investigation in the management of GTT. Copyright © Taylor & Francis LLC.en_HK
dc.languageengen_HK
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/07357907.aspen_HK
dc.relation.ispartofCancer Investigationen_HK
dc.rightsCancer Investigation. Copyright © Informa Healthcare.en_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAngiographyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGestational Trophoblastic Disease - diagnosis - pathology - radiography - therapyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLiver Neoplasms - blood supply - radiography - secondary - therapyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNeoplasm Stagingen_HK
dc.subject.meshPregnancyen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleHepatic arteriogram for gestational trophoblastic tumor: Is it useful?en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0735-7907&volume=23&spage=677&epage=682&date=2005&atitle=Hepatic+arteriogram+for+gestational+trophoblastic+tumor:+Is+it+useful?en_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1080/07357900500359968en_HK
dc.identifier.pmid16377586-
dc.identifier.scopuseid_2-s2.0-29944445476en_HK
dc.identifier.hkuros118948en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-29944445476&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue8en_HK
dc.identifier.spage677en_HK
dc.identifier.epage682en_HK
dc.identifier.isiWOS:000234248900005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTam, KF=35622901400en_HK
dc.identifier.scopusauthoridChau, MT=7006073758en_HK
dc.identifier.scopusauthoridChan, YM=7403676661en_HK
dc.identifier.scopusauthoridNg, TY=7402229853en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

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