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Article: Insulinoma

TitleInsulinoma
Authors
Issue Date2000
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-endocrinology.com
Citation
Current Opinion In Endocrinology And Diabetes, 2000, v. 7 n. 2, p. 83-88 How to Cite?
AbstractInsulinoma is the most common pancreatic islet cell tumor, usually presenting with symptoms of neuroglycopenia. Diagnosis depends on a high index of suspicion, together with the demonstration of endogenous hyperinsulinemic hypoglycemia. Although the requirement for preoperative localization is controversial, the minimally invasive but highly sensitive endoscopic ultrasonography allows for a more focused surgery, shorter exploration time, and the option of laparoscopic surgery. Intra-arterial calcium stimulation test can be considered in persistent or possibly multifocal disease. Intraoperative ultrasonography is also recommended to assist tumor localization and minimize complications. The use of a biostator or rapid insulin assays intraoperatively may be helpful if multiple lesions are present. The surgical cure rate for benign insulinomas approaches 100%. For those with residual or metastatic disease, symptomatic control can be achieved with diazoxide or somatostatin analogues. Multimodality therapy is usually required for metastatic disease: with control of hypoglycemia, prolonged symptom-free survival can be expected. (C) 2000 Lippicott Williams and Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/78528
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorTso, AWKen_HK
dc.contributor.authorLam, KSLen_HK
dc.date.accessioned2010-09-06T07:43:53Z-
dc.date.available2010-09-06T07:43:53Z-
dc.date.issued2000en_HK
dc.identifier.citationCurrent Opinion In Endocrinology And Diabetes, 2000, v. 7 n. 2, p. 83-88en_HK
dc.identifier.issn1068-3097en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78528-
dc.description.abstractInsulinoma is the most common pancreatic islet cell tumor, usually presenting with symptoms of neuroglycopenia. Diagnosis depends on a high index of suspicion, together with the demonstration of endogenous hyperinsulinemic hypoglycemia. Although the requirement for preoperative localization is controversial, the minimally invasive but highly sensitive endoscopic ultrasonography allows for a more focused surgery, shorter exploration time, and the option of laparoscopic surgery. Intra-arterial calcium stimulation test can be considered in persistent or possibly multifocal disease. Intraoperative ultrasonography is also recommended to assist tumor localization and minimize complications. The use of a biostator or rapid insulin assays intraoperatively may be helpful if multiple lesions are present. The surgical cure rate for benign insulinomas approaches 100%. For those with residual or metastatic disease, symptomatic control can be achieved with diazoxide or somatostatin analogues. Multimodality therapy is usually required for metastatic disease: with control of hypoglycemia, prolonged symptom-free survival can be expected. (C) 2000 Lippicott Williams and Wilkins, Inc.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-endocrinology.comen_HK
dc.relation.ispartofCurrent Opinion in Endocrinology and Diabetesen_HK
dc.rightsCurrent Opinion in Endocrinology & Diabetes. Copyright © Lippincott Williams & Wilkins.en_HK
dc.titleInsulinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1068-3097&volume=7&spage=83&epage=88&date=2000&atitle=Insulinomaen_HK
dc.identifier.emailTso, AWK: awk.tso@gmail.comen_HK
dc.identifier.emailLam, KSL: ksllam@hku.hken_HK
dc.identifier.authorityTso, AWK=rp00535en_HK
dc.identifier.authorityLam, KSL=rp00343en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00060793-200004000-00007en_HK
dc.identifier.scopuseid_2-s2.0-0034070645en_HK
dc.identifier.hkuros51277en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034070645&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume7en_HK
dc.identifier.issue2en_HK
dc.identifier.spage83en_HK
dc.identifier.epage88en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTso, AWK=6701371436en_HK
dc.identifier.scopusauthoridLam, KSL=8082870600en_HK

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