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Article: Anti-psychotics adherence among out-patients with schizophrenia in Hong Kong

TitleAnti-psychotics adherence among out-patients with schizophrenia in Hong Kong
Authors
KeywordsCompliance
Medication adherence
Schizophrenia
Issue Date2006
PublisherKeio Gijuku Daigaku, Igakubu. The Journal's web site is located at http://www.kjm.keio.ac.jp
Citation
Keio Journal Of Medicine, 2006, v. 55 n. 1, p. 9-14 How to Cite?
AbstractObjective: Adherence to antipsychotic treatment is an important aspect of long term management of schizophrenia and other related psychotic disorders. The evaluation of adherence is often difficult in clinical settings. This study compared patients self-reports and clinician judgment of adherence behavior and explored their relationship with attitudes toward taking medication. Methods: Clinician rated questionnaire and matching patient self rated questionnaires were administered to 508 consecutive outpatients and their clinicians in four hospital clinic sites in Hong Kong. Items in the questionnaires address adherence behaviors as well as attitudes toward medication. In addition, clinicians also estimate the presence of factors unfavorable to adherence such as substance abuse, cognitive impairments etc. Results: Non-adherence was reported in at least 26% of patients. Clinician's detection of non-adherence behaviors achieved relative high specificity (0.84) but has low sensitivity (0.33). A logistic regression analysis on patients' decision to stop medication revealed that significant predictors include patients' reported lack of perception from the benefits of medication, patients' reported negative feelings associated with regular medication and younger age. Conclusion: Non-adherence is a widespread phenomenon affecting a significant proportion of outpatients under treatment. Clinicians have relatively low sensitivity in detecting which patients are non-adherent. Non-adherence behavior is predicted by level of awareness of illness, perceived benefits of medication, negative feelings toward medication and age.
Persistent Identifierhttp://hdl.handle.net/10722/81606
ISSN
2015 SCImago Journal Rankings: 0.777
References

 

DC FieldValueLanguage
dc.contributor.authorHui, CLMen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorKan, CSen_HK
dc.contributor.authorYip, KCen_HK
dc.contributor.authorLaw, CWen_HK
dc.contributor.authorChiu, CPYen_HK
dc.date.accessioned2010-09-06T08:19:49Z-
dc.date.available2010-09-06T08:19:49Z-
dc.date.issued2006en_HK
dc.identifier.citationKeio Journal Of Medicine, 2006, v. 55 n. 1, p. 9-14en_HK
dc.identifier.issn0022-9717en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81606-
dc.description.abstractObjective: Adherence to antipsychotic treatment is an important aspect of long term management of schizophrenia and other related psychotic disorders. The evaluation of adherence is often difficult in clinical settings. This study compared patients self-reports and clinician judgment of adherence behavior and explored their relationship with attitudes toward taking medication. Methods: Clinician rated questionnaire and matching patient self rated questionnaires were administered to 508 consecutive outpatients and their clinicians in four hospital clinic sites in Hong Kong. Items in the questionnaires address adherence behaviors as well as attitudes toward medication. In addition, clinicians also estimate the presence of factors unfavorable to adherence such as substance abuse, cognitive impairments etc. Results: Non-adherence was reported in at least 26% of patients. Clinician's detection of non-adherence behaviors achieved relative high specificity (0.84) but has low sensitivity (0.33). A logistic regression analysis on patients' decision to stop medication revealed that significant predictors include patients' reported lack of perception from the benefits of medication, patients' reported negative feelings associated with regular medication and younger age. Conclusion: Non-adherence is a widespread phenomenon affecting a significant proportion of outpatients under treatment. Clinicians have relatively low sensitivity in detecting which patients are non-adherent. Non-adherence behavior is predicted by level of awareness of illness, perceived benefits of medication, negative feelings toward medication and age.en_HK
dc.languageengen_HK
dc.publisherKeio Gijuku Daigaku, Igakubu. The Journal's web site is located at http://www.kjm.keio.ac.jpen_HK
dc.relation.ispartofKeio Journal of Medicineen_HK
dc.subjectComplianceen_HK
dc.subjectMedication adherenceen_HK
dc.subjectSchizophreniaen_HK
dc.titleAnti-psychotics adherence among out-patients with schizophrenia in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-9717&volume=55 no 1&spage=9&epage=14&date=2006&atitle=Anti-psychotics+adherence+among+out-patients+with+schizophrenia+in+Hong+Kongen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.emailChiu, CPY: chiupyc@hku.hken_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.identifier.authorityChiu, CPY=rp00291en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.2302/kjm.55.9en_HK
dc.identifier.pmid16636644-
dc.identifier.scopuseid_2-s2.0-33646577190en_HK
dc.identifier.hkuros115295en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33646577190&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume55en_HK
dc.identifier.issue1en_HK
dc.identifier.spage9en_HK
dc.identifier.epage14en_HK
dc.publisher.placeJapanen_HK
dc.identifier.scopusauthoridHui, CLM=35734149500en_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridKan, CS=7102156197en_HK
dc.identifier.scopusauthoridYip, KC=28168097100en_HK
dc.identifier.scopusauthoridLaw, CW=8627115600en_HK
dc.identifier.scopusauthoridChiu, CPY=8627115700en_HK

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