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Article: HBsAg seroclearance in the natural history of chronic hepatitis B infection

TitleHBsAg seroclearance in the natural history of chronic hepatitis B infection
Authors
Yuen, MFLai, CL
Issue Date2006
PublisherSpringer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/
Citation
Current Hepatitis Reports, 2006, v. 5 n. 1, p. 23-26 How to Cite?
DOI: http://dx.doi.org/10.1007/s11901-006-0019-7
AbstractHepatitis B surface antigen (HBsAg) seroclearance is a rare event that occurs in 0.1% to 2% of patients with chronic hepatitis B per year. Patients with HBsAg seroclearance have improvement of liver biochemistry and hepatic necroinflammation. The viral load gradually decreases with time, although some patients still have detectable intrahepatic hepatitis B virus DNA, mainly in the form of covalently closed circular DNA. There is no reduction of the risk of cirrhosis-related complications and hepatocellular carcinoma if HBsAg seroclearance occurs at an older age when cirrhosis has already been established. Copyright © 2006 by Current Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/76911
ISSN
1540-3416
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorYuen, MFen_HK
dc.contributor.authorLai, CLen_HK
dc.date.accessioned2010-09-06T07:26:15Z-
dc.date.available2010-09-06T07:26:15Z-
dc.date.issued2006en_HK
dc.identifier.citationCurrent Hepatitis Reports, 2006, v. 5 n. 1, p. 23-26en_HK
dc.identifier.issn1540-3416en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76911-
dc.description.abstractHepatitis B surface antigen (HBsAg) seroclearance is a rare event that occurs in 0.1% to 2% of patients with chronic hepatitis B per year. Patients with HBsAg seroclearance have improvement of liver biochemistry and hepatic necroinflammation. The viral load gradually decreases with time, although some patients still have detectable intrahepatic hepatitis B virus DNA, mainly in the form of covalently closed circular DNA. There is no reduction of the risk of cirrhosis-related complications and hepatocellular carcinoma if HBsAg seroclearance occurs at an older age when cirrhosis has already been established. Copyright © 2006 by Current Science Inc.en_HK
dc.languageengen_HK
dc.publisherSpringer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/en_HK
dc.relation.ispartofCurrent Hepatitis Reportsen_HK
dc.titleHBsAg seroclearance in the natural history of chronic hepatitis B infectionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1540-3416&volume=5&issue=1&spage=23&epage=26&date=2006&atitle=HBsAg+seroclearance+in+the+natural+history+of+chronic+hepatitis+B+infectionen_HK
dc.identifier.emailYuen, MF:mfyuen@hkucc.hku.hken_HK
dc.identifier.emailLai, CL:hrmelcl@hku.hken_HK
dc.identifier.authorityYuen, MF=rp00479en_HK
dc.identifier.authorityLai, CL=rp00314en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s11901-006-0019-7en_HK
dc.identifier.scopuseid_2-s2.0-33750362674en_HK
dc.identifier.hkuros130708en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33750362674&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue1en_HK
dc.identifier.spage23en_HK
dc.identifier.epage26en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYuen, MF=7102031955en_HK
dc.identifier.scopusauthoridLai, CL=7403086396en_HK
dc.identifier.issnl1540-3416-

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