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Article: Acute cholangitis - Predictive factors for emergency ERCP

TitleAcute cholangitis - Predictive factors for emergency ERCP
Authors
Issue Date2001
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2001, v. 15 n. 10, p. 1633-1637 How to Cite?
AbstractBackground: Acute cholangitis varies in severity from a mild form to severe cases which require urgent biliary decompression. Aim: This study was undertaken in order to develop a prognostic scoring system that can be used to predict which patients are likely to require emergency endoscopic retrograde cholangiopancreatogram (ERCP) upon admission. Methods: This is a prospective study of 142 consecutive patients with acute cholangitis. Emergency ERCP was performed in patients who did not respond to medical therapy. Results: Thirty-one patients (21.8%) required emergency ERCP. A maximum heart rate of more than 100/min, albumin of less than 30 g/L, bilirubin of more than 50 μmol/L and prothrombin time of more than 14 s on admission were associated with failure of medical treatment and the need for emergency ERCP (P = 0.001, < 0.001, 0.006 and 0.004, respectively). By using these four factors in a scoring system, 50.7% of those with a score of one or more required emergency ERCP compared with 1.5% of those with none of the four risk factors (P < 0.001). This scoring system has a sensitivity of 96.8% and a specificity of 59.6%. Conclusions: As patients with severe acute cholangitis show a higher mortality, we recommend that emergency ERCP be performed in patients with one or more of the four prognostic factors.
Persistent Identifierhttp://hdl.handle.net/10722/77297
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHui, CKen_HK
dc.contributor.authorLai, KCen_HK
dc.contributor.authorYuen, MFen_HK
dc.contributor.authorNg, Men_HK
dc.contributor.authorLai, CLen_HK
dc.contributor.authorLam, SKen_HK
dc.date.accessioned2010-09-06T07:30:22Z-
dc.date.available2010-09-06T07:30:22Z-
dc.date.issued2001en_HK
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2001, v. 15 n. 10, p. 1633-1637en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77297-
dc.description.abstractBackground: Acute cholangitis varies in severity from a mild form to severe cases which require urgent biliary decompression. Aim: This study was undertaken in order to develop a prognostic scoring system that can be used to predict which patients are likely to require emergency endoscopic retrograde cholangiopancreatogram (ERCP) upon admission. Methods: This is a prospective study of 142 consecutive patients with acute cholangitis. Emergency ERCP was performed in patients who did not respond to medical therapy. Results: Thirty-one patients (21.8%) required emergency ERCP. A maximum heart rate of more than 100/min, albumin of less than 30 g/L, bilirubin of more than 50 μmol/L and prothrombin time of more than 14 s on admission were associated with failure of medical treatment and the need for emergency ERCP (P = 0.001, < 0.001, 0.006 and 0.004, respectively). By using these four factors in a scoring system, 50.7% of those with a score of one or more required emergency ERCP compared with 1.5% of those with none of the four risk factors (P < 0.001). This scoring system has a sensitivity of 96.8% and a specificity of 59.6%. Conclusions: As patients with severe acute cholangitis show a higher mortality, we recommend that emergency ERCP be performed in patients with one or more of the four prognostic factors.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.subject.meshAcute Diseaseen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAlbumins - analysisen_HK
dc.subject.meshBilirubin - blooden_HK
dc.subject.meshCholangiopancreatography, Endoscopic Retrogradeen_HK
dc.subject.meshCholangitis - diagnosis - physiopathology - surgeryen_HK
dc.subject.meshDecompression, Surgicalen_HK
dc.subject.meshEmergenciesen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHeart Rateen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshPredictive Value of Testsen_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshProthrombin Timeen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSensitivity and Specificityen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleAcute cholangitis - Predictive factors for emergency ERCPen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=15&issue=10&spage=1633&epage=1637&date=2001&atitle=Acute+cholangitis+-+predictive+factors+for+emergency+ERCP.en_HK
dc.identifier.emailYuen, MF:mfyuen@hkucc.hku.hken_HK
dc.identifier.emailLai, CL:hrmelcl@hku.hken_HK
dc.identifier.authorityYuen, MF=rp00479en_HK
dc.identifier.authorityLai, CL=rp00314en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1046/j.1365-2036.2001.01071.xen_HK
dc.identifier.pmid11564004-
dc.identifier.scopuseid_2-s2.0-0034789256en_HK
dc.identifier.hkuros66979en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034789256&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue10en_HK
dc.identifier.spage1633en_HK
dc.identifier.epage1637en_HK
dc.identifier.isiWOS:000171585000015-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHui, CK=7202876933en_HK
dc.identifier.scopusauthoridLai, KC=7402135595en_HK
dc.identifier.scopusauthoridYuen, MF=7102031955en_HK
dc.identifier.scopusauthoridNg, M=7202076310en_HK
dc.identifier.scopusauthoridLai, CL=7403086396en_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK

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