Article: Adipose tissue and the metabolic syndrome: Focusing on adiponectin and several novel adipokines

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TitleAdipose tissue and the metabolic syndrome: Focusing on adiponectin and several novel adipokines
AuthorsTso, AWK1
Xu, A1
Chow, WS1
Lam, KSL1
KeywordsAdipocyte fatty acid-binding protein
Adipokines
Adiponectin
Insulin resistance
Lipocalin-2
Retinol-binding protein 4
The Metabolic syndrome
Issue Date2008
PublisherFuture Medicine Ltd. The Journal's web site is located at http://www.futuremedicine.com/loi/bmm
CitationBiomarkers In Medicine, 2008, v. 2 n. 3, p. 239-252 [How to Cite?]
DOI: http://dx.doi.org/10.2217/17520363.2.3.239
AbstractThe metabolic syndrome represents a cluster of metabolic risk factors that predispose an individual to an increased risk for Type 2 diabetes, cardiovascular diseases and their associated morbidity and mortality. Visceral obesity is thought to be a major culprit. Adipokines secreted from the adipose tissue are now believed to be key factors mediating the metabolic and inflammatory effects of obesity. In this review, we shall examine the evidence suggesting that several novel adipokines, adiponectin, adipocyte fatty acid-binding protein, retinol-binding protein-4 and lipocalin-2, may hold promise as important clinical biomarkers to identify individuals at risk for the metabolic syndrome and related comorbidities. © 2008 Future Medicine Ltd.
ISSN1752-0363
2011 Impact Factor: 2.63
2011 SCImago Journal Rankings: 0.163
DOIhttp://dx.doi.org/10.2217/17520363.2.3.239
ISI Accession Number IDWOS:000258921400009
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorTso, AWK
dc.contributor.authorXu, A
dc.contributor.authorChow, WS
dc.contributor.authorLam, KSL
dc.date.accessioned2010-09-06T07:33:09Z
dc.date.available2010-09-06T07:33:09Z
dc.date.issued2008
dc.description.abstractThe metabolic syndrome represents a cluster of metabolic risk factors that predispose an individual to an increased risk for Type 2 diabetes, cardiovascular diseases and their associated morbidity and mortality. Visceral obesity is thought to be a major culprit. Adipokines secreted from the adipose tissue are now believed to be key factors mediating the metabolic and inflammatory effects of obesity. In this review, we shall examine the evidence suggesting that several novel adipokines, adiponectin, adipocyte fatty acid-binding protein, retinol-binding protein-4 and lipocalin-2, may hold promise as important clinical biomarkers to identify individuals at risk for the metabolic syndrome and related comorbidities. © 2008 Future Medicine Ltd.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationBiomarkers In Medicine, 2008, v. 2 n. 3, p. 239-252 [How to Cite?]
DOI: http://dx.doi.org/10.2217/17520363.2.3.239
dc.identifier.doihttp://dx.doi.org/10.2217/17520363.2.3.239
dc.identifier.epage252
dc.identifier.hkuros145457
dc.identifier.isiWOS:000258921400009
dc.identifier.issn1752-0363
2011 Impact Factor: 2.63
2011 SCImago Journal Rankings: 0.163
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.scopuseid_2-s2.0-48249114800
dc.identifier.spage239
dc.identifier.urihttp://hdl.handle.net/10722/77553
dc.identifier.volume2
dc.languageeng
dc.publisherFuture Medicine Ltd. The Journal's web site is located at http://www.futuremedicine.com/loi/bmm
dc.publisher.placeUnited Kingdom
dc.relation.ispartofBiomarkers in Medicine
dc.relation.referencesReferences in Scopus
dc.subjectAdipocyte fatty acid-binding protein
dc.subjectAdipokines
dc.subjectAdiponectin
dc.subjectInsulin resistance
dc.subjectLipocalin-2
dc.subjectRetinol-binding protein 4
dc.subjectThe Metabolic syndrome
dc.titleAdipose tissue and the metabolic syndrome: Focusing on adiponectin and several novel adipokines
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong