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Article: Total thyroidectomy replaces subtotal thyroidectomy as the preferred surgical treatment for Graves' disease
Title | Total thyroidectomy replaces subtotal thyroidectomy as the preferred surgical treatment for Graves' disease |
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Authors | |
Keywords | Complication Follow up Graves' disease Recurrence Subtotal thyroidectomy Total thyroidectomy |
Issue Date | 2005 |
Publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANS |
Citation | Anz Journal Of Surgery, 2005, v. 75 n. 7, p. 528-531 How to Cite? |
Abstract | Background: Total thyroidectomy is increasingly being adopted for patients requiring surgical treatment for Graves' disease based on a comparable surgical risk and the lack of recurrence, as well as the questionable ability of subtotal thyroidectomy to maintain euthyroidism. The purpose of the present paper was to evaluate its safety and efficiency. Methods: Total thyroidectomy was adopted as part of the routine surgical treatment for Graves' disease from 2000. Patients who underwent subtotal thyroidectomy (STT) from 1995 to 1999 (n = 119) were compared with those who underwent total thyroidectomy (TT) from 2000 to 2003 (n = 98) with respect to immediate postoperative morbidity and long-term outcome. Results: Fourteen (11.8%) and 22 patients (22.4%) required calcium supplement on discharge in the STT and TT groups, respectively (P < 0.05). One (0.8%) and three patients (3.1%) developed permanent hypocalcaemia, respectively. Transient recurrent laryngeal nerve palsy occurred in 9.2% (n = 11) and 5.1% (n = 5) of patients or 5.0% and 2.6% of nerves at risk after STT and TT, respectively. None of the patients had permanent nerve palsy. The estimated blood loss was less and hospital stay shorter after TT. During a mean follow up of 64 months, 86 patients (72.3%) in the STT group required thyroxine replacement and seven patients (5.9%) developed relapse. Conclusion: Subtotal thyroidectomy was associated with relapse as well as hypothyroidism in a significant proportion of patients during long-term follow up. Total thyroidectomy can be performed as safely as STT and should be recommended as the procedure of choice for patients requiring surgical treatment for Graves' disease. |
Persistent Identifier | http://hdl.handle.net/10722/77982 |
ISSN | 2023 Impact Factor: 1.5 2023 SCImago Journal Rankings: 0.453 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ku, CF | en_HK |
dc.contributor.author | Lo, CY | en_HK |
dc.contributor.author | Chan, WF | en_HK |
dc.contributor.author | Kung, AWC | en_HK |
dc.contributor.author | Lam, KSL | en_HK |
dc.date.accessioned | 2010-09-06T07:37:52Z | - |
dc.date.available | 2010-09-06T07:37:52Z | - |
dc.date.issued | 2005 | en_HK |
dc.identifier.citation | Anz Journal Of Surgery, 2005, v. 75 n. 7, p. 528-531 | en_HK |
dc.identifier.issn | 1445-1433 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/77982 | - |
dc.description.abstract | Background: Total thyroidectomy is increasingly being adopted for patients requiring surgical treatment for Graves' disease based on a comparable surgical risk and the lack of recurrence, as well as the questionable ability of subtotal thyroidectomy to maintain euthyroidism. The purpose of the present paper was to evaluate its safety and efficiency. Methods: Total thyroidectomy was adopted as part of the routine surgical treatment for Graves' disease from 2000. Patients who underwent subtotal thyroidectomy (STT) from 1995 to 1999 (n = 119) were compared with those who underwent total thyroidectomy (TT) from 2000 to 2003 (n = 98) with respect to immediate postoperative morbidity and long-term outcome. Results: Fourteen (11.8%) and 22 patients (22.4%) required calcium supplement on discharge in the STT and TT groups, respectively (P < 0.05). One (0.8%) and three patients (3.1%) developed permanent hypocalcaemia, respectively. Transient recurrent laryngeal nerve palsy occurred in 9.2% (n = 11) and 5.1% (n = 5) of patients or 5.0% and 2.6% of nerves at risk after STT and TT, respectively. None of the patients had permanent nerve palsy. The estimated blood loss was less and hospital stay shorter after TT. During a mean follow up of 64 months, 86 patients (72.3%) in the STT group required thyroxine replacement and seven patients (5.9%) developed relapse. Conclusion: Subtotal thyroidectomy was associated with relapse as well as hypothyroidism in a significant proportion of patients during long-term follow up. Total thyroidectomy can be performed as safely as STT and should be recommended as the procedure of choice for patients requiring surgical treatment for Graves' disease. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANS | en_HK |
dc.relation.ispartof | ANZ Journal of Surgery | en_HK |
dc.rights | The definitive version is available at www3.interscience.wiley.com | - |
dc.subject | Complication | en_HK |
dc.subject | Follow up | en_HK |
dc.subject | Graves' disease | en_HK |
dc.subject | Recurrence | en_HK |
dc.subject | Subtotal thyroidectomy | en_HK |
dc.subject | Total thyroidectomy | en_HK |
dc.subject.mesh | Adolescent | - |
dc.subject.mesh | Adult | - |
dc.subject.mesh | Graves Disease - surgery | - |
dc.subject.mesh | Postoperative Complications | - |
dc.subject.mesh | Thyroidectomy - methods | - |
dc.title | Total thyroidectomy replaces subtotal thyroidectomy as the preferred surgical treatment for Graves' disease | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1445-1433&volume=75&issue=7&spage=528&epage=531&date=2005&atitle=Total+thyroidectomy+replaces+subtotal+thyroidectomy+as+the+preferred+surgical+treatment+for+Graves%27+disease | en_HK |
dc.identifier.email | Kung, AWC:awckung@hku.hk | en_HK |
dc.identifier.email | Lam, KSL:ksllam@hku.hk | en_HK |
dc.identifier.authority | Kung, AWC=rp00368 | en_HK |
dc.identifier.authority | Lam, KSL=rp00343 | en_HK |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1111/j.1445-2197.2005.03441.x | en_HK |
dc.identifier.pmid | 15972039 | en_HK |
dc.identifier.scopus | eid_2-s2.0-22344456326 | en_HK |
dc.identifier.hkuros | 98469 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-22344456326&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 75 | en_HK |
dc.identifier.issue | 7 | en_HK |
dc.identifier.spage | 528 | en_HK |
dc.identifier.epage | 531 | en_HK |
dc.identifier.isi | WOS:000229783500007 | - |
dc.publisher.place | Australia | en_HK |
dc.identifier.scopusauthorid | Ku, CF=7101950635 | en_HK |
dc.identifier.scopusauthorid | Lo, CY=16417392800 | en_HK |
dc.identifier.scopusauthorid | Chan, WF=7403918455 | en_HK |
dc.identifier.scopusauthorid | Kung, AWC=7102322339 | en_HK |
dc.identifier.scopusauthorid | Lam, KSL=8082870600 | en_HK |
dc.identifier.issnl | 1445-1433 | - |