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Article: The roles of multimodality treatment and lymphadenectomy in the management of esophageal cancer

TitleThe roles of multimodality treatment and lymphadenectomy in the management of esophageal cancer
Authors
Issue Date1997
PublisherZhonghua Yixuehui. The Journal's web site is located at http://www.cmj.org/
Citation
Chinese Medical Journal, 1997, v. 110 n. 11, p. 819-825 How to Cite?
AbstractPurpose: To review the current status of multimodality treatment and lymphadenectomy in the management of esophageal cancer. Data sources: Literature review. Study selection: Multimodality treatment and lymphadenectomy in esophageal cancer. Data extraction: Multimodality treatment and lymphadenectomy in esophageal cancer. Data extraction: Results in research papers published selected by literature search. Results: Numerous studies have been carried out attempting to define the roles of various neoadjuvant or adjuvant regimens in the treatment of esophageal cancer. These included the use of radiotherapy or chemotherapy alone or in different combinations, with or without surgical resection. Randomized trials have failed to show significant improvement compared with surgical resection alone, although downstaging of disease and benefits on subgroups of patients could be demonstrated. Whether the extent of resection can influence outcome was tested by varying the surgical approach, and by increasing the extent of lymphadenectomy. Although indirect evidence exists suggesting more extensive resection may improve long term prognosis, definitive proof is lacking. Conclusions: More well organized randomized controlled trials are needed to further elucidate the roles of these approaches in the treatment of esophageal cancer.
Persistent Identifierhttp://hdl.handle.net/10722/83138
ISSN
2015 Impact Factor: 0.957
2015 SCImago Journal Rankings: 0.428
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, Sen_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2010-09-06T08:37:27Z-
dc.date.available2010-09-06T08:37:27Z-
dc.date.issued1997en_HK
dc.identifier.citationChinese Medical Journal, 1997, v. 110 n. 11, p. 819-825en_HK
dc.identifier.issn0366-6999en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83138-
dc.description.abstractPurpose: To review the current status of multimodality treatment and lymphadenectomy in the management of esophageal cancer. Data sources: Literature review. Study selection: Multimodality treatment and lymphadenectomy in esophageal cancer. Data extraction: Multimodality treatment and lymphadenectomy in esophageal cancer. Data extraction: Results in research papers published selected by literature search. Results: Numerous studies have been carried out attempting to define the roles of various neoadjuvant or adjuvant regimens in the treatment of esophageal cancer. These included the use of radiotherapy or chemotherapy alone or in different combinations, with or without surgical resection. Randomized trials have failed to show significant improvement compared with surgical resection alone, although downstaging of disease and benefits on subgroups of patients could be demonstrated. Whether the extent of resection can influence outcome was tested by varying the surgical approach, and by increasing the extent of lymphadenectomy. Although indirect evidence exists suggesting more extensive resection may improve long term prognosis, definitive proof is lacking. Conclusions: More well organized randomized controlled trials are needed to further elucidate the roles of these approaches in the treatment of esophageal cancer.en_HK
dc.languageengen_HK
dc.publisherZhonghua Yixuehui. The Journal's web site is located at http://www.cmj.org/en_HK
dc.relation.ispartofChinese Medical Journalen_HK
dc.titleThe roles of multimodality treatment and lymphadenectomy in the management of esophageal canceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0366-6999&volume=110&spage=819&epage=825&date=1997&atitle=The+roles+of+multimodality+treatment+and+lymphadenectomy+in+the+management+of+esophageal+canceren_HK
dc.identifier.emailLaw, S: slaw@hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityLaw, S=rp00437en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9772410en_HK
dc.identifier.scopuseid_2-s2.0-0030687982en_HK
dc.identifier.hkuros28770en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030687982&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume110en_HK
dc.identifier.issue11en_HK
dc.identifier.spage819en_HK
dc.identifier.epage825en_HK
dc.identifier.isiWOS:A1997YH67300001-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridLaw, S=7202241293en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK

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