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Article: Giant growth-hormone secreting pituitary tumour with extracranial extension

TitleGiant growth-hormone secreting pituitary tumour with extracranial extension
Authors
Issue Date1996
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ARA
Citation
Australasian Radiology, 1996, v. 40 n. 1, p. 88-90 How to Cite?
AbstractA 19 year old female patient with typical features of acromegaly was found to have an extensive pituitary tumour with suprasellar, lateral and inferior extensions. Magnetic resonance imaging (MRI) also showed a portion of the tumour extending from the right cavernous sinus through the foramen ovale to become extracranial. Serum growth hormone (CH) was 52.6 mU/L basally and remained elevated after oral glucose, confirming the diagnosis of acromegaly. Treatment with the long-acting somatostatin analogue, octreotide, for 6 months led to a 30% reduction in tumour volume of the intracranial portion but no effect on the extracranial and sphenoidal extensions. She was subsequently treated with trans-sphenoidal surgery followed by external irradiation. The possibility of perineural spread of the tumour was considered.
Persistent Identifierhttp://hdl.handle.net/10722/77193
ISSN
2009 Impact Factor: 0.51
References

 

DC FieldValueLanguage
dc.contributor.authorIp, TPen_HK
dc.contributor.authorChan, FLen_HK
dc.contributor.authorKung, AWCen_HK
dc.contributor.authorLam, KSLen_HK
dc.date.accessioned2010-09-06T07:29:16Z-
dc.date.available2010-09-06T07:29:16Z-
dc.date.issued1996en_HK
dc.identifier.citationAustralasian Radiology, 1996, v. 40 n. 1, p. 88-90en_HK
dc.identifier.issn0004-8461en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77193-
dc.description.abstractA 19 year old female patient with typical features of acromegaly was found to have an extensive pituitary tumour with suprasellar, lateral and inferior extensions. Magnetic resonance imaging (MRI) also showed a portion of the tumour extending from the right cavernous sinus through the foramen ovale to become extracranial. Serum growth hormone (CH) was 52.6 mU/L basally and remained elevated after oral glucose, confirming the diagnosis of acromegaly. Treatment with the long-acting somatostatin analogue, octreotide, for 6 months led to a 30% reduction in tumour volume of the intracranial portion but no effect on the extracranial and sphenoidal extensions. She was subsequently treated with trans-sphenoidal surgery followed by external irradiation. The possibility of perineural spread of the tumour was considered.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ARAen_HK
dc.relation.ispartofAustralasian Radiologyen_HK
dc.subject.meshAcromegaly - etiologyen_HK
dc.subject.meshAdenoma - diagnosis - secretionen_HK
dc.subject.meshAdulten_HK
dc.subject.meshCavernous Sinus - pathologyen_HK
dc.subject.meshDiagnosis, Differentialen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGrowth Hormone - secretionen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMagnetic Resonance Imagingen_HK
dc.subject.meshPituitary Gland - pathologyen_HK
dc.subject.meshPituitary Neoplasms - diagnosis - secretionen_HK
dc.titleGiant growth-hormone secreting pituitary tumour with extracranial extensionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0004-8461&volume=40&spage=88&epage=90&date=1996&atitle=Giant+growth-hormone+secreting+pituitary+tumour+with+extracranial+extension.en_HK
dc.identifier.emailKung, AWC:awckung@hku.hken_HK
dc.identifier.emailLam, KSL:ksllam@hku.hken_HK
dc.identifier.authorityKung, AWC=rp00368en_HK
dc.identifier.authorityLam, KSL=rp00343en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid8838899-
dc.identifier.scopuseid_2-s2.0-0030010916en_HK
dc.identifier.hkuros22842en_HK
dc.identifier.hkuros10872-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030010916&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume40en_HK
dc.identifier.issue1en_HK
dc.identifier.spage88en_HK
dc.identifier.epage90en_HK
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridIp, TP=7003866522en_HK
dc.identifier.scopusauthoridChan, FL=7202586444en_HK
dc.identifier.scopusauthoridKung, AWC=7102322339en_HK
dc.identifier.scopusauthoridLam, KSL=8082870600en_HK

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