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Article: Cerebral infarcts complicating tuberculous meningitis

TitleCerebral infarcts complicating tuberculous meningitis
Authors
Issue Date2005
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/CED
Citation
Cerebrovascular Diseases, 2005, v. 19 n. 6, p. 391-395 How to Cite?
AbstractCerebral infarction (CI) is a serious complication of tuberculous meningitis (TBM). It can be asymptomatic or symptomatic, causing stroke. We studied 40 TBM patients. All had initial CT brain scan, CT/MRI brain scan 3 months later and urgent CT brain scan for deterioration. CI was classified into lacunar infarction (LI) or large artery infarction (LAI). Twelve (30%) had CI, in 9 (23%) it was symptomatic and in 3 (8%) silent. Seven (58%) had LAI ± LI. Eight (67%) had multiple CI. Two died from brainstem CI and 6 were dependent at 1 year. Patients with LAI might develop posterior circulation CI more frequently than those with LI only. CI is a common complication of TBM locally, with LAI and multiple CI being common. Two thirds of TBM patients complicated by CI had poor prognosis despite adjunctive dexamethasone treatment. Copyright © 2005 S. Karger AG.
Persistent Identifierhttp://hdl.handle.net/10722/78541
ISSN
2015 Impact Factor: 3.359
2015 SCImago Journal Rankings: 1.744
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KHen_HK
dc.contributor.authorCheung, RTFen_HK
dc.contributor.authorLee, Ren_HK
dc.contributor.authorMak, Wen_HK
dc.contributor.authorHo, SLen_HK
dc.date.accessioned2010-09-06T07:44:01Z-
dc.date.available2010-09-06T07:44:01Z-
dc.date.issued2005en_HK
dc.identifier.citationCerebrovascular Diseases, 2005, v. 19 n. 6, p. 391-395en_HK
dc.identifier.issn1015-9770en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78541-
dc.description.abstractCerebral infarction (CI) is a serious complication of tuberculous meningitis (TBM). It can be asymptomatic or symptomatic, causing stroke. We studied 40 TBM patients. All had initial CT brain scan, CT/MRI brain scan 3 months later and urgent CT brain scan for deterioration. CI was classified into lacunar infarction (LI) or large artery infarction (LAI). Twelve (30%) had CI, in 9 (23%) it was symptomatic and in 3 (8%) silent. Seven (58%) had LAI ± LI. Eight (67%) had multiple CI. Two died from brainstem CI and 6 were dependent at 1 year. Patients with LAI might develop posterior circulation CI more frequently than those with LI only. CI is a common complication of TBM locally, with LAI and multiple CI being common. Two thirds of TBM patients complicated by CI had poor prognosis despite adjunctive dexamethasone treatment. Copyright © 2005 S. Karger AG.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/CEDen_HK
dc.relation.ispartofCerebrovascular Diseasesen_HK
dc.rightsCerebrovascular Diseases. Copyright © S Karger AG.en_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAnti-Inflammatory Agents - therapeutic useen_HK
dc.subject.meshCerebral Infarction - etiology - radiographyen_HK
dc.subject.meshDexamethasone - therapeutic useen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMagnetic Resonance Imagingen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshTuberculosis, Meningeal - complications - drug therapy - radiographyen_HK
dc.titleCerebral infarcts complicating tuberculous meningitisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1015-9770&volume=19&issue=6&spage=391&epage=395&date=2005&atitle=Cerebral+infarcts+complicating+tuberculous+meningitisen_HK
dc.identifier.emailCheung, RTF:rtcheung@hku.hken_HK
dc.identifier.emailHo, SL:slho@hku.hken_HK
dc.identifier.authorityCheung, RTF=rp00434en_HK
dc.identifier.authorityHo, SL=rp00240en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000085568en_HK
dc.identifier.pmid15863982-
dc.identifier.scopuseid_2-s2.0-21344447963en_HK
dc.identifier.hkuros99208en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-21344447963&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue6en_HK
dc.identifier.spage391en_HK
dc.identifier.epage395en_HK
dc.identifier.isiWOS:000230134000006-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridChan, KH=7406034963en_HK
dc.identifier.scopusauthoridCheung, RTF=7202397498en_HK
dc.identifier.scopusauthoridLee, R=7408203830en_HK
dc.identifier.scopusauthoridMak, W=22948344000en_HK
dc.identifier.scopusauthoridHo, SL=25959633500en_HK

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